node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEH08135.1 | AEH08317.1 | FsymDg_0609 | FsymDg_0803 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Fructose-1,6-bisphosphatase, class II; TIGRFAM: GlpX; KEGG: fal:FRAAL6145 fructose 1,6-bisphosphatase II; PFAM: GlpX. | 0.947 |
AEH08135.1 | AEH08594.1 | FsymDg_0609 | FsymDg_1093 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal; Sugar isomerase (SIS); KEGG: fal:FRAAL1273 hypothetical protein. | 0.939 |
AEH08135.1 | AEH09095.1 | FsymDg_0609 | FsymDg_1639 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 1-deoxy-D-xylulose-5-phosphate synthase; KEGG: fra:Francci3_1278 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. | 0.957 |
AEH08135.1 | AEH09147.1 | FsymDg_0609 | FsymDg_1697 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: fre:Franean1_2063 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.995 |
AEH08135.1 | AEH09202.1 | FsymDg_0609 | FsymDg_1753 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; manually curated; KEGG: fal:FRAAL4537 pyruvate kinase; TIGRFAM: Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.961 |
AEH08135.1 | AEH09819.1 | FsymDg_0609 | FsymDg_2441 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | TIGRFAM: Transketolase, bacterial-like; KEGG: afw:Anae109_2025 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; Belongs to the transketolase family. | 0.904 |
AEH08135.1 | AEH10605.1 | FsymDg_0609 | FsymDg_3301 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | TIGRFAM: Ribulose-phosphate 3-epimerase; KEGG: fra:Francci3_3188 ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.544 |
AEH08135.1 | AEH10905.1 | FsymDg_0609 | FsymDg_3626 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | HAMAP: phosphoketolase; KEGG: fre:Franean1_1196 putative phosphoketolase; PFAM: Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal; Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase; Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal. | 0.909 |
AEH08135.1 | eno | FsymDg_0609 | FsymDg_0755 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.986 |
AEH08135.1 | gpmA | FsymDg_0609 | FsymDg_4069 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.950 |
AEH08135.1 | pfkA | FsymDg_0609 | FsymDg_4192 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.972 |
AEH08135.1 | pfp | FsymDg_0609 | FsymDg_3146 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.976 |
AEH08135.1 | pgi | FsymDg_0609 | FsymDg_4480 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | HAMAP: Phosphoglucose isomerase (PGI); KEGG: fre:Franean1_7286 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family. | 0.970 |
AEH08135.1 | pgk | FsymDg_0609 | FsymDg_1698 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | HAMAP: Phosphoglycerate kinase; KEGG: fra:Francci3_1638 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.992 |
AEH08135.1 | tal | FsymDg_0609 | FsymDg_1707 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.975 |
AEH08135.1 | tpiA | FsymDg_0609 | FsymDg_1699 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.997 |
AEH08317.1 | AEH08135.1 | FsymDg_0803 | FsymDg_0609 | Fructose-1,6-bisphosphatase, class II; TIGRFAM: GlpX; KEGG: fal:FRAAL6145 fructose 1,6-bisphosphatase II; PFAM: GlpX. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.947 |
AEH08317.1 | AEH08594.1 | FsymDg_0803 | FsymDg_1093 | Fructose-1,6-bisphosphatase, class II; TIGRFAM: GlpX; KEGG: fal:FRAAL6145 fructose 1,6-bisphosphatase II; PFAM: GlpX. | PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal; Sugar isomerase (SIS); KEGG: fal:FRAAL1273 hypothetical protein. | 0.865 |
AEH08317.1 | AEH09095.1 | FsymDg_0803 | FsymDg_1639 | Fructose-1,6-bisphosphatase, class II; TIGRFAM: GlpX; KEGG: fal:FRAAL6145 fructose 1,6-bisphosphatase II; PFAM: GlpX. | 1-deoxy-D-xylulose-5-phosphate synthase; KEGG: fra:Francci3_1278 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. | 0.931 |
AEH08317.1 | AEH09147.1 | FsymDg_0803 | FsymDg_1697 | Fructose-1,6-bisphosphatase, class II; TIGRFAM: GlpX; KEGG: fal:FRAAL6145 fructose 1,6-bisphosphatase II; PFAM: GlpX. | TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: fre:Franean1_2063 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.834 |