(27 nodes) RHOA GTPase cycle network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_07948	UBX domain protein. (537 aa)
	MAC_07712	Uncharacterized protein. (729 aa)
	MAC_07622	Ras GTPase activating protein. (1676 aa)
	MAC_07455	Suaprga1-like protein. (294 aa)
	MAC_07416	Uncharacterized protein. (789 aa)
	MAC_07403	Morphogenesis protein (Msb1), putative. (1005 aa)
	MAC_07052	SNARE docking complex subunit; Belongs to the STXBP/unc-18/SEC1 family. (702 aa)
	MAC_06774	Phospholipase. (879 aa)
	MAC_06497	Integral membrane protein (Ptm1). (459 aa)
	MAC_05358	SMP-LTD domain-containing protein. (1006 aa)
	MAC_00935	Beta-chimaerin. (755 aa)
	MAC_00815	Rho guanyl nucleotide exchange factor (Rom2), putative. (1246 aa)
	MAC_01151	Phospholipase. (1838 aa)
	MAC_01327	RhoGAP domain containing protein. (985 aa)
	MAC_01428	RHO protein GDP dissociation inhibitor containing protein. (198 aa)
	MAC_05223	Actin. (375 aa)
	MAC_05155	Importin 11, putative. (1040 aa)
	MAC_04995	Rho GTPase activator (Sac7), putative. (898 aa)
	MAC_04857	Uncharacterized protein. (151 aa)
	MAC_04584	Plasma membrane SNARE protein (Sec9), putative. (444 aa)
	MAC_04247	RhoGAP domain protein. (1313 aa)
	MAC_03999	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1142 aa)
	MAC_03937	Cytokinesis protein. (1685 aa)
	MAC_03329	Uncharacterized protein. (366 aa)
	MAC_01740	Uncharacterized protein. (480 aa)
	MAC_09323	ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family. (234 aa)
	MAC_08514	Flotillin domain containing protein; Belongs to the band 7/mec-2 family. Flotillin subfamily. (561 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00815	MAC_00935	E9DTH7	E9DT53	Rho guanyl nucleotide exchange factor (Rom2), putative.	Beta-chimaerin.	0.424
MAC_00815	MAC_03999	E9DTH7	E9E2A1	Rho guanyl nucleotide exchange factor (Rom2), putative.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.730
MAC_00815	MAC_04995	E9DTH7	E9E5B9	Rho guanyl nucleotide exchange factor (Rom2), putative.	Rho GTPase activator (Sac7), putative.	0.484
MAC_00815	MAC_05223	E9DTH7	E9E5S5	Rho guanyl nucleotide exchange factor (Rom2), putative.	Actin.	0.450
MAC_00935	MAC_00815	E9DT53	E9DTH7	Beta-chimaerin.	Rho guanyl nucleotide exchange factor (Rom2), putative.	0.424
MAC_00935	MAC_01327	E9DT53	E9DUM9	Beta-chimaerin.	RhoGAP domain containing protein.	0.994
MAC_00935	MAC_01740	E9DT53	E9DVU2	Beta-chimaerin.	Uncharacterized protein.	0.405
MAC_00935	MAC_03329	E9DT53	E9E0D1	Beta-chimaerin.	Uncharacterized protein.	0.405
MAC_00935	MAC_03999	E9DT53	E9E2A1	Beta-chimaerin.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.479
MAC_00935	MAC_04247	E9DT53	E9E2Z9	Beta-chimaerin.	RhoGAP domain protein.	0.509
MAC_00935	MAC_04995	E9DT53	E9E5B9	Beta-chimaerin.	Rho GTPase activator (Sac7), putative.	0.405
MAC_00935	MAC_07622	E9DT53	E9ECM4	Beta-chimaerin.	Ras GTPase activating protein.	0.668
MAC_01151	MAC_04584	E9DU53	E9E3Y6	Phospholipase.	Plasma membrane SNARE protein (Sec9), putative.	0.519
MAC_01151	MAC_06774	E9DU53	E9EA76	Phospholipase.	Phospholipase.	0.907
MAC_01327	MAC_00935	E9DUM9	E9DT53	RhoGAP domain containing protein.	Beta-chimaerin.	0.994
MAC_01327	MAC_01428	E9DUM9	E9DV38	RhoGAP domain containing protein.	RHO protein GDP dissociation inhibitor containing protein.	0.647
MAC_01327	MAC_01740	E9DUM9	E9DVU2	RhoGAP domain containing protein.	Uncharacterized protein.	0.773
MAC_01327	MAC_03329	E9DUM9	E9E0D1	RhoGAP domain containing protein.	Uncharacterized protein.	0.773
MAC_01327	MAC_03937	E9DUM9	E9E239	RhoGAP domain containing protein.	Cytokinesis protein.	0.939
MAC_01327	MAC_03999	E9DUM9	E9E2A1	RhoGAP domain containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.569