(71 nodes) 2-Oxocarboxylic acid metabolism network (Grosmannia clavigera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CMQ_6620	Vacuolar carboxypeptidase. (634 aa)
	CMQ_6725	Hmg-i/hmg-y, DNA-binding protein. (470 aa)
	CMQ_6607	Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (469 aa)
	CMQ_6650	Major facilitator superfamily transporter. (554 aa)
	CMQ_6646	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (786 aa)
	CMQ_6666	Uncharacterized protein. (352 aa)
	CMQ_7000	Aspartate aminotransferase. (437 aa)
	CMQ_6877	Aspartate aminotransferase. (432 aa)
	CMQ_6933	Mitochondrial acetolactate synthase small. (325 aa)
	CMQ_3510	Major facilitator superfamily transporter. (476 aa)
	CMQ_3943	Aspartate aminotransferase. (392 aa)
	CMQ_3731	Carboxypeptidase. (579 aa)
	CMQ_3651	Aspartokinase. (435 aa)
	CMQ_3412	Carboxypeptidase s. (601 aa)
	CMQ_4249	Isocitrate dehydrogenase. (363 aa)
	CMQ_3994	C6 zinc finger domain containing protein. (685 aa)
	CMQ_1787	Major facilitator superfamily transporter multidrug resistance. (558 aa)
	CMQ_5263	Succinyl-diaminopimelate desuccinylase. (416 aa)
	CMQ_5193	Tartrate dehydrogenase. (362 aa)
	CMQ_5157	C6 zinc finger domain containing protein. (1043 aa)
	CMQ_5252	Uncharacterized protein. (587 aa)
	CMQ_5251	Uncharacterized protein. (341 aa)
	CMQ_1056	Uncharacterized protein. (325 aa)
	CMQ_785	Major facilitator superfamily transporter. (680 aa)
	CMQ_624	Duf636 domain containing protein. (136 aa)
	CMQ_742	Heterokaryon incompatibility protein. (548 aa)
	CMQ_1367	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (423 aa)
	CMQ_1720	Uncharacterized protein. (594 aa)
	CMQ_1096	Major facilitator superfamily transporter multidrug resistance. (532 aa)
	CMQ_1647	Uncharacterized protein. (344 aa)
	CMQ_1163	Histidine acid phosphatase. (215 aa)
	CMQ_963	Dihydroxy-acid dehydratase. (707 aa)
	CMQ_746	Major facilitator superfamily transporter multidrug resistance. (591 aa)
	CMQ_1194	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (407 aa)
	CMQ_1214	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (786 aa)
	CMQ_1576	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (800 aa)
	CMQ_903	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (396 aa)
	CMQ_2578	Aromatic aminotransferase. (626 aa)
	CMQ_3080	Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (731 aa)
	CMQ_2665	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (381 aa)
	CMQ_2350	Major facilitator superfamily transporter. (630 aa)
	CMQ_2305	Aspartate-semialdehyde dehydrogenase. (371 aa)
	CMQ_2387	Acetylglutamate kinase. (390 aa)
	CMQ_2284	RNA cyclase; In the N-terminal section; belongs to the acetylglutamate kinase family. (880 aa)
	CMQ_4988	Peptidase. (158 aa)
	CMQ_5074	Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (424 aa)
	CMQ_4999	Citrate synthase; Belongs to the citrate synthase family. (480 aa)
	CMQ_8194	Major facilitator superfamily transporter multidrug resistance. (1129 aa)
	CMQ_8272	Vacuolar carboxypeptidase. (739 aa)
	CMQ_8291	Major facilitator superfamily transporter multidrug resistance. (561 aa)
	CMQ_8199	Acetolactate synthase. (598 aa)
	CMQ_6042	Major facilitator superfamily transporter. (620 aa)
	CMQ_5983	Uncharacterized protein. (906 aa)
	CMQ_6014	Alanine aminotransferase. (492 aa)
	CMQ_6258	Aromatic amino acid aminotransferase. (696 aa)
	CMQ_6313	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
	CMQ_6021	Uncharacterized protein. (221 aa)
	CMQ_7184	Vacuolar carboxypeptidase. (701 aa)
	CMQ_7089	Dihydroxy-acid dehydratase. (588 aa)
	CMQ_7118	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (1221 aa)
	CMQ_324	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (387 aa)
	CMQ_126	Acetylornithine deacetylase. (429 aa)
	CMQ_17	Branched-chain amino acid aminotransferase. (375 aa)
	CMQ_161	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (788 aa)
	CMQ_31	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (487 aa)
	CMQ_47	Nedd8-like protein. (77 aa)
	CMQ_5651	Aspartate aminotransferase. (420 aa)
	CMQ_5680	Major facilitator superfamily transporter. (623 aa)
	CMQ_4422	Citrate synthase; Belongs to the citrate synthase family. (473 aa)
	CMQ_4692	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (613 aa)
	CMQ_4605	Branched-chain amino acid aminotransferase. (221 aa)

Your Current Organism:

Grosmannia clavigera

NCBI taxonomy Id: 655863
Other names: G. clavigera kw1407, Grosmannia clavigera kw1407

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CMQ_1056	CMQ_1214	F0XCF1	F0XFI9	Uncharacterized protein.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.859
CMQ_1056	CMQ_1367	F0XCF1	F0XDV0	Uncharacterized protein.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.535
CMQ_1056	CMQ_1576	F0XCF1	F0XFN8	Uncharacterized protein.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.538
CMQ_1056	CMQ_161	F0XCF1	F0XR91	Uncharacterized protein.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.575
CMQ_1056	CMQ_1720	F0XCF1	F0XDV1	Uncharacterized protein.	Uncharacterized protein.	0.535
CMQ_1056	CMQ_4422	F0XCF1	F0XTR5	Uncharacterized protein.	Citrate synthase; Belongs to the citrate synthase family.	0.565
CMQ_1056	CMQ_4692	F0XCF1	F0XUN1	Uncharacterized protein.	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.649
CMQ_1056	CMQ_4999	F0XCF1	F0XKD0	Uncharacterized protein.	Citrate synthase; Belongs to the citrate synthase family.	0.565
CMQ_1056	CMQ_5074	F0XCF1	F0XKB7	Uncharacterized protein.	Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.603
CMQ_1056	CMQ_5251	F0XCF1	F0XBU6	Uncharacterized protein.	Uncharacterized protein.	0.603
CMQ_1056	CMQ_5252	F0XCF1	F0XBE2	Uncharacterized protein.	Uncharacterized protein.	0.603
CMQ_1056	CMQ_6014	F0XCF1	F0XLX0	Uncharacterized protein.	Alanine aminotransferase.	0.465
CMQ_1056	CMQ_6646	F0XCF1	F0X781	Uncharacterized protein.	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.	0.599
CMQ_1056	CMQ_6877	F0XCF1	F0X7T5	Uncharacterized protein.	Aspartate aminotransferase.	0.509
CMQ_1056	CMQ_6933	F0XCF1	F0X7X8	Uncharacterized protein.	Mitochondrial acetolactate synthase small.	0.777
CMQ_1056	CMQ_7089	F0XCF1	F0XNZ9	Uncharacterized protein.	Dihydroxy-acid dehydratase.	0.438
CMQ_1056	CMQ_8199	F0XCF1	F0XL52	Uncharacterized protein.	Acetolactate synthase.	0.634
CMQ_1056	CMQ_963	F0XCF1	F0XET3	Uncharacterized protein.	Dihydroxy-acid dehydratase.	0.438
CMQ_1163	CMQ_1214	F0XEE0	F0XFI9	Histidine acid phosphatase.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.835
CMQ_1163	CMQ_1367	F0XEE0	F0XDV0	Histidine acid phosphatase.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.690