(20 nodes) Glycosylphosphatidylinositol (GPI)-anchor biosynthesis network (Tuber melanosporum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G4P8_TUBMM	Uncharacterized protein. (432 aa)
	D5G6K8_TUBMM	Uncharacterized protein. (614 aa)
	D5G6L0_TUBMM	Uncharacterized protein. (244 aa)
	D5G6P6_TUBMM	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (1079 aa)
	D5G8Q0_TUBMM	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity. (422 aa)
	D5G8R9_TUBMM	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (398 aa)
	D5G965_TUBMM	PIG-P domain-containing protein. (349 aa)
	D5GB35_TUBMM	Uncharacterized protein. (223 aa)
	D5GDE0_TUBMM	Uncharacterized protein. (852 aa)
	D5GH33_TUBMM	Uncharacterized protein. (238 aa)
	D5GHT2_TUBMM	Uncharacterized protein. (417 aa)
	D5GJL4_TUBMM	Uncharacterized protein. (972 aa)
	D5GJW1_TUBMM	Uncharacterized protein. (556 aa)
	D5GLN6_TUBMM	Uncharacterized protein. (739 aa)
	D5GLW5_TUBMM	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (83 aa)
	D5GMD7_TUBMM	Uncharacterized protein. (1088 aa)
	D5GMF8_TUBMM	Uncharacterized protein. (573 aa)
	D5GND6_TUBMM	Mannosyltransferase. (568 aa)
	D5GNK1_TUBMM	Uncharacterized protein. (458 aa)
	D5GQ47_TUBMM	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (375 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G4P8_TUBMM	D5G6K8_TUBMM	D5G4P8	D5G6K8	Uncharacterized protein.	Uncharacterized protein.	0.558
D5G4P8_TUBMM	D5G6L0_TUBMM	D5G4P8	D5G6L0	Uncharacterized protein.	Uncharacterized protein.	0.989
D5G4P8_TUBMM	D5G6P6_TUBMM	D5G4P8	D5G6P6	Uncharacterized protein.	GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.	0.479
D5G4P8_TUBMM	D5G8Q0_TUBMM	D5G4P8	D5G8Q0	Uncharacterized protein.	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity.	0.437
D5G4P8_TUBMM	D5G8R9_TUBMM	D5G4P8	D5G8R9	Uncharacterized protein.	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.	0.629
D5G4P8_TUBMM	D5G965_TUBMM	D5G4P8	D5G965	Uncharacterized protein.	PIG-P domain-containing protein.	0.987
D5G4P8_TUBMM	D5GDE0_TUBMM	D5G4P8	D5GDE0	Uncharacterized protein.	Uncharacterized protein.	0.617
D5G4P8_TUBMM	D5GH33_TUBMM	D5G4P8	D5GH33	Uncharacterized protein.	Uncharacterized protein.	0.965
D5G4P8_TUBMM	D5GHT2_TUBMM	D5G4P8	D5GHT2	Uncharacterized protein.	Uncharacterized protein.	0.523
D5G4P8_TUBMM	D5GJL4_TUBMM	D5G4P8	D5GJL4	Uncharacterized protein.	Uncharacterized protein.	0.616
D5G4P8_TUBMM	D5GJW1_TUBMM	D5G4P8	D5GJW1	Uncharacterized protein.	Uncharacterized protein.	0.623
D5G4P8_TUBMM	D5GLN6_TUBMM	D5G4P8	D5GLN6	Uncharacterized protein.	Uncharacterized protein.	0.989
D5G4P8_TUBMM	D5GLW5_TUBMM	D5G4P8	D5GLW5	Uncharacterized protein.	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.	0.989
D5G4P8_TUBMM	D5GMD7_TUBMM	D5G4P8	D5GMD7	Uncharacterized protein.	Uncharacterized protein.	0.617
D5G4P8_TUBMM	D5GMF8_TUBMM	D5G4P8	D5GMF8	Uncharacterized protein.	Uncharacterized protein.	0.471
D5G4P8_TUBMM	D5GND6_TUBMM	D5G4P8	D5GND6	Uncharacterized protein.	Mannosyltransferase.	0.618
D5G4P8_TUBMM	D5GNK1_TUBMM	D5G4P8	D5GNK1	Uncharacterized protein.	Uncharacterized protein.	0.992
D5G4P8_TUBMM	D5GQ47_TUBMM	D5G4P8	D5GQ47	Uncharacterized protein.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.624
D5G6K8_TUBMM	D5G4P8_TUBMM	D5G6K8	D5G4P8	Uncharacterized protein.	Uncharacterized protein.	0.558
D5G6K8_TUBMM	D5G6L0_TUBMM	D5G6K8	D5G6L0	Uncharacterized protein.	Uncharacterized protein.	0.588