(12 nodes) MAP2K and MAPK activation network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_07301	Uncharacterized protein. (151 aa)
	MAC_02314	MAP kinase kinase EMK1. (506 aa)
	MAC_03304	Uncharacterized protein. (652 aa)
	MAC_03315	Uncharacterized protein. (436 aa)
	MAC_04869	Mitogen activated protein kinase kinase. (658 aa)
	MAC_05487	Protein kinase domain-containing protein. (728 aa)
	MAC_05974	Uncharacterized protein. (898 aa)
	MAC_06184	Uncharacterized protein. (739 aa)
	MAC_00065	Uncharacterized protein. (224 aa)
	MAC_00098	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
	MAC_09508	Uncharacterized protein. (135 aa)
	MAC_09026	Protein kinase domain-containing protein. (93 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00065	MAC_00098	E9DRZ2	E9DS25	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.479
MAC_00098	MAC_00065	E9DS25	E9DRZ2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.479
MAC_00098	MAC_02314	E9DS25	E9DXG6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase kinase EMK1.	0.998
MAC_00098	MAC_03304	E9DS25	E9E028	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.479
MAC_00098	MAC_03315	E9DS25	E9E039	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.479
MAC_00098	MAC_04869	E9DS25	E9E4S1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen activated protein kinase kinase.	0.855
MAC_00098	MAC_05487	E9DS25	E9E6I9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.539
MAC_00098	MAC_06184	E9DS25	E9E8I6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.479
MAC_00098	MAC_09026	E9DS25	E9EGM8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.479
MAC_02314	MAC_00098	E9DXG6	E9DS25	MAP kinase kinase EMK1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.998
MAC_02314	MAC_04869	E9DXG6	E9E4S1	MAP kinase kinase EMK1.	Mitogen activated protein kinase kinase.	0.744
MAC_02314	MAC_05974	E9DXG6	E9E7X6	MAP kinase kinase EMK1.	Uncharacterized protein.	0.589
MAC_03304	MAC_00098	E9E028	E9DS25	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.479
MAC_03315	MAC_00098	E9E039	E9DS25	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.479
MAC_04869	MAC_00098	E9E4S1	E9DS25	Mitogen activated protein kinase kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.855
MAC_04869	MAC_02314	E9E4S1	E9DXG6	Mitogen activated protein kinase kinase.	MAP kinase kinase EMK1.	0.744
MAC_04869	MAC_05974	E9E4S1	E9E7X6	Mitogen activated protein kinase kinase.	Uncharacterized protein.	0.589
MAC_05487	MAC_00098	E9E6I9	E9DS25	Protein kinase domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.539
MAC_05974	MAC_02314	E9E7X6	E9DXG6	Uncharacterized protein.	MAP kinase kinase EMK1.	0.589
MAC_05974	MAC_04869	E9E7X6	E9E4S1	Uncharacterized protein.	Mitogen activated protein kinase kinase.	0.589