(46 nodes) DNA Damage Bypass network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_08740	DNA replication factor A subunit Ssb3. (101 aa)
	MAC_00616	Zinc finger protein. (82 aa)
	MAC_00683	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (351 aa)
	MAC_01259	DNA damage-binding protein 1. (1121 aa)
	MAC_01309	AAA family ATPase. (756 aa)
	MAC_01509	Uncharacterized protein. (143 aa)
	MAC_01557	Ubiquitin fusion degradation protein (Ufd1), putative. (757 aa)
	MAC_01614	Telomere length regulation protein elg1. (1191 aa)
	MAC_01846	WD repeat protein. (996 aa)
	MAC_01865	DNA polymerase kappa. (501 aa)
	MAC_01896	RING-A protein. (103 aa)
	MAC_01946	Ubiquitin. (153 aa)
	MAC_00150	Pol protein. (217 aa)
	MAC_02019	UDP-galactopyranose mutase. (548 aa)
	MAC_02102	WD domain protein. (740 aa)
	MAC_02547	Ubiquitin ligase subunit CulD; Belongs to the cullin family. (835 aa)
	MAC_02642	Ubiquitin. (343 aa)
	MAC_02651	Ubiquitin carboxyl-terminal hydrolase 2; Belongs to the peptidase C19 family. (1031 aa)
	MAC_02655	CHY zinc finger domain protein. (691 aa)
	MAC_02765	Pol protein. (874 aa)
	MAC_02768	Uncharacterized protein. (215 aa)
	MAC_02820	Fungal specific transcription factor, putative. (130 aa)
	MAC_03113	Ubiquitin carboxyl-terminal hydrolase; Belongs to the peptidase C19 family. (1602 aa)
	MAC_03387	Telomere silencing protein Zds1, putative. (992 aa)
	MAC_03634	DNA polymerase delta subunit 4. (200 aa)
	MAC_03823	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (595 aa)
	MAC_04324	TPR Domain containing protein. (550 aa)
	MAC_04569	Gag protein. (541 aa)
	MAC_05331	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1139 aa)
	MAC_05357	DNA polymerase. (1677 aa)
	MAC_05369	Sister chromatid cohesion protein Eso1. (585 aa)
	MAC_06514	UmuC domain-containing protein. (548 aa)
	MAC_06646	Pol protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (868 aa)
	MAC_06647	Pol protein. (231 aa)
	MAC_06747	Histone-like transcription factor and archaeal histone family protein. (194 aa)
	MAC_07468	CCHC-type domain-containing protein. (206 aa)
	MAC_07542	Ubiquitin carboxyl-terminal hydrolase. (833 aa)
	MAC_07842	Zn(2)-C6 fungal-type domain-containing protein. (224 aa)
	MAC_08183	Uncharacterized protein. (438 aa)
	MAC_08184	Postreplication repair protein uvsH/nuvA. (462 aa)
	MAC_09841	Complex I intermediate-associated protein 30. (227 aa)
	MAC_09433	CHY and RING finger domain protein, putative. (514 aa)
	MAC_08284	BZIP domain-containing protein. (257 aa)
	MAC_00428	REV7-like protein. (274 aa)
	MAC_00571	Ubiquitin carboxyl-terminal hydrolase 12; Belongs to the peptidase C19 family. (645 aa)
	MAC_08697	Uncharacterized protein. (1695 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00150	MAC_02765	E9DQY1	E9DYR7	Pol protein.	Pol protein.	0.951
MAC_00150	MAC_03823	E9DQY1	E9E1W8	Pol protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.423
MAC_00150	MAC_06646	E9DQY1	E9E9U8	Pol protein.	Pol protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.950
MAC_00150	MAC_06647	E9DQY1	E9E9U9	Pol protein.	Pol protein.	0.939
MAC_00428	MAC_00683	E9DRQ9	E9DST5	REV7-like protein.	Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.	0.569
MAC_00428	MAC_01614	E9DRQ9	E9DVG6	REV7-like protein.	Telomere length regulation protein elg1.	0.618
MAC_00428	MAC_01865	E9DRQ9	E9DW67	REV7-like protein.	DNA polymerase kappa.	0.888
MAC_00428	MAC_01946	E9DRQ9	E9DWE8	REV7-like protein.	Ubiquitin.	0.534
MAC_00428	MAC_02642	E9DRQ9	E9DYE5	REV7-like protein.	Ubiquitin.	0.612
MAC_00428	MAC_02768	E9DRQ9	E9DYS0	REV7-like protein.	Uncharacterized protein.	0.910
MAC_00428	MAC_03823	E9DRQ9	E9E1W8	REV7-like protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.616
MAC_00428	MAC_05331	E9DRQ9	E9E633	REV7-like protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.935
MAC_00428	MAC_05357	E9DRQ9	E9E659	REV7-like protein.	DNA polymerase.	0.999
MAC_00428	MAC_05369	E9DRQ9	E9E671	REV7-like protein.	Sister chromatid cohesion protein Eso1.	0.962
MAC_00428	MAC_06514	E9DRQ9	E9E9G6	REV7-like protein.	UmuC domain-containing protein.	0.905
MAC_00428	MAC_07842	E9DRQ9	E9ED94	REV7-like protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.910
MAC_00428	MAC_08183	E9DRQ9	E9EE85	REV7-like protein.	Uncharacterized protein.	0.946
MAC_00428	MAC_08184	E9DRQ9	E9EE86	REV7-like protein.	Postreplication repair protein uvsH/nuvA.	0.635
MAC_00428	MAC_08284	E9DRQ9	E9EEI6	REV7-like protein.	BZIP domain-containing protein.	0.534
MAC_00428	MAC_09841	E9DRQ9	E9EIZ3	REV7-like protein.	Complex I intermediate-associated protein 30.	0.534