(32 nodes) Nervous system development network (Metarhizium acridum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAC_00065	Uncharacterized protein. (224 aa)
	MAC_00098	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)
	MAC_00662	Rad60-SLD_2 domain-containing protein. (267 aa)
	MAC_00663	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (731 aa)
	MAC_00689	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (143 aa)
	MAC_00912	WASP-like pretein las17p. (682 aa)
	MAC_01979	Amidohydro-rel domain-containing protein. (384 aa)
	MAC_02314	MAP kinase kinase EMK1. (506 aa)
	MAC_02479	Amidohydrolase. (303 aa)
	MAC_02642	Ubiquitin. (343 aa)
	MAC_02804	Uncharacterized protein. (144 aa)
	MAC_02915	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (981 aa)
	MAC_03304	Uncharacterized protein. (652 aa)
	MAC_00396	PH domain-containing protein. (411 aa)
	MAC_06129	Putative hydrolase. (357 aa)
	MAC_09598	Homeobox transcription factor, putative. (295 aa)
	MAC_09573	Cofilin, putative; Belongs to the actin-binding proteins ADF family. (134 aa)
	MAC_09062	Allantoinase. (526 aa)
	MAC_09026	Protein kinase domain-containing protein. (93 aa)
	MAC_08726	Uncharacterized protein. (137 aa)
	MAC_08566	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (237 aa)
	MAC_08361	Uncharacterized protein. (199 aa)
	MAC_08116	Tryptophanase. (918 aa)
	MAC_07821	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1683 aa)
	MAC_03315	Uncharacterized protein. (436 aa)
	MAC_07582	RacA. (214 aa)
	MAC_06599	Putative Cutinase transcription factor 1 alpha. (882 aa)
	MAC_06184	Uncharacterized protein. (739 aa)
	MAC_04647	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (751 aa)
	MAC_04869	Mitogen activated protein kinase kinase. (658 aa)
	MAC_05487	Protein kinase domain-containing protein. (728 aa)
	MAC_05555	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (436 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAC_00065	MAC_00098	E9DRZ2	E9DS25	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.479
MAC_00098	MAC_00065	E9DS25	E9DRZ2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.479
MAC_00098	MAC_00689	E9DS25	E9DSU1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.420
MAC_00098	MAC_02314	E9DS25	E9DXG6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	MAP kinase kinase EMK1.	0.998
MAC_00098	MAC_03304	E9DS25	E9E028	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.479
MAC_00098	MAC_03315	E9DS25	E9E039	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.479
MAC_00098	MAC_04869	E9DS25	E9E4S1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen activated protein kinase kinase.	0.855
MAC_00098	MAC_05487	E9DS25	E9E6I9	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.539
MAC_00098	MAC_05555	E9DS25	E9E6Q7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.424
MAC_00098	MAC_06184	E9DS25	E9E8I6	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Uncharacterized protein.	0.479
MAC_00098	MAC_07582	E9DS25	E9ECI4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	RacA.	0.511
MAC_00098	MAC_07821	E9DS25	E9ED73	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.420
MAC_00098	MAC_08566	E9DS25	E9EFB8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.417
MAC_00098	MAC_09026	E9DS25	E9EGM8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Protein kinase domain-containing protein.	0.479
MAC_00396	MAC_07582	E9DRM7	E9ECI4	PH domain-containing protein.	RacA.	0.422
MAC_00396	MAC_07821	E9DRM7	E9ED73	PH domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.572
MAC_00662	MAC_00689	E9DSR4	E9DSU1	Rad60-SLD_2 domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.907
MAC_00662	MAC_02642	E9DSR4	E9DYE5	Rad60-SLD_2 domain-containing protein.	Ubiquitin.	0.552
MAC_00662	MAC_02915	E9DSR4	E9DZ67	Rad60-SLD_2 domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.800
MAC_00662	MAC_05555	E9DSR4	E9E6Q7	Rad60-SLD_2 domain-containing protein.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.917