(95 nodes) Cross-presentation of soluble exogenous antigens (endosomes), and Neddylation network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G413_TUBMM	AAA domain-containing protein; Belongs to the AAA ATPase family. (386 aa)
	D5G4D4_TUBMM	GCR1_C domain-containing protein. (509 aa)
	D5G4M1_TUBMM	AAA domain-containing protein; Belongs to the AAA ATPase family. (389 aa)
	D5G538_TUBMM	Proteasome subunit beta. (282 aa)
	D5G541_TUBMM	UCH_1 domain-containing protein. (425 aa)
	D5G5C4_TUBMM	AAA domain-containing protein; Belongs to the AAA ATPase family. (267 aa)
	D5G5C5_TUBMM	Uncharacterized protein. (175 aa)
	D5G5J8_TUBMM	CPSF_A domain-containing protein. (1053 aa)
	D5G5T3_TUBMM	Uncharacterized protein. (43 aa)
	D5G614_TUBMM	Ubiquitin-like domain-containing protein. (77 aa)
	D5G6A0_TUBMM	Nas2_N domain-containing protein. (231 aa)
	D5G6B0_TUBMM	Uncharacterized protein. (454 aa)
	D5G6M0_TUBMM	CULLIN_2 domain-containing protein; Belongs to the cullin family. (768 aa)
	D5G6Q0_TUBMM	Proteasome subunit alpha type. (285 aa)
	D5G6S4_TUBMM	F-box domain-containing protein. (568 aa)
	D5G6T7_TUBMM	Uncharacterized protein. (622 aa)
	D5G787_TUBMM	Uncharacterized protein. (406 aa)
	D5G7A7_TUBMM	RING-type domain-containing protein. (112 aa)
	D5G866_TUBMM	Uncharacterized protein. (229 aa)
	D5G883_TUBMM	Uncharacterized protein. (257 aa)
	D5G8F9_TUBMM	MPN domain-containing protein. (331 aa)
	D5G8L0_TUBMM	Ubiquitin carboxyl-terminal hydrolase. (313 aa)
	D5G8W7_TUBMM	MPN domain-containing protein. (383 aa)
	D5G956_TUBMM	26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (902 aa)
	D5G9A2_TUBMM	Uncharacterized protein. (311 aa)
	D5G9G0_TUBMM	F-box domain-containing protein. (605 aa)
	D5G9G3_TUBMM	26S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. (952 aa)
	D5G9X1_TUBMM	Ubiquitin-like domain-containing protein. (77 aa)
	D5GAV2_TUBMM	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (551 aa)
	D5GAY8_TUBMM	PCI domain-containing protein. (455 aa)
	D5GB69_TUBMM	PCI domain-containing protein. (261 aa)
	D5GB87_TUBMM	WD_REPEATS_REGION domain-containing protein. (443 aa)
	D5GBB1_TUBMM	Uncharacterized protein. (717 aa)
	D5GBB6_TUBMM	Proteasome subunit alpha type. (245 aa)
	D5GBD2_TUBMM	PCI domain-containing protein. (424 aa)
	D5GBD3_TUBMM	Uncharacterized protein. (269 aa)
	D5GBE1_TUBMM	VWFA domain-containing protein. (298 aa)
	D5GBG2_TUBMM	Proteasome subunit beta; Belongs to the peptidase T1B family. (260 aa)
	D5GBL0_TUBMM	Uncharacterized protein. (530 aa)
	D5GBQ3_TUBMM	Uncharacterized protein. (479 aa)
	D5GBZ1_TUBMM	MPN domain-containing protein. (345 aa)
	D5GCA7_TUBMM	Uncharacterized protein. (1841 aa)
	D5GCP3_TUBMM	Uncharacterized protein. (60 aa)
	D5GDH2_TUBMM	RPN13_C domain-containing protein. (317 aa)
	D5GDM8_TUBMM	Uncharacterized protein. (1022 aa)
	D5GEE0_TUBMM	Uncharacterized protein; Belongs to the SKP1 family. (160 aa)
	D5GF98_TUBMM	CULLIN_2 domain-containing protein; Belongs to the cullin family. (757 aa)
	D5GFF4_TUBMM	F-box domain-containing protein. (517 aa)
	D5GFF7_TUBMM	Uncharacterized protein. (315 aa)
	D5GFM4_TUBMM	Proteasome subunit alpha type. (249 aa)
	D5GGP4_TUBMM	PCI domain-containing protein. (382 aa)
	D5GH07_TUBMM	Uncharacterized protein. (569 aa)
	D5GH09_TUBMM	WD_REPEATS_REGION domain-containing protein. (395 aa)
	D5GHC7_TUBMM	PCI domain-containing protein. (414 aa)
	D5GHM8_TUBMM	CULLIN_2 domain-containing protein; Belongs to the cullin family. (873 aa)
	D5GHR2_TUBMM	Pr_beta_C domain-containing protein. (278 aa)
	D5GHS3_TUBMM	Proteasome subunit beta. (175 aa)
	D5GI20_TUBMM	AAA domain-containing protein; Belongs to the AAA ATPase family. (413 aa)
	D5GI31_TUBMM	WD_REPEATS_REGION domain-containing protein. (593 aa)
	D5GI44_TUBMM	F-box domain-containing protein. (501 aa)
	D5GI46_TUBMM	PCI domain-containing protein. (417 aa)
	D5GJ17_TUBMM	Proteasome subunit alpha type. (256 aa)
	D5GJ59_TUBMM	Uncharacterized protein. (204 aa)
	D5GK23_TUBMM	Uncharacterized protein. (358 aa)
	D5GK50_TUBMM	MPN domain-containing protein. (346 aa)
	D5GKM9_TUBMM	F-box domain-containing protein. (1153 aa)
	D5GKS5_TUBMM	PCI domain-containing protein. (323 aa)
	D5GKU5_TUBMM	AAA domain-containing protein; Belongs to the AAA ATPase family. (270 aa)
	D5GKU6_TUBMM	Uncharacterized protein. (129 aa)
	D5GL01_TUBMM	PCI domain-containing protein. (498 aa)
	D5GL27_TUBMM	Proteasome subunit alpha type. (247 aa)
	D5GL48_TUBMM	Ubiquitin carboxyl-terminal hydrolase. (263 aa)
	D5GLD2_TUBMM	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (367 aa)
	D5GLS8_TUBMM	PDZ_1 domain-containing protein. (995 aa)
	D5GLT6_TUBMM	Proteasome subunit alpha type. (259 aa)
	D5GM05_TUBMM	Uncharacterized protein. (461 aa)
	D5GM39_TUBMM	PCI domain-containing protein. (579 aa)
	D5GM49_TUBMM	PCI domain-containing protein. (399 aa)
	D5GMF9_TUBMM	E2_bind domain-containing protein. (410 aa)
	D5GMQ3_TUBMM	Uncharacterized protein. (365 aa)
	D5GMQ6_TUBMM	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (106 aa)
	D5GMY3_TUBMM	ULP_PROTEASE domain-containing protein. (308 aa)
	D5GMY8_TUBMM	AAA domain-containing protein; Belongs to the AAA ATPase family. (455 aa)
	D5GN88_TUBMM	CSN8_PSD8_EIF3K domain-containing protein. (217 aa)
	D5GNC8_TUBMM	Uncharacterized protein. (595 aa)
	D5GNL3_TUBMM	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (348 aa)
	D5GNQ8_TUBMM	DUF862 domain-containing protein. (259 aa)
	D5GNV9_TUBMM	Uncharacterized protein. (1840 aa)
	D5GNW9_TUBMM	Uncharacterized protein. (306 aa)
	D5GP36_TUBMM	TIP120 domain-containing protein. (1222 aa)
	D5GP51_TUBMM	Proteasome subunit beta; Belongs to the peptidase T1B family. (257 aa)
	D5GPG6_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (182 aa)
	D5GPN5_TUBMM	Uncharacterized protein. (593 aa)
	D5GPU3_TUBMM	Uncharacterized protein. (1077 aa)
	D5GQ08_TUBMM	Uncharacterized protein. (874 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G413_TUBMM	D5G4M1_TUBMM	D5G413	D5G4M1	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
D5G413_TUBMM	D5G538_TUBMM	D5G413	D5G538	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit beta.	0.998
D5G413_TUBMM	D5G541_TUBMM	D5G413	D5G541	AAA domain-containing protein; Belongs to the AAA ATPase family.	UCH_1 domain-containing protein.	0.905
D5G413_TUBMM	D5G5C4_TUBMM	D5G413	D5G5C4	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.990
D5G413_TUBMM	D5G5C5_TUBMM	D5G413	D5G5C5	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.985
D5G413_TUBMM	D5G614_TUBMM	D5G413	D5G614	AAA domain-containing protein; Belongs to the AAA ATPase family.	Ubiquitin-like domain-containing protein.	0.700
D5G413_TUBMM	D5G6A0_TUBMM	D5G413	D5G6A0	AAA domain-containing protein; Belongs to the AAA ATPase family.	Nas2_N domain-containing protein.	0.998
D5G413_TUBMM	D5G6B0_TUBMM	D5G413	D5G6B0	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.687
D5G413_TUBMM	D5G6M0_TUBMM	D5G413	D5G6M0	AAA domain-containing protein; Belongs to the AAA ATPase family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.633
D5G413_TUBMM	D5G6Q0_TUBMM	D5G413	D5G6Q0	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit alpha type.	0.999
D5G413_TUBMM	D5G7A7_TUBMM	D5G413	D5G7A7	AAA domain-containing protein; Belongs to the AAA ATPase family.	RING-type domain-containing protein.	0.622
D5G413_TUBMM	D5G866_TUBMM	D5G413	D5G866	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.998
D5G413_TUBMM	D5G883_TUBMM	D5G413	D5G883	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.998
D5G413_TUBMM	D5G8F9_TUBMM	D5G413	D5G8F9	AAA domain-containing protein; Belongs to the AAA ATPase family.	MPN domain-containing protein.	0.997
D5G413_TUBMM	D5G8L0_TUBMM	D5G413	D5G8L0	AAA domain-containing protein; Belongs to the AAA ATPase family.	Ubiquitin carboxyl-terminal hydrolase.	0.943
D5G413_TUBMM	D5G8W7_TUBMM	D5G413	D5G8W7	AAA domain-containing protein; Belongs to the AAA ATPase family.	MPN domain-containing protein.	0.626
D5G413_TUBMM	D5G956_TUBMM	D5G413	D5G956	AAA domain-containing protein; Belongs to the AAA ATPase family.	26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.999
D5G413_TUBMM	D5G9A2_TUBMM	D5G413	D5G9A2	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.969
D5G413_TUBMM	D5G9G3_TUBMM	D5G413	D5G9G3	AAA domain-containing protein; Belongs to the AAA ATPase family.	26S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.	0.999
D5G413_TUBMM	D5G9X1_TUBMM	D5G413	D5G9X1	AAA domain-containing protein; Belongs to the AAA ATPase family.	Ubiquitin-like domain-containing protein.	0.700