STRINGSTRING
eno eno pgi pgi AEH11721.1 AEH11721.1 AEH11720.1 AEH11720.1 AEH11719.1 AEH11719.1 AEH11514.1 AEH11514.1 pfkA pfkA gpmA gpmA AEH11299.1 AEH11299.1 AEH11266.1 AEH11266.1 AEH11265.1 AEH11265.1 AEH11077.1 AEH11077.1 AEH10863.1 AEH10863.1 AEH10776.1 AEH10776.1 AEH10775.1 AEH10775.1 AEH10524.1 AEH10524.1 AEH10462.1 AEH10462.1 pfp pfp AEH10144.1 AEH10144.1 AEH10143.1 AEH10143.1 AEH09890.1 AEH09890.1 AEH09670.1 AEH09670.1 AEH09507.1 AEH09507.1 AEH09497.1 AEH09497.1 AEH09464.1 AEH09464.1 AEH09452.1 AEH09452.1 AEH09433.1 AEH09433.1 AEH09373.1 AEH09373.1 AEH09325.1 AEH09325.1 AEH09292.1 AEH09292.1 AEH09202.1 AEH09202.1 tpiA tpiA pgk pgk AEH09147.1 AEH09147.1 AEH09093.1 AEH09093.1 AEH09015.1 AEH09015.1 AEH09012.1 AEH09012.1 AEH08761.1 AEH08761.1 AEH08741.1 AEH08741.1 AEH08594.1 AEH08594.1 AEH08317.1 AEH08317.1 pckG pckG AEH08135.1 AEH08135.1 AEH08118.1 AEH08118.1 AEH08066.1 AEH08066.1 AEH07851.1 AEH07851.1 AEH07620.1 AEH07620.1 AEH07612.1 AEH07612.1 AEH07608.1 AEH07608.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
pgiHAMAP: Phosphoglucose isomerase (PGI); KEGG: fre:Franean1_7286 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family. (573 aa)
AEH11721.1Dihydrolipoyllysine-residue acetyltransferase; KEGG: fre:Franean1_7269 dehydrogenase catalytic domain-containing protein; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding. (534 aa)
AEH11720.1Pyruvate dehydrogenase (acetyl-transferring); KEGG: fre:Franean1_7268 transketolase central region; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. (364 aa)
AEH11719.13-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); KEGG: fri:FraEuI1c_7123 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase, E1 component. (518 aa)
AEH11514.1ROK family protein; PFAM: ROK; KEGG: fra:Francci3_0253 ROK. (421 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (488 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (245 aa)
AEH11299.1KEGG: fri:FraEuI1c_7079 DNA binding domain protein, excisionase family; TIGRFAM: Excisionase/Xis, DNA-binding; PFAM: HTH transcriptional regulator, MerR. (69 aa)
AEH11266.1KEGG: fal:FRAAL1050 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (353 aa)
AEH11265.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: fal:FRAAL1051 putative oxidoreductase,alpha subunit; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (627 aa)
AEH11077.1TIGRFAM: Acetate--CoA ligase; KEGG: fre:Franean1_1068 acetate--CoA ligase; PFAM: AMP-dependent synthetase/ligase. (673 aa)
AEH10863.1KEGG: fre:Franean1_1252 polyphosphate--glucose phosphotransferase; PFAM: ROK. (274 aa)
AEH10776.1PFAM: Aldehyde dehydrogenase; KEGG: nfa:nfa29950 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (505 aa)
AEH10775.1PFAM: Protein of unknown function DUF779; KEGG: mab:MAB_0973 hypothetical protein. (146 aa)
AEH10524.1TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: fal:FRAAL5151 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation. (460 aa)
AEH10462.1Glucokinase, ROK family; TIGRFAM: Glucokinase ROK; KEGG: fre:Franean1_1825 ROK family glucokinase; PFAM: ROK. (328 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (341 aa)
AEH10144.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: stp:Strop_0699 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal. (614 aa)
AEH10143.1KEGG: mil:ML5_0899 2-oxoglutarate synthase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding. (344 aa)
AEH09890.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (929 aa)
AEH09670.1Putative phosphomutase; KEGG: fri:FraEuI1c_3765 phosphoglycerate mutase; TIGRFAM: putative phosphomutase; PFAM: Phosphoglycerate mutase. (263 aa)
AEH09507.1Pyruvate, water dikinase; KEGG: mav:MAV_5056 PEP-utilizing protein; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding. (779 aa)
AEH09497.1KEGG: fal:FRAAL1665 acetaldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase. (503 aa)
AEH09464.1Butyrate--CoA ligase; KEGG: ami:Amir_2275 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase. (586 aa)
AEH09452.1KEGG: rop:ROP_45660 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (486 aa)
AEH09433.1KEGG: rop:ROP_45780 acetate--CoA ligase; PFAM: AMP-dependent synthetase/ligase. (667 aa)
AEH09373.1Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; KEGG: fre:Franean1_3484 dehydrogenase catalytic domain-containing protein. (310 aa)
AEH09325.1PFAM: Aldehyde dehydrogenase; KEGG: mjl:Mjls_0080 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (465 aa)
AEH09292.1PFAM: Phosphoglycerate mutase; KEGG: sro:Sros_9413 hypothetical protein. (264 aa)
AEH09202.1PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; manually curated; KEGG: fal:FRAAL4537 pyruvate kinase; TIGRFAM: Pyruvate kinase; Belongs to the pyruvate kinase family. (471 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (275 aa)
pgkHAMAP: Phosphoglycerate kinase; KEGG: fra:Francci3_1638 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (421 aa)
AEH09147.1TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: fre:Franean1_2063 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
AEH09093.1TIGRFAM: Pyruvate, phosphate dikinase; KEGG: ace:Acel_0801 pyruvate phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; PEP-utilising enzyme; Belongs to the PEP-utilizing enzyme family. (899 aa)
AEH09015.1PFAM: Phosphoglycerate mutase; KEGG: fre:Franean1_5245 phosphoglycerate mutase. (242 aa)
AEH09012.1TIGRFAM: Phosphoglucomutase, alpha-D-glucose specific; KEGG: fal:FRAAL1935 phosphoglucomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal. (554 aa)
AEH08761.1PFAM: Lytic transglycosylase-like, catalytic; KEGG: fri:FraEuI1c_5825 lytic transglycosylase catalytic. (217 aa)
AEH08741.1CopG-like domain-containing protein DNA-binding protein; PFAM: CopG-like DNA-binding; KEGG: mtb:TBMG_01995 antitoxin. (89 aa)
AEH08594.1PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal; Sugar isomerase (SIS); KEGG: fal:FRAAL1273 hypothetical protein. (399 aa)
AEH08317.1Fructose-1,6-bisphosphatase, class II; TIGRFAM: GlpX; KEGG: fal:FRAAL6145 fructose 1,6-bisphosphatase II; PFAM: GlpX. (341 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (607 aa)
AEH08135.1Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (345 aa)
AEH08118.1KEGG: fre:Franean1_6571 alcohol dehydrogenase zinc-binding type 2; TIGRFAM: Alcohol dehydrogenase, zinc-binding type 2; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, zinc-binding. (338 aa)
AEH08066.1KEGG: fri:FraEuI1c_2128 hypothetical protein. (596 aa)
AEH07851.1KEGG: fre:Franean1_7205 DNA binding domain-containing protein; TIGRFAM: Excisionase/Xis, DNA-binding; PFAM: HTH transcriptional regulator, MerR. (68 aa)
AEH07620.1Dihydrolipoyl dehydrogenase; KEGG: fra:Francci3_0937 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase, dimerisation; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (468 aa)
AEH07612.1KEGG: rer:RER_08030 pyruvate phosphate dikinase; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region. (497 aa)
AEH07608.1PFAM: PEP-utilising enzyme, mobile region; KEGG: mav:MAV_5056 PEP-utilizing protein. (580 aa)
Your Current Organism:
Frankia symbiont
NCBI taxonomy Id: 656024
Other names: F. symbiont of Datisca glomerata, Frankia symbiont of Datisca glomerata
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