STRINGSTRING
FEN1 FEN1 CMQ_3837 CMQ_3837 CMQ_3289 CMQ_3289 CMQ_3625 CMQ_3625 CMQ_2494 CMQ_2494 CMQ_3042 CMQ_3042 CMQ_805 CMQ_805 CMQ_4653 CMQ_4653 CMQ_7632 CMQ_7632 CMQ_7482 CMQ_7482 CMQ_6492 CMQ_6492
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (856 aa)
CMQ_3837Uncharacterized protein. (951 aa)
CMQ_3289Dsb repair complex subunit. (685 aa)
CMQ_3625Meiotic recombination protein mre11. (1249 aa)
CMQ_2494ATP dependent DNA ligase domain containing protein. (670 aa)
CMQ_3042DNA ligase. (1019 aa)
CMQ_805DNA polymerase. (274 aa)
CMQ_4653DNA repair protein rad50. (1301 aa)
CMQ_7632Sam domain containing protein. (1815 aa)
CMQ_7482Ku family DNA-binding protein. (734 aa)
CMQ_6492DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (686 aa)
Your Current Organism:
Grosmannia clavigera
NCBI taxonomy Id: 655863
Other names: G. clavigera kw1407, Grosmannia clavigera kw1407
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