(47 nodes) Mixed, incl. RHOD GTPase cycle, and Small GTPase mediated signal transduction network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G423_TUBMM	Uncharacterized protein. (192 aa)
	D5G4A7_TUBMM	Rho-GAP domain-containing protein. (764 aa)
	D5G4A8_TUBMM	Uncharacterized protein. (1180 aa)
	D5G4H0_TUBMM	Uncharacterized protein. (1580 aa)
	D5G4S1_TUBMM	Uncharacterized protein. (203 aa)
	D5G4S8_TUBMM	Uncharacterized protein. (1216 aa)
	D5G4S9_TUBMM	Uncharacterized protein; Belongs to the protein kinase superfamily. (430 aa)
	D5G4T5_TUBMM	Uncharacterized protein. (346 aa)
	D5G4Z0_TUBMM	Uncharacterized protein; Belongs to the DOCK family. (1876 aa)
	D5G5J5_TUBMM	Uncharacterized protein. (202 aa)
	D5G5K1_TUBMM	Uncharacterized protein. (382 aa)
	D5G5V5_TUBMM	Uncharacterized protein. (905 aa)
	D5G5X7_TUBMM	Uncharacterized protein. (1184 aa)
	D5G6H0_TUBMM	Uncharacterized protein. (203 aa)
	D5G6T9_TUBMM	Uncharacterized protein. (997 aa)
	D5G6U0_TUBMM	Uncharacterized protein. (1042 aa)
	D5G6V5_TUBMM	Uncharacterized protein. (224 aa)
	D5G8M4_TUBMM	Uncharacterized protein. (684 aa)
	D5G8P4_TUBMM	Uncharacterized protein. (196 aa)
	D5G8P5_TUBMM	Uncharacterized protein. (636 aa)
	D5G9U8_TUBMM	Uncharacterized protein. (886 aa)
	D5GB31_TUBMM	Rho-GAP domain-containing protein. (849 aa)
	D5GBF4_TUBMM	Uncharacterized protein; Belongs to the protein kinase superfamily. (356 aa)
	D5GC60_TUBMM	Uncharacterized protein. (199 aa)
	D5GCF1_TUBMM	Uncharacterized protein. (1181 aa)
	D5GEL4_TUBMM	Uncharacterized protein. (345 aa)
	D5GEL5_TUBMM	Protein kinase domain-containing protein. (288 aa)
	D5GET4_TUBMM	Uncharacterized protein. (211 aa)
	D5GF18_TUBMM	Ras-GAP domain-containing protein. (2351 aa)
	D5GFB2_TUBMM	Uncharacterized protein. (2015 aa)
	D5GFL1_TUBMM	Non-specific serine/threonine protein kinase. (848 aa)
	D5GGD7_TUBMM	Uncharacterized protein. (973 aa)
	D5GGF7_TUBMM	cAMP-dependent protein kinase regulatory subunit. (514 aa)
	D5GGL3_TUBMM	Uncharacterized protein. (232 aa)
	D5GGR0_TUBMM	Ras-GAP domain-containing protein. (782 aa)
	D5GH10_TUBMM	Uncharacterized protein. (398 aa)
	D5GHC4_TUBMM	Uncharacterized protein. (1063 aa)
	D5GIT2_TUBMM	Uncharacterized protein. (1088 aa)
	D5GIW3_TUBMM	DUF1708 domain-containing protein. (1018 aa)
	D5GJR3_TUBMM	Uncharacterized protein. (611 aa)
	D5GJX8_TUBMM	Uncharacterized protein. (714 aa)
	D5GKY2_TUBMM	Phosphodiesterase. (794 aa)
	D5GMC6_TUBMM	ELMO domain-containing protein. (686 aa)
	D5GMT2_TUBMM	Uncharacterized protein. (221 aa)
	D5GMZ2_TUBMM	DH domain-containing protein. (1900 aa)
	D5GPS4_TUBMM	Ras-GAP domain-containing protein. (1224 aa)
	D5GPY6_TUBMM	G protein gamma domain-containing protein. (88 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G423_TUBMM	D5G4A7_TUBMM	D5G423	D5G4A7	Uncharacterized protein.	Rho-GAP domain-containing protein.	0.591
D5G423_TUBMM	D5G4A8_TUBMM	D5G423	D5G4A8	Uncharacterized protein.	Uncharacterized protein.	0.477
D5G423_TUBMM	D5G4H0_TUBMM	D5G423	D5G4H0	Uncharacterized protein.	Uncharacterized protein.	0.619
D5G423_TUBMM	D5G4S1_TUBMM	D5G423	D5G4S1	Uncharacterized protein.	Uncharacterized protein.	0.409
D5G423_TUBMM	D5G4S8_TUBMM	D5G423	D5G4S8	Uncharacterized protein.	Uncharacterized protein.	0.988
D5G423_TUBMM	D5G4T5_TUBMM	D5G423	D5G4T5	Uncharacterized protein.	Uncharacterized protein.	0.550
D5G423_TUBMM	D5G4Z0_TUBMM	D5G423	D5G4Z0	Uncharacterized protein.	Uncharacterized protein; Belongs to the DOCK family.	0.697
D5G423_TUBMM	D5G5J5_TUBMM	D5G423	D5G5J5	Uncharacterized protein.	Uncharacterized protein.	0.923
D5G423_TUBMM	D5G5K1_TUBMM	D5G423	D5G5K1	Uncharacterized protein.	Uncharacterized protein.	0.411
D5G423_TUBMM	D5G5X7_TUBMM	D5G423	D5G5X7	Uncharacterized protein.	Uncharacterized protein.	0.987
D5G423_TUBMM	D5G6U0_TUBMM	D5G423	D5G6U0	Uncharacterized protein.	Uncharacterized protein.	0.963
D5G423_TUBMM	D5G8P4_TUBMM	D5G423	D5G8P4	Uncharacterized protein.	Uncharacterized protein.	0.619
D5G423_TUBMM	D5G8P5_TUBMM	D5G423	D5G8P5	Uncharacterized protein.	Uncharacterized protein.	0.590
D5G423_TUBMM	D5GB31_TUBMM	D5G423	D5GB31	Uncharacterized protein.	Rho-GAP domain-containing protein.	0.980
D5G423_TUBMM	D5GCF1_TUBMM	D5G423	D5GCF1	Uncharacterized protein.	Uncharacterized protein.	0.999
D5G423_TUBMM	D5GEL4_TUBMM	D5G423	D5GEL4	Uncharacterized protein.	Uncharacterized protein.	0.576
D5G423_TUBMM	D5GEL5_TUBMM	D5G423	D5GEL5	Uncharacterized protein.	Protein kinase domain-containing protein.	0.577
D5G423_TUBMM	D5GET4_TUBMM	D5G423	D5GET4	Uncharacterized protein.	Uncharacterized protein.	0.901
D5G423_TUBMM	D5GFL1_TUBMM	D5G423	D5GFL1	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.577
D5G423_TUBMM	D5GGD7_TUBMM	D5G423	D5GGD7	Uncharacterized protein.	Uncharacterized protein.	0.711