(26 nodes) Chromosome Maintenance network (Grosmannia clavigera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (819 aa)
	CMQ_3021	Pseudouridine synthase. (510 aa)
	CMQ_2071	C6 zinc finger domain containing protein. (371 aa)
	CMQ_8096	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1100 aa)
	CMQ_8149	H aca ribonucleoprotein complex subunit 3. (61 aa)
	CMQ_5934	Telomere-binding alpha subunit central domain containing protein. (716 aa)
	CMQ_6255	Small nuclear ribonucleoprotein complex protein. (277 aa)
	CMQ_2010	Histone H2B; Belongs to the histone H2B family. (137 aa)
	CMQ_7736	Snf2 family helicase. (1741 aa)
	CMQ_1	Centromere microtubule-binding protein cbf5. (474 aa)
	CMQ_4552	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (470 aa)
	CMQ_4773	ATP-dependent DNA helicase; Belongs to the helicase family. (973 aa)
	CMQ_4788	Sister chromatid cohesion protein. (157 aa)
	CMQ_6578	DNA polymerase delta subunit. (197 aa)
	CMQ_4023	WD repeat-containing protein. (487 aa)
	CMQ_4214	Uncharacterized protein. (135 aa)
	CMQ_3679	Sister chromatid cohesion factor. (1061 aa)
	CMQ_3710	DNA/RNA helicase. (1854 aa)
	CMQ_3569	Cupin domain containing protein. (684 aa)
	CMQ_1024	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
	CMQ_718	Snf2 family helicase. (1138 aa)
	CMQ_1379	HD domain-containing protein. (257 aa)
	CMQ_1119	3-5 exonuclease helicase. (525 aa)
	CMQ_1444	Uncharacterized protein. (461 aa)
	CMQ_728	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (631 aa)
	CMQ_5421	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (179 aa)

Your Current Organism:

Grosmannia clavigera

NCBI taxonomy Id: 655863
Other names: G. clavigera kw1407, Grosmannia clavigera kw1407

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMQ_1	CMQ_1024	F0XRA9	F0XD51	Centromere microtubule-binding protein cbf5.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.893
CMQ_1	CMQ_1119	F0XRA9	F0XEG4	Centromere microtubule-binding protein cbf5.	3-5 exonuclease helicase.	0.471
CMQ_1	CMQ_1379	F0XRA9	F0XDX5	Centromere microtubule-binding protein cbf5.	HD domain-containing protein.	0.549
CMQ_1	CMQ_2071	F0XRA9	F0XJW7	Centromere microtubule-binding protein cbf5.	C6 zinc finger domain containing protein.	0.549
CMQ_1	CMQ_4023	F0XRA9	F0X8D9	Centromere microtubule-binding protein cbf5.	WD repeat-containing protein.	0.982
CMQ_1	CMQ_4552	F0XRA9	F0XTF8	Centromere microtubule-binding protein cbf5.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.910
CMQ_1	CMQ_4773	F0XRA9	F0XUJ8	Centromere microtubule-binding protein cbf5.	ATP-dependent DNA helicase; Belongs to the helicase family.	0.593
CMQ_1	CMQ_5421	F0XRA9	F0XG14	Centromere microtubule-binding protein cbf5.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.999
CMQ_1	CMQ_5934	F0XRA9	F0XLN0	Centromere microtubule-binding protein cbf5.	Telomere-binding alpha subunit central domain containing protein.	0.674
CMQ_1	CMQ_6255	F0XRA9	F0XM52	Centromere microtubule-binding protein cbf5.	Small nuclear ribonucleoprotein complex protein.	0.999
CMQ_1	CMQ_8096	F0XRA9	F0XKQ7	Centromere microtubule-binding protein cbf5.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.890
CMQ_1	CMQ_8149	F0XRA9	F0XL07	Centromere microtubule-binding protein cbf5.	H aca ribonucleoprotein complex subunit 3.	0.998
CMQ_1	PIF1	F0XRA9	F0XHJ8	Centromere microtubule-binding protein cbf5.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.593
CMQ_1024	CMQ_1	F0XD51	F0XRA9	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Centromere microtubule-binding protein cbf5.	0.893
CMQ_1024	CMQ_2010	F0XD51	F0XNI6	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Histone H2B; Belongs to the histone H2B family.	0.938
CMQ_1024	CMQ_3021	F0XD51	F0XIB8	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Pseudouridine synthase.	0.762
CMQ_1024	CMQ_4023	F0XD51	F0X8D9	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	WD repeat-containing protein.	0.444
CMQ_1024	CMQ_4552	F0XD51	F0XTF8	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.999
CMQ_1024	CMQ_6255	F0XD51	F0XM52	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Small nuclear ribonucleoprotein complex protein.	0.843
CMQ_1024	CMQ_718	F0XD51	F0XDW6	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	Snf2 family helicase.	0.721