(9 nodes) Biotin metabolism network (Metarhizium acridum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	MAC_01735	Uncharacterized protein. (651 aa)
	MAC_01736	Aminotransferase, putative. (451 aa)
	MAC_01737	Biotin synthase, putative. (419 aa)
	MAC_02269	3-oxoacyl-(Acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa)
	MAC_03637	Carbonyl reductase 4. (173 aa)
	MAC_04795	Biotin apo-protein ligase, putative. (670 aa)
	MAC_08668	3-oxoacyl-[acyl-carrier-protein]-synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (389 aa)
	Arp2	Hydroxynaphthalene reductase-like protein Arp2; Hydroxynaphthalene reductase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster. The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified. (267 aa)
	MAC_09347	3-ketoacyl-acyl carrier protein reductase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)

Your Current Organism:

Metarhizium acridum

NCBI taxonomy Id: 655827
Other names: M. acridum CQMa 102, Metarhizium acridum CQMa 102, Metarhizium anisopliae var. acridum CQMa 102

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arp2	MAC_02269	E9EHG1	E9DXC1	Hydroxynaphthalene reductase-like protein Arp2; Hydroxynaphthalene reductase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster. The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified.	3-oxoacyl-(Acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.908
Arp2	MAC_03637	E9EHG1	E9E189	Hydroxynaphthalene reductase-like protein Arp2; Hydroxynaphthalene reductase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster. The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified.	Carbonyl reductase 4.	0.908
Arp2	MAC_08668	E9EHG1	E9EFM0	Hydroxynaphthalene reductase-like protein Arp2; Hydroxynaphthalene reductase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster. The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified.	3-oxoacyl-[acyl-carrier-protein]-synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.932
Arp2	MAC_09347	E9EHG1	E9EHJ9	Hydroxynaphthalene reductase-like protein Arp2; Hydroxynaphthalene reductase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster. The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified.	3-ketoacyl-acyl carrier protein reductase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.908
MAC_01735	MAC_01736	E9DVT7	E9DVT8	Uncharacterized protein.	Aminotransferase, putative.	0.949
MAC_01735	MAC_01737	E9DVT7	E9DVT9	Uncharacterized protein.	Biotin synthase, putative.	0.995
MAC_01736	MAC_01735	E9DVT8	E9DVT7	Aminotransferase, putative.	Uncharacterized protein.	0.949
MAC_01736	MAC_01737	E9DVT8	E9DVT9	Aminotransferase, putative.	Biotin synthase, putative.	0.947
MAC_01737	MAC_01735	E9DVT9	E9DVT7	Biotin synthase, putative.	Uncharacterized protein.	0.995
MAC_01737	MAC_01736	E9DVT9	E9DVT8	Biotin synthase, putative.	Aminotransferase, putative.	0.947
MAC_01737	MAC_04795	E9DVT9	E9E4J7	Biotin synthase, putative.	Biotin apo-protein ligase, putative.	0.952
MAC_01737	MAC_08668	E9DVT9	E9EFM0	Biotin synthase, putative.	3-oxoacyl-[acyl-carrier-protein]-synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.595
MAC_02269	Arp2	E9DXC1	E9EHG1	3-oxoacyl-(Acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hydroxynaphthalene reductase-like protein Arp2; Hydroxynaphthalene reductase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster. The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified.	0.908
MAC_02269	MAC_03637	E9DXC1	E9E189	3-oxoacyl-(Acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Carbonyl reductase 4.	0.900
MAC_02269	MAC_08668	E9DXC1	E9EFM0	3-oxoacyl-(Acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	3-oxoacyl-[acyl-carrier-protein]-synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.939
MAC_02269	MAC_09347	E9DXC1	E9EHJ9	3-oxoacyl-(Acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	3-ketoacyl-acyl carrier protein reductase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.908
MAC_03637	Arp2	E9E189	E9EHG1	Carbonyl reductase 4.	Hydroxynaphthalene reductase-like protein Arp2; Hydroxynaphthalene reductase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster. The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified.	0.908
MAC_03637	MAC_02269	E9E189	E9DXC1	Carbonyl reductase 4.	3-oxoacyl-(Acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.900
MAC_03637	MAC_08668	E9E189	E9EFM0	Carbonyl reductase 4.	3-oxoacyl-[acyl-carrier-protein]-synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.979
MAC_03637	MAC_09347	E9E189	E9EHJ9	Carbonyl reductase 4.	3-ketoacyl-acyl carrier protein reductase, putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.908