(32 nodes) Branched-chain amino acid catabolism network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

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co-expression

protein homology

Your Input:
	MAC_09599	Enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (294 aa)
	MAC_00274	Enoyl-CoA hydratase/carnithine racemase. (422 aa)
	MAC_00471	Protein-serine/threonine kinase. (427 aa)
	MAC_00631	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	MAC_00644	Putative S-adenosylmethionine/tRNA-ribosyltransferase-isomerase. (324 aa)
	MAC_00832	Isovaleryl-CoA dehydrogenase. (401 aa)
	MAC_00833	Methylcrotonoyl-CoA carboxylase beta chain. (569 aa)
	MAC_01323	Branched-chain amino acid aminotransferase, putative. (452 aa)
	MAC_01431	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (345 aa)
	MAC_02677	Chlorocatechol 1,2-dioxygenase. (340 aa)
	MAC_02705	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (411 aa)
	MAC_02860	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (393 aa)
	MAC_02887	Branched-chain-amino-acid aminotransferase 5. (361 aa)
	MAC_03390	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (450 aa)
	MAC_03510	2-oxoisovalerate dehydrogenase beta subunit. (401 aa)
	MAC_03793	Methylmalonate semialdehyde dehydrogenase. (575 aa)
	MAC_03803	Enoyl-CoA hydratase, putative. (183 aa)
	MAC_04541	Branched-chain-amino-acid aminotransferase. (398 aa)
	MAC_04972	Uncharacterized protein. (128 aa)
	MAC_04976	Subgroup IIIi aminotransferase, putative. (178 aa)
	MAC_05032	Uncharacterized protein. (281 aa)
	MAC_05504	3-hydroxyacyl-CoA dehydrogenase. (259 aa)
	MAC_05798	Short chain dehydrogenase/reductase family. (258 aa)
	MAC_05969	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (478 aa)
	MAC_06831	Carnitinyl-CoA dehydratase, putative. (306 aa)
	MAC_07082	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (504 aa)
	MAC_07263	Enoyl-CoA hydratase/isomerase. (300 aa)
	MAC_07432	Methylglutaconyl-CoA hydratase, putative. (316 aa)
	MAC_07838	Enoyl-CoA hydratase/isomerase family protein. (153 aa)
	MAC_08637	Protein-serine/threonine kinase. (390 aa)
	MAC_09313	Enoyl-CoA hydratase. (299 aa)
	MAC_09587	Enoyl-CoA hydratase/isomerase family protein. (315 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00274	MAC_00832	E9DRA5	E9DTJ4	Enoyl-CoA hydratase/carnithine racemase.	Isovaleryl-CoA dehydrogenase.	0.513
MAC_00274	MAC_00833	E9DRA5	E9DTJ5	Enoyl-CoA hydratase/carnithine racemase.	Methylcrotonoyl-CoA carboxylase beta chain.	0.550
MAC_00274	MAC_02677	E9DRA5	E9DYI0	Enoyl-CoA hydratase/carnithine racemase.	Chlorocatechol 1,2-dioxygenase.	0.513
MAC_00274	MAC_05504	E9DRA5	E9E6K6	Enoyl-CoA hydratase/carnithine racemase.	3-hydroxyacyl-CoA dehydrogenase.	0.493
MAC_00274	MAC_05798	E9DRA5	E9E7F0	Enoyl-CoA hydratase/carnithine racemase.	Short chain dehydrogenase/reductase family.	0.493
MAC_00274	MAC_05969	E9DRA5	E9E7X1	Enoyl-CoA hydratase/carnithine racemase.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.485
MAC_00274	MAC_09313	E9DRA5	E9EHG5	Enoyl-CoA hydratase/carnithine racemase.	Enoyl-CoA hydratase.	0.531
MAC_00471	MAC_03390	E9DS73	E9E0J2	Protein-serine/threonine kinase.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.524
MAC_00471	MAC_03510	E9DS73	E9E0W2	Protein-serine/threonine kinase.	2-oxoisovalerate dehydrogenase beta subunit.	0.493
MAC_00631	MAC_00832	E9DSN3	E9DTJ4	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Isovaleryl-CoA dehydrogenase.	0.949
MAC_00631	MAC_00833	E9DSN3	E9DTJ5	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Methylcrotonoyl-CoA carboxylase beta chain.	0.955
MAC_00631	MAC_01431	E9DSN3	E9DV41	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.533
MAC_00631	MAC_02677	E9DSN3	E9DYI0	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Chlorocatechol 1,2-dioxygenase.	0.520
MAC_00631	MAC_05504	E9DSN3	E9E6K6	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyacyl-CoA dehydrogenase.	0.736
MAC_00631	MAC_05798	E9DSN3	E9E7F0	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Short chain dehydrogenase/reductase family.	0.493
MAC_00631	MAC_05969	E9DSN3	E9E7X1	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.956
MAC_00631	MAC_07838	E9DSN3	E9ED90	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA hydratase/isomerase family protein.	0.920
MAC_00644	MAC_00832	E9DSP6	E9DTJ4	Putative S-adenosylmethionine/tRNA-ribosyltransferase-isomerase.	Isovaleryl-CoA dehydrogenase.	0.520
MAC_00644	MAC_00833	E9DSP6	E9DTJ5	Putative S-adenosylmethionine/tRNA-ribosyltransferase-isomerase.	Methylcrotonoyl-CoA carboxylase beta chain.	0.577
MAC_00644	MAC_01431	E9DSP6	E9DV41	Putative S-adenosylmethionine/tRNA-ribosyltransferase-isomerase.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.533