(47 nodes) Clathrin-mediated endocytosis network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00642	Uncharacterized protein. (690 aa)
	MAC_09841	Complex I intermediate-associated protein 30. (227 aa)
	MAC_09619	Adaptin ear-binding coat-associated protein 2. (262 aa)
	MAC_09421	COP9 signalosome subunit 6 (CsnF), putative. (418 aa)
	MAC_08566	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (237 aa)
	MAC_08529	Vacuolar sorting receptor (Mrl1), putative. (379 aa)
	MAC_08284	BZIP domain-containing protein. (257 aa)
	MAC_07888	UBA/TS-N domain-containing protein. (909 aa)
	MAC_07821	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1683 aa)
	MAC_07657	Putative zinc finger, FYVE domain containing protein. (338 aa)
	MAC_07617	COP9 signalosome subunit 7 (CsnG). (282 aa)
	MAC_07485	Deubiquitination-protection protein dph1. (441 aa)
	MAC_07299	MFS multidrug transporter, putative. (423 aa)
	MAC_07284	Uncharacterized protein. (331 aa)
	MAC_07086	Heat shock protein 78; Belongs to the ClpA/ClpB family. (789 aa)
	MAC_06905	Putative budding protein BOI2. (944 aa)
	MAC_06872	COP9 signalosome subunit 2 (CsnB), putative. (508 aa)
	MAC_05614	EF hand domain protein. (1207 aa)
	MAC_05555	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (436 aa)
	MAC_05472	Epsin domain containing protein. (456 aa)
	MAC_05353	ANTH domain protein. (1016 aa)
	MAC_05281	NEDD8-like protein (RubA). (545 aa)
	MAC_05066	MFS amine transporter, putative. (363 aa)
	MAC_05034	Heat shock protein 101; Belongs to the ClpA/ClpB family. (926 aa)
	MAC_04948	Actin polymerization protein Bzz1, putative. (804 aa)
	MAC_04647	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (751 aa)
	MAC_04335	COP9 signalosome complex subunit 3. (489 aa)
	MAC_04011	ENTH domain containing protein. (617 aa)
	MAC_03437	Cell division control protein (Cdc15), putative. (882 aa)
	MAC_03428	Epsin-like protein ent1/2. (550 aa)
	MAC_03142	PolyA nuclease. (1424 aa)
	MAC_02915	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (981 aa)
	MAC_02811	Serine/threonine protein kinase. (1022 aa)
	MAC_02650	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (755 aa)
	MAC_02642	Ubiquitin. (343 aa)
	MAC_02422	Rho-GTPase-activating protein 8. (841 aa)
	MAC_02050	Osmosensor protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (306 aa)
	MAC_02011	Uncharacterized protein. (464 aa)
	MAC_01946	Ubiquitin. (153 aa)
	MAC_01491	Phosphatidylinositol-4-phosphate 5-kinase its3. (961 aa)
	MAC_00912	WASP-like pretein las17p. (682 aa)
	MAC_00689	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
	MAC_00663	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (731 aa)
	MAC_00662	Rad60-SLD_2 domain-containing protein. (267 aa)
	MAC_00650	Eps15-like protein pan1p. (397 aa)
	MAC_00253	Fes/CIP4 domain-containing protein. (896 aa)
	MAC_00202	Synaptobrevin. (124 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00202	MAC_00662	E9DR33	E9DSR4	Synaptobrevin.	Rad60-SLD_2 domain-containing protein.	0.485
MAC_00202	MAC_00663	E9DR33	E9DSR5	Synaptobrevin.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.485
MAC_00202	MAC_00689	E9DR33	E9DSU1	Synaptobrevin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.659
MAC_00202	MAC_01946	E9DR33	E9DWE8	Synaptobrevin.	Ubiquitin.	0.415
MAC_00202	MAC_02011	E9DR33	E9DWL3	Synaptobrevin.	Uncharacterized protein.	0.631
MAC_00202	MAC_02642	E9DR33	E9DYE5	Synaptobrevin.	Ubiquitin.	0.412
MAC_00202	MAC_02650	E9DR33	E9DYF3	Synaptobrevin.	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.	0.536
MAC_00202	MAC_02915	E9DR33	E9DZ67	Synaptobrevin.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.555
MAC_00202	MAC_03428	E9DR33	E9E0N0	Synaptobrevin.	Epsin-like protein ent1/2.	0.602
MAC_00202	MAC_04011	E9DR33	E9E2B3	Synaptobrevin.	ENTH domain containing protein.	0.891
MAC_00202	MAC_04647	E9DR33	E9E449	Synaptobrevin.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.485
MAC_00202	MAC_05066	E9DR33	E9E597	Synaptobrevin.	MFS amine transporter, putative.	0.651
MAC_00202	MAC_05353	E9DR33	E9E655	Synaptobrevin.	ANTH domain protein.	0.631
MAC_00202	MAC_05472	E9DR33	E9E6H4	Synaptobrevin.	Epsin domain containing protein.	0.602
MAC_00202	MAC_05555	E9DR33	E9E6Q7	Synaptobrevin.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.632
MAC_00202	MAC_06905	E9DR33	E9EAK7	Synaptobrevin.	Putative budding protein BOI2.	0.484
MAC_00202	MAC_07284	E9DR33	E9EBN6	Synaptobrevin.	Uncharacterized protein.	0.536
MAC_00202	MAC_07299	E9DR33	E9EBQ1	Synaptobrevin.	MFS multidrug transporter, putative.	0.651
MAC_00202	MAC_07485	E9DR33	E9EC87	Synaptobrevin.	Deubiquitination-protection protein dph1.	0.484
MAC_00202	MAC_07657	E9DR33	E9ECQ9	Synaptobrevin.	Putative zinc finger, FYVE domain containing protein.	0.536