(33 nodes) Mixed, incl. DNA damage checkpoint signaling, and HDR through Single Strand Annealing (SSA) network (Grosmannia clavigera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMQ_3625	Meiotic recombination protein mre11. (1249 aa)
	CMQ_3710	DNA/RNA helicase. (1854 aa)
	CMQ_3380	Rad51 domain-containing protein. (333 aa)
	CMQ_4017	ATP-dependent DNA helicase. (1099 aa)
	CMQ_4105	Flap structure-specific endonuclease. (749 aa)
	CMQ_4048	DNA repair protein. (498 aa)
	CMQ_1680	Cell cycle checkpoint protein. (579 aa)
	CMQ_1609	BRCT domain-containing protein. (1278 aa)
	CMQ_1365	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (354 aa)
	CMQ_1119	3-5 exonuclease helicase. (525 aa)
	CMQ_654	Exodeoxyribonuclease 1. (805 aa)
	CMQ_740	DNA repair protein. (451 aa)
	CMQ_728	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (631 aa)
	CMQ_1531	Rad52 DNA repair protein radc. (535 aa)
	CMQ_5427	Brct domain containing protein. (901 aa)
	CMQ_2970	DNA damage repair protein. (989 aa)
	CMQ_2848	MRC1 domain-containing protein. (1439 aa)
	CMQ_2506	Dead box helicase. (1329 aa)
	CMQ_2475	DNA damage response protein. (833 aa)
	CMQ_2430	DNA repair protein. (212 aa)
	CMQ_5044	Inositol kinase kinase; Belongs to the PI3/PI4-kinase family. (2089 aa)
	CMQ_8095	Serine/threonine-protein kinase chk2. (728 aa)
	CMQ_5945	DNA replication helicase. (1602 aa)
	CMQ_1997	DNA repair protein. (356 aa)
	CMQ_2022	Mediated genome instability protein rmi1. (240 aa)
	CMQ_7431	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (636 aa)
	CMQ_347	DNA excision repair protein. (1181 aa)
	CMQ_135	Hmg-i/hmg-y, DNA-binding protein. (1274 aa)
	CMQ_234	DNA repair and recombination protein rad54. (809 aa)
	CMQ_7794	Phosphotidylinositol kinase; Belongs to the PI3/PI4-kinase family. (3892 aa)
	CMQ_7775	Serine/threonine-protein kinase-like protein. (1347 aa)
	CMQ_4653	DNA repair protein rad50. (1301 aa)
	CMQ_4781	Putative replication factor-a protein. (278 aa)

Your Current Organism:

Grosmannia clavigera

NCBI taxonomy Id: 655863
Other names: G. clavigera kw1407, Grosmannia clavigera kw1407

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMQ_1119	CMQ_135	F0XEG4	F0XR44	3-5 exonuclease helicase.	Hmg-i/hmg-y, DNA-binding protein.	0.995
CMQ_1119	CMQ_1365	F0XEG4	F0XDU4	3-5 exonuclease helicase.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.999
CMQ_1119	CMQ_1531	F0XEG4	F0XFN7	3-5 exonuclease helicase.	Rad52 DNA repair protein radc.	0.999
CMQ_1119	CMQ_1609	F0XEG4	F0XDH1	3-5 exonuclease helicase.	BRCT domain-containing protein.	0.996
CMQ_1119	CMQ_1680	F0XEG4	F0XD01	3-5 exonuclease helicase.	Cell cycle checkpoint protein.	0.993
CMQ_1119	CMQ_1997	F0XEG4	F0XN59	3-5 exonuclease helicase.	DNA repair protein.	0.993
CMQ_1119	CMQ_2022	F0XEG4	F0XND4	3-5 exonuclease helicase.	Mediated genome instability protein rmi1.	0.998
CMQ_1119	CMQ_234	F0XEG4	F0XRJ4	3-5 exonuclease helicase.	DNA repair and recombination protein rad54.	0.877
CMQ_1119	CMQ_2430	F0XEG4	F0XIX7	3-5 exonuclease helicase.	DNA repair protein.	0.992
CMQ_1119	CMQ_2475	F0XEG4	F0XIR8	3-5 exonuclease helicase.	DNA damage response protein.	0.995
CMQ_1119	CMQ_2506	F0XEG4	F0XI67	3-5 exonuclease helicase.	Dead box helicase.	0.975
CMQ_1119	CMQ_2848	F0XEG4	F0XGS6	3-5 exonuclease helicase.	MRC1 domain-containing protein.	0.644
CMQ_1119	CMQ_2970	F0XEG4	F0XG99	3-5 exonuclease helicase.	DNA damage repair protein.	0.912
CMQ_1119	CMQ_3380	F0XEG4	F0X948	3-5 exonuclease helicase.	Rad51 domain-containing protein.	0.999
CMQ_1119	CMQ_347	F0XEG4	F0XR15	3-5 exonuclease helicase.	DNA excision repair protein.	0.650
CMQ_1119	CMQ_3625	F0XEG4	F0X8Q5	3-5 exonuclease helicase.	Meiotic recombination protein mre11.	0.999
CMQ_1119	CMQ_3710	F0XEG4	F0X942	3-5 exonuclease helicase.	DNA/RNA helicase.	0.737
CMQ_1119	CMQ_4017	F0XEG4	F0X9I1	3-5 exonuclease helicase.	ATP-dependent DNA helicase.	0.967
CMQ_1119	CMQ_4048	F0XEG4	F0XA61	3-5 exonuclease helicase.	DNA repair protein.	0.998
CMQ_1119	CMQ_4105	F0XEG4	F0XA50	3-5 exonuclease helicase.	Flap structure-specific endonuclease.	0.999