(23 nodes) DNA integrity checkpoint signaling network (Grosmannia clavigera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMQ_3625	Meiotic recombination protein mre11. (1249 aa)
	CMQ_5756	Serine/threonine-protein kinase. (573 aa)
	CMQ_7775	Serine/threonine-protein kinase-like protein. (1347 aa)
	CMQ_7794	Phosphotidylinositol kinase; Belongs to the PI3/PI4-kinase family. (3892 aa)
	CMQ_256	Brct domain containing protein. (758 aa)
	CMQ_1997	DNA repair protein. (356 aa)
	CMQ_8283	DNA repair protein. (614 aa)
	CMQ_8131	Cell division control protein; Belongs to the CDC6/cdc18 family. (694 aa)
	CMQ_8095	Serine/threonine-protein kinase chk2. (728 aa)
	CMQ_2104	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (526 aa)
	CMQ_2430	DNA repair protein. (212 aa)
	CMQ_2475	DNA damage response protein. (833 aa)
	CMQ_5896	Uncharacterized protein. (324 aa)
	CMQ_2504	Mitotic spindle checkpoint component mad2. (234 aa)
	CMQ_2848	MRC1 domain-containing protein. (1439 aa)
	CMQ_2773	Ubiquitin conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	CMQ_2970	DNA damage repair protein. (989 aa)
	CMQ_2682	Protein kinase. (1708 aa)
	CMQ_1183	Cell cycle protein. (471 aa)
	CMQ_1424	Cell cycle checkpoint protein. (979 aa)
	CMQ_1680	Cell cycle checkpoint protein. (579 aa)
	CMQ_1774	Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (309 aa)
	CMQ_6791	Alpha-mannosyltransferase. (865 aa)

Your Current Organism:

Grosmannia clavigera

NCBI taxonomy Id: 655863
Other names: G. clavigera kw1407, Grosmannia clavigera kw1407

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMQ_1183	CMQ_1424	F0XF44	F0XE05	Cell cycle protein.	Cell cycle checkpoint protein.	0.479
CMQ_1183	CMQ_1774	F0XF44	F0XB00	Cell cycle protein.	Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.593
CMQ_1183	CMQ_2430	F0XF44	F0XIX7	Cell cycle protein.	DNA repair protein.	0.444
CMQ_1183	CMQ_2504	F0XF44	F0XHS3	Cell cycle protein.	Mitotic spindle checkpoint component mad2.	0.490
CMQ_1183	CMQ_256	F0XF44	F0XR41	Cell cycle protein.	Brct domain containing protein.	0.657
CMQ_1183	CMQ_2848	F0XF44	F0XGS6	Cell cycle protein.	MRC1 domain-containing protein.	0.847
CMQ_1183	CMQ_5756	F0XF44	F0XT35	Cell cycle protein.	Serine/threonine-protein kinase.	0.870
CMQ_1183	CMQ_7775	F0XF44	F0XSC8	Cell cycle protein.	Serine/threonine-protein kinase-like protein.	0.990
CMQ_1183	CMQ_8095	F0XF44	F0XKJ8	Cell cycle protein.	Serine/threonine-protein kinase chk2.	0.919
CMQ_1183	CMQ_8131	F0XF44	F0XKN1	Cell cycle protein.	Cell division control protein; Belongs to the CDC6/cdc18 family.	0.850
CMQ_1424	CMQ_1183	F0XE05	F0XF44	Cell cycle checkpoint protein.	Cell cycle protein.	0.479
CMQ_1424	CMQ_1680	F0XE05	F0XD01	Cell cycle checkpoint protein.	Cell cycle checkpoint protein.	0.992
CMQ_1424	CMQ_1774	F0XE05	F0XB00	Cell cycle checkpoint protein.	Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.792
CMQ_1424	CMQ_1997	F0XE05	F0XN59	Cell cycle checkpoint protein.	DNA repair protein.	0.989
CMQ_1424	CMQ_2430	F0XE05	F0XIX7	Cell cycle checkpoint protein.	DNA repair protein.	0.995
CMQ_1424	CMQ_2475	F0XE05	F0XIR8	Cell cycle checkpoint protein.	DNA damage response protein.	0.815
CMQ_1424	CMQ_2504	F0XE05	F0XHS3	Cell cycle checkpoint protein.	Mitotic spindle checkpoint component mad2.	0.429
CMQ_1424	CMQ_256	F0XE05	F0XR41	Cell cycle checkpoint protein.	Brct domain containing protein.	0.872
CMQ_1424	CMQ_2848	F0XE05	F0XGS6	Cell cycle checkpoint protein.	MRC1 domain-containing protein.	0.735
CMQ_1424	CMQ_2970	F0XE05	F0XG99	Cell cycle checkpoint protein.	DNA damage repair protein.	0.826