(110 nodes) Mixed, incl. MAPK signaling pathway - yeast, and GPCR downstream signalling network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G3W1_TUBMM	PH domain-containing protein. (702 aa)
	D5G423_TUBMM	Uncharacterized protein. (192 aa)
	D5G4A7_TUBMM	Rho-GAP domain-containing protein. (764 aa)
	D5G4A8_TUBMM	Uncharacterized protein. (1180 aa)
	D5G4B3_TUBMM	MHYT domain-containing protein. (784 aa)
	D5G4B9_TUBMM	RGS domain-containing protein. (376 aa)
	D5G4H0_TUBMM	Uncharacterized protein. (1580 aa)
	D5G4L4_TUBMM	Uncharacterized protein. (346 aa)
	D5G4P6_TUBMM	Response regulatory domain-containing protein. (512 aa)
	D5G4S1_TUBMM	Uncharacterized protein. (203 aa)
	D5G4S8_TUBMM	Uncharacterized protein. (1216 aa)
	D5G4S9_TUBMM	Uncharacterized protein; Belongs to the protein kinase superfamily. (430 aa)
	D5G4T5_TUBMM	Uncharacterized protein. (346 aa)
	D5G4Z0_TUBMM	Uncharacterized protein; Belongs to the DOCK family. (1876 aa)
	D5G5J5_TUBMM	Uncharacterized protein. (202 aa)
	D5G5K1_TUBMM	Uncharacterized protein. (382 aa)
	D5G5V5_TUBMM	Uncharacterized protein. (905 aa)
	D5G5X7_TUBMM	Uncharacterized protein. (1184 aa)
	D5G5Y2_TUBMM	Uncharacterized protein. (331 aa)
	D5G5Z4_TUBMM	Uncharacterized protein. (345 aa)
	D5G6H0_TUBMM	Uncharacterized protein. (203 aa)
	D5G6H3_TUBMM	Uncharacterized protein. (853 aa)
	D5G6T9_TUBMM	Uncharacterized protein. (997 aa)
	D5G6U0_TUBMM	Uncharacterized protein. (1042 aa)
	D5G6V5_TUBMM	Uncharacterized protein. (224 aa)
	D5G6X6_TUBMM	MAP kinase kinase kinase. (1356 aa)
	D5G7A3_TUBMM	Uncharacterized protein. (450 aa)
	D5G7X3_TUBMM	Uncharacterized protein. (129 aa)
	D5G806_TUBMM	Zn_dep_PLPC domain-containing protein. (855 aa)
	D5G808_TUBMM	GPI-anchored wall transfer protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (481 aa)
	D5G8L8_TUBMM	Uncharacterized protein. (272 aa)
	D5G8L9_TUBMM	Protein kinase domain-containing protein. (346 aa)
	D5G8M4_TUBMM	Uncharacterized protein. (684 aa)
	D5G8P4_TUBMM	Uncharacterized protein. (196 aa)
	D5G8P5_TUBMM	Uncharacterized protein. (636 aa)
	D5G8T8_TUBMM	SH3 domain-containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (318 aa)
	D5G8U9_TUBMM	GGACT domain-containing protein. (206 aa)
	D5G9F9_TUBMM	Uncharacterized protein. (259 aa)
	D5G9M8_TUBMM	Uncharacterized protein. (168 aa)
	D5G9U8_TUBMM	Uncharacterized protein. (886 aa)
	D5GAB6_TUBMM	Uncharacterized protein. (563 aa)
	D5GAF3_TUBMM	Uncharacterized protein. (881 aa)
	D5GAM0_TUBMM	SH3 domain-containing protein. (256 aa)
	D5GB31_TUBMM	Rho-GAP domain-containing protein. (849 aa)
	D5GBF4_TUBMM	Uncharacterized protein; Belongs to the protein kinase superfamily. (356 aa)
	D5GBH8_TUBMM	Uncharacterized protein. (113 aa)
	D5GBK8_TUBMM	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (438 aa)
	D5GC39_TUBMM	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (351 aa)
	D5GC60_TUBMM	Uncharacterized protein. (199 aa)
	D5GCE4_TUBMM	Uncharacterized protein. (352 aa)
	D5GCE5_TUBMM	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (332 aa)
	D5GCF1_TUBMM	Uncharacterized protein. (1181 aa)
	D5GCN1_TUBMM	Uncharacterized protein; Belongs to the cytochrome P450 family. (397 aa)
	D5GDI4_TUBMM	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (427 aa)
	D5GDL3_TUBMM	Uncharacterized protein. (857 aa)
	D5GDX4_TUBMM	Protein kinase domain-containing protein. (1927 aa)
	D5GEH9_TUBMM	Uncharacterized protein. (626 aa)
	D5GEJ0_TUBMM	Uncharacterized protein. (206 aa)
	D5GEL4_TUBMM	Uncharacterized protein. (345 aa)
	D5GEL5_TUBMM	Protein kinase domain-containing protein. (288 aa)
	D5GET4_TUBMM	Uncharacterized protein. (211 aa)
	D5GF01_TUBMM	Uncharacterized protein. (1595 aa)
	D5GF18_TUBMM	Ras-GAP domain-containing protein. (2351 aa)
	D5GFA8_TUBMM	Uncharacterized protein. (903 aa)
	D5GFB2_TUBMM	Uncharacterized protein. (2015 aa)
	D5GFE8_TUBMM	Uncharacterized protein. (961 aa)
	D5GFL1_TUBMM	Non-specific serine/threonine protein kinase. (848 aa)
	D5GG06_TUBMM	Uncharacterized protein. (1066 aa)
	D5GG12_TUBMM	Zn(2)-C6 fungal-type domain-containing protein. (778 aa)
	D5GGD7_TUBMM	Uncharacterized protein. (973 aa)
	D5GGF7_TUBMM	cAMP-dependent protein kinase regulatory subunit. (514 aa)
	D5GGL3_TUBMM	Uncharacterized protein. (232 aa)
	D5GGR0_TUBMM	Ras-GAP domain-containing protein. (782 aa)
	D5GGR6_TUBMM	Uncharacterized protein; Belongs to the glycosyl hydrolase 17 family. (305 aa)
	D5GGT5_TUBMM	Uncharacterized protein. (373 aa)
	D5GH10_TUBMM	Uncharacterized protein. (398 aa)
	D5GHC4_TUBMM	Uncharacterized protein. (1063 aa)
	D5GI23_TUBMM	Uncharacterized protein. (967 aa)
	D5GIT2_TUBMM	Uncharacterized protein. (1088 aa)
	D5GIT4_TUBMM	HPt domain-containing protein. (171 aa)
	D5GIU3_TUBMM	G_PROTEIN_RECEP_F2_4 domain-containing protein. (590 aa)
	D5GIW3_TUBMM	DUF1708 domain-containing protein. (1018 aa)
	D5GIW5_TUBMM	MADS-box domain-containing protein. (563 aa)
	D5GJH4_TUBMM	Protein kinase domain-containing protein. (510 aa)
	D5GJH6_TUBMM	Protein kinase domain-containing protein. (510 aa)
	D5GJR3_TUBMM	Uncharacterized protein. (611 aa)
	D5GJX8_TUBMM	Uncharacterized protein. (714 aa)
	D5GK80_TUBMM	Uncharacterized protein. (294 aa)
	D5GKW4_TUBMM	Uncharacterized protein. (1164 aa)
	D5GKW7_TUBMM	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (233 aa)
	D5GKY2_TUBMM	Phosphodiesterase. (794 aa)
	D5GL49_TUBMM	Uncharacterized protein. (596 aa)
	D5GLA9_TUBMM	WD_REPEATS_REGION domain-containing protein. (347 aa)
	D5GLD1_TUBMM	PPM-type phosphatase domain-containing protein. (447 aa)
	D5GLF6_TUBMM	Uncharacterized protein. (439 aa)
	D5GLY0_TUBMM	Uncharacterized protein. (890 aa)
	D5GMC6_TUBMM	ELMO domain-containing protein. (686 aa)
	D5GMN9_TUBMM	Uncharacterized protein. (508 aa)
	D5GMT2_TUBMM	Uncharacterized protein. (221 aa)
	D5GMZ2_TUBMM	DH domain-containing protein. (1900 aa)
	D5GN31_TUBMM	Uncharacterized protein. (353 aa)
	D5GN39_TUBMM	Uncharacterized protein. (261 aa)
	D5GN61_TUBMM	Uncharacterized protein. (351 aa)
	D5GN73_TUBMM	Uncharacterized protein. (390 aa)
	D5GPI8_TUBMM	Protein kinase domain-containing protein. (573 aa)
	D5GPP3_TUBMM	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (263 aa)
	D5GPS4_TUBMM	Ras-GAP domain-containing protein. (1224 aa)
	D5GPY6_TUBMM	G protein gamma domain-containing protein. (88 aa)
	D5GQ09_TUBMM	NodB homology domain-containing protein. (197 aa)
	D5GQ49_TUBMM	MADS-box domain-containing protein. (248 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G3W1_TUBMM	D5G4A8_TUBMM	D5G3W1	D5G4A8	PH domain-containing protein.	Uncharacterized protein.	0.583
D5G3W1_TUBMM	D5G4S1_TUBMM	D5G3W1	D5G4S1	PH domain-containing protein.	Uncharacterized protein.	0.651
D5G3W1_TUBMM	D5G5K1_TUBMM	D5G3W1	D5G5K1	PH domain-containing protein.	Uncharacterized protein.	0.651
D5G3W1_TUBMM	D5G5Y2_TUBMM	D5G3W1	D5G5Y2	PH domain-containing protein.	Uncharacterized protein.	0.632
D5G3W1_TUBMM	D5G6H3_TUBMM	D5G3W1	D5G6H3	PH domain-containing protein.	Uncharacterized protein.	0.589
D5G3W1_TUBMM	D5G6V5_TUBMM	D5G3W1	D5G6V5	PH domain-containing protein.	Uncharacterized protein.	0.651
D5G3W1_TUBMM	D5G806_TUBMM	D5G3W1	D5G806	PH domain-containing protein.	Zn_dep_PLPC domain-containing protein.	0.566
D5G3W1_TUBMM	D5G8L8_TUBMM	D5G3W1	D5G8L8	PH domain-containing protein.	Uncharacterized protein.	0.436
D5G3W1_TUBMM	D5G8L9_TUBMM	D5G3W1	D5G8L9	PH domain-containing protein.	Protein kinase domain-containing protein.	0.436
D5G3W1_TUBMM	D5GAM0_TUBMM	D5G3W1	D5GAM0	PH domain-containing protein.	SH3 domain-containing protein.	0.737
D5G3W1_TUBMM	D5GBK8_TUBMM	D5G3W1	D5GBK8	PH domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.436
D5G3W1_TUBMM	D5GEJ0_TUBMM	D5G3W1	D5GEJ0	PH domain-containing protein.	Uncharacterized protein.	0.589
D5G3W1_TUBMM	D5GGT5_TUBMM	D5G3W1	D5GGT5	PH domain-containing protein.	Uncharacterized protein.	0.589
D5G3W1_TUBMM	D5GHC4_TUBMM	D5G3W1	D5GHC4	PH domain-containing protein.	Uncharacterized protein.	0.583
D5G3W1_TUBMM	D5GKW7_TUBMM	D5G3W1	D5GKW7	PH domain-containing protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.615
D5G3W1_TUBMM	D5GPI8_TUBMM	D5G3W1	D5GPI8	PH domain-containing protein.	Protein kinase domain-containing protein.	0.436
D5G3W1_TUBMM	D5GPP3_TUBMM	D5G3W1	D5GPP3	PH domain-containing protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.615
D5G423_TUBMM	D5G4A7_TUBMM	D5G423	D5G4A7	Uncharacterized protein.	Rho-GAP domain-containing protein.	0.591
D5G423_TUBMM	D5G4A8_TUBMM	D5G423	D5G4A8	Uncharacterized protein.	Uncharacterized protein.	0.477
D5G423_TUBMM	D5G4H0_TUBMM	D5G423	D5G4H0	Uncharacterized protein.	Uncharacterized protein.	0.619