(12 nodes) Mixed, incl. HDR through Single Strand Annealing (SSA), and Rhp55-Rhp57 complex network (Grosmannia clavigera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMQ_3710	DNA/RNA helicase. (1854 aa)
	CMQ_3380	Rad51 domain-containing protein. (333 aa)
	CMQ_4048	DNA repair protein. (498 aa)
	CMQ_1119	3-5 exonuclease helicase. (525 aa)
	CMQ_654	Exodeoxyribonuclease 1. (805 aa)
	CMQ_728	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (631 aa)
	CMQ_2506	Dead box helicase. (1329 aa)
	CMQ_5945	DNA replication helicase. (1602 aa)
	CMQ_2022	Mediated genome instability protein rmi1. (240 aa)
	CMQ_7431	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (636 aa)
	CMQ_135	Hmg-i/hmg-y, DNA-binding protein. (1274 aa)
	CMQ_4781	Putative replication factor-a protein. (278 aa)

Your Current Organism:

Grosmannia clavigera

NCBI taxonomy Id: 655863
Other names: G. clavigera kw1407, Grosmannia clavigera kw1407

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMQ_1119	CMQ_135	F0XEG4	F0XR44	3-5 exonuclease helicase.	Hmg-i/hmg-y, DNA-binding protein.	0.995
CMQ_1119	CMQ_2022	F0XEG4	F0XND4	3-5 exonuclease helicase.	Mediated genome instability protein rmi1.	0.998
CMQ_1119	CMQ_2506	F0XEG4	F0XI67	3-5 exonuclease helicase.	Dead box helicase.	0.975
CMQ_1119	CMQ_3380	F0XEG4	F0X948	3-5 exonuclease helicase.	Rad51 domain-containing protein.	0.999
CMQ_1119	CMQ_3710	F0XEG4	F0X942	3-5 exonuclease helicase.	DNA/RNA helicase.	0.737
CMQ_1119	CMQ_4048	F0XEG4	F0XA61	3-5 exonuclease helicase.	DNA repair protein.	0.998
CMQ_1119	CMQ_4781	F0XEG4	F0XUW4	3-5 exonuclease helicase.	Putative replication factor-a protein.	0.999
CMQ_1119	CMQ_5945	F0XEG4	F0XML5	3-5 exonuclease helicase.	DNA replication helicase.	0.996
CMQ_1119	CMQ_654	F0XEG4	F0XEI8	3-5 exonuclease helicase.	Exodeoxyribonuclease 1.	0.999
CMQ_1119	CMQ_728	F0XEG4	F0XFA7	3-5 exonuclease helicase.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.999
CMQ_1119	CMQ_7431	F0XEG4	F0XQ46	3-5 exonuclease helicase.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.999
CMQ_135	CMQ_1119	F0XR44	F0XEG4	Hmg-i/hmg-y, DNA-binding protein.	3-5 exonuclease helicase.	0.995
CMQ_135	CMQ_2022	F0XR44	F0XND4	Hmg-i/hmg-y, DNA-binding protein.	Mediated genome instability protein rmi1.	0.615
CMQ_135	CMQ_2506	F0XR44	F0XI67	Hmg-i/hmg-y, DNA-binding protein.	Dead box helicase.	0.413
CMQ_135	CMQ_3380	F0XR44	F0X948	Hmg-i/hmg-y, DNA-binding protein.	Rad51 domain-containing protein.	0.765
CMQ_135	CMQ_3710	F0XR44	F0X942	Hmg-i/hmg-y, DNA-binding protein.	DNA/RNA helicase.	0.945
CMQ_135	CMQ_4048	F0XR44	F0XA61	Hmg-i/hmg-y, DNA-binding protein.	DNA repair protein.	0.845
CMQ_135	CMQ_4781	F0XR44	F0XUW4	Hmg-i/hmg-y, DNA-binding protein.	Putative replication factor-a protein.	0.766
CMQ_135	CMQ_5945	F0XR44	F0XML5	Hmg-i/hmg-y, DNA-binding protein.	DNA replication helicase.	0.896
CMQ_135	CMQ_654	F0XR44	F0XEI8	Hmg-i/hmg-y, DNA-binding protein.	Exodeoxyribonuclease 1.	0.946