(37 nodes) Sphingolipid metabolism network (Grosmannia clavigera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMQ_6152	Alkaline dihydroceramidase. (297 aa)
	EFM5	Protein-lysine N-methyltransferase EFM5; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that trimethylates elongation factor 1-alpha at 'Lys- 79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family. (244 aa)
	CMQ_7539	Integral membrane protein. (396 aa)
	CMQ_7519	Serine palmitoyltransferase. (657 aa)
	CMQ_7315	Ceramide synthase membrane component. (470 aa)
	CMQ_5687	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (294 aa)
	CMQ_5704	Alkaline ceramidase family protein. (343 aa)
	CMQ_5718	Beta-galactosidase. (1023 aa)
	CMQ_7804	Endopolyphosphatase; Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths. (702 aa)
	CMQ_8232	Ceramide glucosyltransferase. (541 aa)
	CMQ_7842	FA_desaturase domain-containing protein. (245 aa)
	CMQ_4883	3-ketosphinganine reductase. (350 aa)
	CMQ_4285	Sphinganine-1-phosphate aldolase. (586 aa)
	CMQ_5803	Neutral ceramidase. (795 aa)
	CMQ_7568	O-glycosyl hydrolase; Belongs to the glycosyl hydrolase 30 family. (494 aa)
	CMQ_1954	Sec14 cytosolic factor. (338 aa)
	CMQ_5947	Uncharacterized protein. (338 aa)
	CMQ_6892	Nmra-like protein. (328 aa)
	CMQ_6570	Sphingosine-1-phosphate phosphohydrolase. (574 aa)
	CMQ_6750	Alkaline ceramidase family protein. (258 aa)
	CMQ_4070	Cellular retinaldehyde-binding/triple function protein. (446 aa)
	CMQ_4119	Neutral ceramidase. (772 aa)
	CMQ_3802	Short chain dehydrogenase reductase. (291 aa)
	CMQ_5483	Beta-galactosidase. (108 aa)
	CMQ_1229	Beta-galactosidase; Belongs to the glycosyl hydrolase 2 family. (1096 aa)
	CMQ_1401	Endonuclease exonuclease phosphatase family protein. (442 aa)
	CMQ_384	Longevity-assurance protein 1. (398 aa)
	CMQ_1083	Longevity-assurance protein. (434 aa)
	CMQ_851	Serine palmitoyl transferase subunit. (522 aa)
	CMQ_1585	Sphingomyelinase family. (1091 aa)
	CMQ_5462	Integral membrane protein. (303 aa)
	CMQ_2679	Sphinganine hydroxylase; Belongs to the sterol desaturase family. (379 aa)
	CMQ_2992	Glycosyl hydrolase. (384 aa)
	CMQ_2117	Sphingosine kinase. (577 aa)
	CMQ_2435	C6 zinc finger domain containing protein. (542 aa)
	CMQ_2441	Beta-galactosidase. (584 aa)
	CMQ_5016	Longevity-assurance protein. (512 aa)

Your Current Organism:

Grosmannia clavigera

NCBI taxonomy Id: 655863
Other names: G. clavigera kw1407, Grosmannia clavigera kw1407

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMQ_1083	CMQ_1401	F0XDS9	F0XDD8	Longevity-assurance protein.	Endonuclease exonuclease phosphatase family protein.	0.532
CMQ_1083	CMQ_1585	F0XDS9	F0XF00	Longevity-assurance protein.	Sphingomyelinase family.	0.608
CMQ_1083	CMQ_2117	F0XDS9	F0XJE5	Longevity-assurance protein.	Sphingosine kinase.	0.608
CMQ_1083	CMQ_2679	F0XDS9	F0XGZ4	Longevity-assurance protein.	Sphinganine hydroxylase; Belongs to the sterol desaturase family.	0.649
CMQ_1083	CMQ_3802	F0XDS9	F0XA45	Longevity-assurance protein.	Short chain dehydrogenase reductase.	0.444
CMQ_1083	CMQ_4119	F0XDS9	F0X9I0	Longevity-assurance protein.	Neutral ceramidase.	0.576
CMQ_1083	CMQ_4883	F0XDS9	F0XUH2	Longevity-assurance protein.	3-ketosphinganine reductase.	0.809
CMQ_1083	CMQ_5687	F0XDS9	F0XSW6	Longevity-assurance protein.	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.	0.420
CMQ_1083	CMQ_5704	F0XDS9	F0XSU7	Longevity-assurance protein.	Alkaline ceramidase family protein.	0.619
CMQ_1083	CMQ_5803	F0XDS9	F0XSW7	Longevity-assurance protein.	Neutral ceramidase.	0.576
CMQ_1083	CMQ_6152	F0XDS9	F0XMI3	Longevity-assurance protein.	Alkaline dihydroceramidase.	0.619
CMQ_1083	CMQ_6570	F0XDS9	F0X7L5	Longevity-assurance protein.	Sphingosine-1-phosphate phosphohydrolase.	0.694
CMQ_1083	CMQ_6750	F0XDS9	F0X7V3	Longevity-assurance protein.	Alkaline ceramidase family protein.	0.564
CMQ_1083	CMQ_6892	F0XDS9	F0X742	Longevity-assurance protein.	Nmra-like protein.	0.604
CMQ_1083	CMQ_7568	F0XDS9	F0XP82	Longevity-assurance protein.	O-glycosyl hydrolase; Belongs to the glycosyl hydrolase 30 family.	0.511
CMQ_1083	CMQ_7804	F0XDS9	F0XSE1	Longevity-assurance protein.	Endopolyphosphatase; Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.	0.575
CMQ_1083	CMQ_7842	F0XDS9	F0XRV3	Longevity-assurance protein.	FA_desaturase domain-containing protein.	0.644
CMQ_1083	CMQ_8232	F0XDS9	F0XL14	Longevity-assurance protein.	Ceramide glucosyltransferase.	0.605
CMQ_1229	CMQ_2441	F0XCS9	F0XJW1	Beta-galactosidase; Belongs to the glycosyl hydrolase 2 family.	Beta-galactosidase.	0.516
CMQ_1401	CMQ_1083	F0XDD8	F0XDS9	Endonuclease exonuclease phosphatase family protein.	Longevity-assurance protein.	0.532