(33 nodes) Selective autophagy network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_04744	Fungal specific transcription factor, putative. (696 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (552 aa)
	MAC_03903	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (254 aa)
	MAC_03904	Cell surface protein, putative. (467 aa)
	MAC_04203	Putative peroxisomal targeting signal receptor. (650 aa)
	MAC_04364	Dynein family protein. (519 aa)
	MAC_04729	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (343 aa)
	MAC_04837	Ubiquitin-conjugating enzyme E2 13; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
	MAC_04998	Serine/threonine-protein kinase. (948 aa)
	MAC_05227	Mitochondrial import receptor subunit TOM40. (377 aa)
	MAC_05892	ThiJ/PfpI family protein. (316 aa)
	MAC_06138	ThiJ/PfpI family protein. (185 aa)
	MAC_06410	Mitochondrial import receptor subunit tom-20. (196 aa)
	MAC_06731	ThiJ/PfpI family protein. (291 aa)
	MAC_07123	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (256 aa)
	MAC_07285	Casein kinase II, alpha chain (CK II alpha subunit); Belongs to the protein kinase superfamily. (427 aa)
	MAC_07322	ThiJ/PfpI family protein. (216 aa)
	MAC_08034	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (744 aa)
	MAC_08284	BZIP domain-containing protein. (257 aa)
	MAC_08764	Autophagy-related protein. (108 aa)
	MAC_08950	Ubiquitin hydrolase. (720 aa)
	MAC_09676	ThiJ/PfpI family protein. (217 aa)
	MAC_09841	Complex I intermediate-associated protein 30. (227 aa)
	MAC_01142	ZZ type zinc finger domain-containing protein. (865 aa)
	MAC_01160	Mitochondrial outer membrane 72kDa protein. (622 aa)
	MAC_01647	Mitochondrial import receptor subunit tom-22. (153 aa)
	MAC_01946	Ubiquitin. (153 aa)
	MAC_02545	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability. (2887 aa)
	MAC_02642	Ubiquitin. (343 aa)
	MAC_02739	Autophagy-related ubiquitin-like modifier atg-12. (121 aa)
	MAC_02750	Ubiquitin-conjugating enzyme spm2, putative. (120 aa)
	MAC_03427	Centrin. (216 aa)
	MAC_03681	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (895 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_01142	MAC_01946	E9DU44	E9DWE8	ZZ type zinc finger domain-containing protein.	Ubiquitin.	0.817
MAC_01142	MAC_02642	E9DU44	E9DYE5	ZZ type zinc finger domain-containing protein.	Ubiquitin.	0.691
MAC_01142	MAC_02739	E9DU44	E9DYP2	ZZ type zinc finger domain-containing protein.	Autophagy-related ubiquitin-like modifier atg-12.	0.858
MAC_01142	MAC_03681	E9DU44	E9E1D3	ZZ type zinc finger domain-containing protein.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.636
MAC_01142	MAC_03903	E9DU44	E9E1T5	ZZ type zinc finger domain-containing protein.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.782
MAC_01142	MAC_03904	E9DU44	E9E1T6	ZZ type zinc finger domain-containing protein.	Cell surface protein, putative.	0.782
MAC_01142	MAC_04203	E9DU44	E9E2V5	ZZ type zinc finger domain-containing protein.	Putative peroxisomal targeting signal receptor.	0.852
MAC_01142	MAC_04998	E9DU44	E9E5C2	ZZ type zinc finger domain-containing protein.	Serine/threonine-protein kinase.	0.438
MAC_01142	MAC_08034	E9DU44	E9EDT6	ZZ type zinc finger domain-containing protein.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.636
MAC_01142	MAC_08284	E9DU44	E9EEI6	ZZ type zinc finger domain-containing protein.	BZIP domain-containing protein.	0.817
MAC_01142	MAC_08764	E9DU44	E9EFW6	ZZ type zinc finger domain-containing protein.	Autophagy-related protein.	0.931
MAC_01142	MAC_09841	E9DU44	E9EIZ3	ZZ type zinc finger domain-containing protein.	Complex I intermediate-associated protein 30.	0.817
MAC_01160	MAC_01647	E9DU62	E9DVJ9	Mitochondrial outer membrane 72kDa protein.	Mitochondrial import receptor subunit tom-22.	0.980
MAC_01160	MAC_03681	E9DU62	E9E1D3	Mitochondrial outer membrane 72kDa protein.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.404
MAC_01160	MAC_05227	E9DU62	E9E5S9	Mitochondrial outer membrane 72kDa protein.	Mitochondrial import receptor subunit TOM40.	0.978
MAC_01160	MAC_06410	E9DU62	E9E962	Mitochondrial outer membrane 72kDa protein.	Mitochondrial import receptor subunit tom-20.	0.994
MAC_01160	MAC_08034	E9DU62	E9EDT6	Mitochondrial outer membrane 72kDa protein.	GTPase FZO1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.404
MAC_01160	MAC_08950	E9DU62	E9EGF2	Mitochondrial outer membrane 72kDa protein.	Ubiquitin hydrolase.	0.716
MAC_01647	MAC_01160	E9DVJ9	E9DU62	Mitochondrial import receptor subunit tom-22.	Mitochondrial outer membrane 72kDa protein.	0.980
MAC_01647	MAC_05227	E9DVJ9	E9E5S9	Mitochondrial import receptor subunit tom-22.	Mitochondrial import receptor subunit TOM40.	0.999