(35 nodes) Chromosome Maintenance network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_02924	Putative neurofilament triplet H1 protein. (631 aa)
	MAC_09789	Putative neurofilament triplet H1 protein. (236 aa)
	MAC_09745	ATP-dependent DNA helicase; Belongs to the helicase family. (1946 aa)
	MAC_09744	Putative replicase/helicase/endonuclease. (1668 aa)
	MAC_09582	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (473 aa)
	MAC_09558	SnoaL-like domain-containing protein. (135 aa)
	MAC_09496	ATP-dependent DNA helicase; Belongs to the helicase family. (425 aa)
	MAC_09425	Putative recQ DNA helicase. (297 aa)
	MAC_09239	H/ACA ribonucleoprotein complex subunit, putative. (255 aa)
	MAC_08234	Uncharacterized protein. (619 aa)
	MAC_08183	Uncharacterized protein. (438 aa)
	MAC_07736	Chromatin remodelling complex ATPase chain ISW1. (1120 aa)
	MAC_07230	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
	MAC_00126	Histone H2B; Belongs to the histone H2B family. (137 aa)
	MAC_00148	Uncharacterized protein. (215 aa)
	MAC_00349	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (205 aa)
	MAC_00430	Uncharacterized protein. (127 aa)
	MAC_00498	Telomere-binding alpha subunit central domain-containing protein. (694 aa)
	MAC_00607	SNF2 family helicase/ATPase. (1677 aa)
	MAC_00758	PUA domain-containing protein. (487 aa)
	MAC_01263	WD repeat-containing protein 79. (603 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (915 aa)
	MAC_03019	QDE3 protein. (1698 aa)
	MAC_03224	ATP-dependent DNA helicase; Belongs to the helicase family. (1509 aa)
	MAC_03225	ATP-dependent DNA helicase; Belongs to the helicase family. (1504 aa)
	MAC_03634	DNA polymerase delta subunit 4. (200 aa)
	MAC_03823	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (595 aa)
	MAC_03835	Hydrolase. (206 aa)
	MAC_05126	H/ACA ribonucleoprotein complex subunit 3. (61 aa)
	MAC_05232	TruB family pseudouridylate synthase containing protein. (483 aa)
	MAC_05324	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (898 aa)
	MAC_05651	Sister chromatid cohesion protein Ctf8, putative. (146 aa)
	MAC_05930	Putative Werner syndrome helicase. (551 aa)
	MAC_06354	ATP-dependent DNA helicase; Belongs to the helicase family. (644 aa)
	MAC_06771	AAA domain-containing protein. (958 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00126	MAC_00498	E9DQV7	E9DSA0	Histone H2B; Belongs to the histone H2B family.	Telomere-binding alpha subunit central domain-containing protein.	0.452
MAC_00126	MAC_00607	E9DQV7	E9DSK9	Histone H2B; Belongs to the histone H2B family.	SNF2 family helicase/ATPase.	0.536
MAC_00126	MAC_07230	E9DQV7	E9EBI2	Histone H2B; Belongs to the histone H2B family.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.918
MAC_00126	MAC_07736	E9DQV7	E9ECY8	Histone H2B; Belongs to the histone H2B family.	Chromatin remodelling complex ATPase chain ISW1.	0.932
MAC_00126	MAC_09582	E9DQV7	E9EI84	Histone H2B; Belongs to the histone H2B family.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.886
MAC_00126	MAC_09789	E9DQV7	E9EIU1	Histone H2B; Belongs to the histone H2B family.	Putative neurofilament triplet H1 protein.	0.885
MAC_00148	MAC_00498	E9DQX9	E9DSA0	Uncharacterized protein.	Telomere-binding alpha subunit central domain-containing protein.	0.421
MAC_00148	MAC_03823	E9DQX9	E9E1W8	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.872
MAC_00148	MAC_05930	E9DQX9	E9E7T2	Uncharacterized protein.	Putative Werner syndrome helicase.	0.407
MAC_00148	MAC_06771	E9DQX9	E9EA73	Uncharacterized protein.	AAA domain-containing protein.	0.543
MAC_00148	MAC_08183	E9DQX9	E9EE85	Uncharacterized protein.	Uncharacterized protein.	0.553
MAC_00349	MAC_00498	E9DRI0	E9DSA0	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	Telomere-binding alpha subunit central domain-containing protein.	0.783
MAC_00349	MAC_00758	E9DRI0	E9DTC0	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	PUA domain-containing protein.	0.999
MAC_00349	MAC_01263	E9DRI0	E9DUG5	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	WD repeat-containing protein 79.	0.978
MAC_00349	MAC_05126	E9DRI0	E9E5H8	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	H/ACA ribonucleoprotein complex subunit 3.	0.999
MAC_00349	MAC_05232	E9DRI0	E9E5T4	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	TruB family pseudouridylate synthase containing protein.	0.974
MAC_00349	MAC_05324	E9DRI0	E9E626	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.912
MAC_00349	MAC_09239	E9DRI0	E9EH91	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	H/ACA ribonucleoprotein complex subunit, putative.	0.999
MAC_00430	MAC_00607	E9DRR1	E9DSK9	Uncharacterized protein.	SNF2 family helicase/ATPase.	0.439
MAC_00430	MAC_05651	E9DRR1	E9E715	Uncharacterized protein.	Sister chromatid cohesion protein Ctf8, putative.	0.999