STRINGSTRING
MAC_07699 MAC_07699 MAC_08048 MAC_08048 MAC_08177 MAC_08177 MAC_08697 MAC_08697 MAC_08335 MAC_08335 MAC_08740 MAC_08740 MAC_00150 MAC_00150 MAC_00073 MAC_00073 MAC_08937 MAC_08937 MAC_00653 MAC_00653 MCM7 MCM7 MAC_01210 MAC_01210 MAC_01288 MAC_01288 MAC_01509 MAC_01509 MAC_01906 MAC_01906 MAC_02019 MAC_02019 MAC_08833 MAC_08833 MAC_02318 MAC_02318 MAC_02629 MAC_02629 MAC_02630 MAC_02630 MAC_02716 MAC_02716 MAC_02738 MAC_02738 MAC_02765 MAC_02765 MAC_02820 MAC_02820 MAC_02978 MAC_02978 MAC_09135 MAC_09135 MAC_03387 MAC_03387 MAC_03443 MAC_03443 MAC_03823 MAC_03823 MAC_04156 MAC_04156 MAC_04191 MAC_04191 MAC_09115 MAC_09115 MAC_04324 MAC_04324 MAC_04569 MAC_04569 MAC_04605 MAC_04605 MAC_04669 MAC_04669 MAC_05971 MAC_05971 MAC_05980 MAC_05980 MAC_06483 MAC_06483 MAC_06646 MAC_06646 MAC_06647 MAC_06647 MAC_06747 MAC_06747 MAC_07070 MAC_07070 MAC_07468 MAC_07468
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAC_07699Cell cycle protein kinase, putative. (475 aa)
MAC_08048Origin recognition complex subunit Orc5. (359 aa)
MAC_08177DNA helicase; Belongs to the MCM family. (1015 aa)
MAC_08697Uncharacterized protein. (1695 aa)
MAC_08335DNA polymerase. (1464 aa)
MAC_08740DNA replication factor A subunit Ssb3. (101 aa)
MAC_00150Pol protein. (217 aa)
MAC_00073Origin recognition complex subunit 6 (ORC6). (379 aa)
MAC_08937Origin recognition complex subunit 2, putative. (589 aa)
MAC_00653Putative replication factor-a protein. (278 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (810 aa)
MAC_01210DNA helicase; Belongs to the MCM family. (867 aa)
MAC_01288Origin recognition complex subunit Orc4, putative. (754 aa)
MAC_01509Uncharacterized protein. (143 aa)
MAC_01906DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2212 aa)
MAC_02019UDP-galactopyranose mutase. (548 aa)
MAC_08833DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (501 aa)
MAC_02318Putative DNA directed DNA polymerase II chain B. (759 aa)
MAC_02629DnaJ domain-containing protein. (297 aa)
MAC_02630OB-fold nucleic acid binding domain protein. (277 aa)
MAC_02716Cell division cycle protein. (782 aa)
MAC_02738DBF zinc finger domain-containing protein. (654 aa)
MAC_02765Pol protein. (874 aa)
MAC_02820Fungal specific transcription factor, putative. (130 aa)
MAC_02978DNA helicase; Belongs to the MCM family. (1019 aa)
MAC_09135Putative sna41 protein. (859 aa)
MAC_03387Telomere silencing protein Zds1, putative. (992 aa)
MAC_03443Cell division control protein. (337 aa)
MAC_03823Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (595 aa)
MAC_04156Origin recognition complex subunit. (651 aa)
MAC_04191CBF/NF-Y family transcription factor. (270 aa)
MAC_09115DNA helicase; Belongs to the MCM family. (980 aa)
MAC_04324TPR Domain containing protein. (550 aa)
MAC_04569Gag protein. (541 aa)
MAC_04605Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (433 aa)
MAC_04669DNA primase; Belongs to the eukaryotic-type primase small subunit family. (512 aa)
MAC_05971DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (616 aa)
MAC_05980DNA helicase; Belongs to the MCM family. (721 aa)
MAC_06483Negative regulator of the PHO system; Belongs to the protein kinase superfamily. (327 aa)
MAC_06646Pol protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (868 aa)
MAC_06647Pol protein. (231 aa)
MAC_06747Histone-like transcription factor and archaeal histone family protein. (194 aa)
MAC_07070Cell division control protein; Belongs to the CDC6/cdc18 family. (608 aa)
MAC_07468CCHC-type domain-containing protein. (206 aa)
Your Current Organism:
Metarhizium acridum
NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.