STRINGSTRING
D5G3X4_TUBMM D5G3X4_TUBMM D5G437_TUBMM D5G437_TUBMM D5G445_TUBMM D5G445_TUBMM MED18 MED18 MED5 MED5 D5G4U3_TUBMM D5G4U3_TUBMM D5G578_TUBMM D5G578_TUBMM D5G5S2_TUBMM D5G5S2_TUBMM D5G5S6_TUBMM D5G5S6_TUBMM D5G5X0_TUBMM D5G5X0_TUBMM D5G5X6_TUBMM D5G5X6_TUBMM D5G674_TUBMM D5G674_TUBMM D5G675_TUBMM D5G675_TUBMM MED17 MED17 D5G763_TUBMM D5G763_TUBMM D5G7D7_TUBMM D5G7D7_TUBMM D5G7D8_TUBMM D5G7D8_TUBMM D5G7P9_TUBMM D5G7P9_TUBMM D5G7Q2_TUBMM D5G7Q2_TUBMM D5G7T0_TUBMM D5G7T0_TUBMM D5G7W3_TUBMM D5G7W3_TUBMM D5G7W7_TUBMM D5G7W7_TUBMM D5G821_TUBMM D5G821_TUBMM D5G825_TUBMM D5G825_TUBMM D5G879_TUBMM D5G879_TUBMM D5G8A7_TUBMM D5G8A7_TUBMM D5G8D7_TUBMM D5G8D7_TUBMM D5G8D8_TUBMM D5G8D8_TUBMM D5G8G1_TUBMM D5G8G1_TUBMM D5G8S6_TUBMM D5G8S6_TUBMM D5G8Y9_TUBMM D5G8Y9_TUBMM D5G8Z9_TUBMM D5G8Z9_TUBMM D5G915_TUBMM D5G915_TUBMM D5G963_TUBMM D5G963_TUBMM D5G997_TUBMM D5G997_TUBMM D5G9D4_TUBMM D5G9D4_TUBMM D5G9H2_TUBMM D5G9H2_TUBMM D5G9H5_TUBMM D5G9H5_TUBMM D5G9K1_TUBMM D5G9K1_TUBMM D5G9W7_TUBMM D5G9W7_TUBMM D5GA17_TUBMM D5GA17_TUBMM D5GA46_TUBMM D5GA46_TUBMM D5GA69_TUBMM D5GA69_TUBMM D5GA79_TUBMM D5GA79_TUBMM D5GAS5_TUBMM D5GAS5_TUBMM D5GAW4_TUBMM D5GAW4_TUBMM D5GB06_TUBMM D5GB06_TUBMM D5GB17_TUBMM D5GB17_TUBMM D5GB52_TUBMM D5GB52_TUBMM D5GB65_TUBMM D5GB65_TUBMM D5GB88_TUBMM D5GB88_TUBMM D5GBI2_TUBMM D5GBI2_TUBMM D5GBK0_TUBMM D5GBK0_TUBMM D5GC67_TUBMM D5GC67_TUBMM D5GC74_TUBMM D5GC74_TUBMM D5GCC5_TUBMM D5GCC5_TUBMM D5GCF3_TUBMM D5GCF3_TUBMM D5GCS6_TUBMM D5GCS6_TUBMM D5GCT6_TUBMM D5GCT6_TUBMM D5GD20_TUBMM D5GD20_TUBMM D5GD47_TUBMM D5GD47_TUBMM MED6 MED6 D5GDE1_TUBMM D5GDE1_TUBMM D5GDE9_TUBMM D5GDE9_TUBMM D5GDH3_TUBMM D5GDH3_TUBMM D5GDH6_TUBMM D5GDH6_TUBMM D5GDI7_TUBMM D5GDI7_TUBMM D5GDP2_TUBMM D5GDP2_TUBMM D5GDP6_TUBMM D5GDP6_TUBMM D5GDS7_TUBMM D5GDS7_TUBMM D5GDS8_TUBMM D5GDS8_TUBMM D5GE74_TUBMM D5GE74_TUBMM D5GEA1_TUBMM D5GEA1_TUBMM D5GEA3_TUBMM D5GEA3_TUBMM D5GEB5_TUBMM D5GEB5_TUBMM D5GEE6_TUBMM D5GEE6_TUBMM D5GEE7_TUBMM D5GEE7_TUBMM D5GEG0_TUBMM D5GEG0_TUBMM D5GEJ8_TUBMM D5GEJ8_TUBMM D5GEM7_TUBMM D5GEM7_TUBMM D5GEV5_TUBMM D5GEV5_TUBMM MED4 MED4 D5GF95_TUBMM D5GF95_TUBMM D5GFD6_TUBMM D5GFD6_TUBMM D5GFE4_TUBMM D5GFE4_TUBMM D5GFS9_TUBMM D5GFS9_TUBMM D5GFT2_TUBMM D5GFT2_TUBMM D5GFX1_TUBMM D5GFX1_TUBMM D5GFZ4_TUBMM D5GFZ4_TUBMM D5GG75_TUBMM D5GG75_TUBMM D5GGR7_TUBMM D5GGR7_TUBMM D5GGS0_TUBMM D5GGS0_TUBMM D5GH70_TUBMM D5GH70_TUBMM MED10 MED10 D5GH98_TUBMM D5GH98_TUBMM MED11 MED11 MED9 MED9 D5GHT3_TUBMM D5GHT3_TUBMM D5GHT6_TUBMM D5GHT6_TUBMM D5GHW4_TUBMM D5GHW4_TUBMM D5GIJ0_TUBMM D5GIJ0_TUBMM D5GIM4_TUBMM D5GIM4_TUBMM D5GIN2_TUBMM D5GIN2_TUBMM D5GIQ1_TUBMM D5GIQ1_TUBMM D5GIS0_TUBMM D5GIS0_TUBMM D5GIS2_TUBMM D5GIS2_TUBMM D5GJ86_TUBMM D5GJ86_TUBMM D5GJ94_TUBMM D5GJ94_TUBMM D5GJ97_TUBMM D5GJ97_TUBMM D5GJ99_TUBMM D5GJ99_TUBMM MED8 MED8 D5GJI2_TUBMM D5GJI2_TUBMM D5GJJ1_TUBMM D5GJJ1_TUBMM D5GJJ3_TUBMM D5GJJ3_TUBMM D5GJJ8_TUBMM D5GJJ8_TUBMM D5GJJ9_TUBMM D5GJJ9_TUBMM D5GJM0_TUBMM D5GJM0_TUBMM D5GJN7_TUBMM D5GJN7_TUBMM D5GJN8_TUBMM D5GJN8_TUBMM D5GJX7_TUBMM D5GJX7_TUBMM MED19 MED19 D5GK17_TUBMM D5GK17_TUBMM D5GK28_TUBMM D5GK28_TUBMM D5GK82_TUBMM D5GK82_TUBMM D5GKA9_TUBMM D5GKA9_TUBMM D5GKC0_TUBMM D5GKC0_TUBMM D5GKH8_TUBMM D5GKH8_TUBMM D5GKL8_TUBMM D5GKL8_TUBMM D5GKM4_TUBMM D5GKM4_TUBMM D5GKT6_TUBMM D5GKT6_TUBMM D5GKX1_TUBMM D5GKX1_TUBMM D5GKX5_TUBMM D5GKX5_TUBMM D5GL64_TUBMM D5GL64_TUBMM D5GLH5_TUBMM D5GLH5_TUBMM D5GLS3_TUBMM D5GLS3_TUBMM D5GLV0_TUBMM D5GLV0_TUBMM D5GLV5_TUBMM D5GLV5_TUBMM D5GM43_TUBMM D5GM43_TUBMM D5GM47_TUBMM D5GM47_TUBMM D5GM48_TUBMM D5GM48_TUBMM D5GM63_TUBMM D5GM63_TUBMM D5GMC8_TUBMM D5GMC8_TUBMM D5GME3_TUBMM D5GME3_TUBMM D5GMK1_TUBMM D5GMK1_TUBMM D5GMM6_TUBMM D5GMM6_TUBMM D5GN25_TUBMM D5GN25_TUBMM D5GN86_TUBMM D5GN86_TUBMM D5GNB6_TUBMM D5GNB6_TUBMM D5GNC1_TUBMM D5GNC1_TUBMM D5GND9_TUBMM D5GND9_TUBMM D5GNE3_TUBMM D5GNE3_TUBMM D5GNK2_TUBMM D5GNK2_TUBMM D5GNK6_TUBMM D5GNK6_TUBMM D5GNM5_TUBMM D5GNM5_TUBMM D5GNN0_TUBMM D5GNN0_TUBMM D5GNN4_TUBMM D5GNN4_TUBMM D5GNP0_TUBMM D5GNP0_TUBMM D5GP56_TUBMM D5GP56_TUBMM D5GP57_TUBMM D5GP57_TUBMM D5GPE4_TUBMM D5GPE4_TUBMM D5GPG2_TUBMM D5GPG2_TUBMM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D5G3X4_TUBMMGPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (320 aa)
D5G437_TUBMMUncharacterized protein. (681 aa)
D5G445_TUBMMUncharacterized protein. (178 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (248 aa)
MED5Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1005 aa)
D5G4U3_TUBMMBTB domain-containing protein. (324 aa)
D5G578_TUBMMMediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (229 aa)
D5G5S2_TUBMMUncharacterized protein. (1221 aa)
D5G5S6_TUBMMUncharacterized protein; Belongs to the cyclin family. (367 aa)
D5G5X0_TUBMMTAF domain-containing protein. (472 aa)
D5G5X6_TUBMMBTP domain-containing protein. (143 aa)
D5G674_TUBMMUncharacterized protein; Belongs to the RNA polymerase beta chain family. (620 aa)
D5G675_TUBMMUncharacterized protein. (436 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (608 aa)
D5G763_TUBMMRPOLD domain-containing protein. (340 aa)
D5G7D7_TUBMMZn(2)-C6 fungal-type domain-containing protein. (648 aa)
D5G7D8_TUBMMZn(2)-C6 fungal-type domain-containing protein. (804 aa)
D5G7P9_TUBMMUncharacterized protein. (1019 aa)
D5G7Q2_TUBMMUncharacterized protein. (174 aa)
D5G7T0_TUBMMUncharacterized protein. (826 aa)
D5G7W3_TUBMMHTH TFE/IIEalpha-type domain-containing protein. (454 aa)
D5G7W7_TUBMMUncharacterized protein. (376 aa)
D5G821_TUBMMBTB domain-containing protein. (862 aa)
D5G825_TUBMMUncharacterized protein. (436 aa)
D5G879_TUBMMUncharacterized protein. (427 aa)
D5G8A7_TUBMMRNA_pol_L_2 domain-containing protein. (119 aa)
D5G8D7_TUBMMDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (544 aa)
D5G8D8_TUBMMUncharacterized protein. (1056 aa)
D5G8G1_TUBMMTranscription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (229 aa)
D5G8S6_TUBMMUncharacterized protein. (631 aa)
D5G8Y9_TUBMMUncharacterized protein. (581 aa)
D5G8Z9_TUBMMUncharacterized protein. (269 aa)
D5G915_TUBMMUncharacterized protein. (120 aa)
D5G963_TUBMMUncharacterized protein. (253 aa)
D5G997_TUBMMZn(2)-C6 fungal-type domain-containing protein. (712 aa)
D5G9D4_TUBMMUncharacterized protein. (187 aa)
D5G9H2_TUBMMUncharacterized protein. (758 aa)
D5G9H5_TUBMMDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (111 aa)
D5G9K1_TUBMMUncharacterized protein. (156 aa)
D5G9W7_TUBMMHMG box domain-containing protein. (310 aa)
D5GA17_TUBMMUncharacterized protein; Belongs to the cytochrome P450 family. (457 aa)
D5GA46_TUBMMUncharacterized protein. (576 aa)
D5GA69_TUBMMProtein kinase domain-containing protein. (592 aa)
D5GA79_TUBMMFCP1 homology domain-containing protein. (507 aa)
D5GAS5_TUBMMRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (643 aa)
D5GAW4_TUBMMSANT domain-containing protein. (664 aa)
D5GB06_TUBMMRepressor of RNA polymerase III transcription MAF1; Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (276 aa)
D5GB17_TUBMMProtein kinase domain-containing protein. (453 aa)
D5GB52_TUBMMTAFII55_N domain-containing protein. (457 aa)
D5GB65_TUBMMDUF3591 domain-containing protein. (1084 aa)
D5GB88_TUBMMC3H1-type domain-containing protein. (536 aa)
D5GBI2_TUBMMMed12 domain-containing protein. (1449 aa)
D5GBK0_TUBMMUncharacterized protein. (336 aa)
D5GC67_TUBMMBUD22 domain-containing protein. (129 aa)
D5GC74_TUBMMMediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (258 aa)
D5GCC5_TUBMMUncharacterized protein. (358 aa)
D5GCF3_TUBMMMediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (118 aa)
D5GCS6_TUBMMIwr1 domain-containing protein. (523 aa)
D5GCT6_TUBMMTranscription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (122 aa)
D5GD20_TUBMMTranscription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1419 aa)
D5GD47_TUBMMUncharacterized protein. (373 aa)
MED6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (320 aa)
D5GDE1_TUBMMRNA_pol_L_2 domain-containing protein. (105 aa)
D5GDE9_TUBMMTranscription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (228 aa)
D5GDH3_TUBMMMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (218 aa)
D5GDH6_TUBMMUncharacterized protein. (337 aa)
D5GDI7_TUBMMUncharacterized protein. (514 aa)
D5GDP2_TUBMMHelicase ATP-binding domain-containing protein. (807 aa)
D5GDP6_TUBMMHIT domain-containing protein. (135 aa)
D5GDS7_TUBMMUncharacterized protein. (442 aa)
D5GDS8_TUBMMRNA_pol_Rpb1_5 domain-containing protein. (449 aa)
D5GE74_TUBMMUncharacterized protein; Belongs to the cyclin family. (405 aa)
D5GEA1_TUBMMTranscription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (114 aa)
D5GEA3_TUBMMHMG box domain-containing protein. (103 aa)
D5GEB5_TUBMMCyclin N-terminal domain-containing protein. (238 aa)
D5GEE6_TUBMMUncharacterized protein. (434 aa)
D5GEE7_TUBMMUncharacterized protein. (404 aa)
D5GEG0_TUBMMSulfatase domain-containing protein. (573 aa)
D5GEJ8_TUBMMUncharacterized protein. (1181 aa)
D5GEM7_TUBMMUncharacterized protein. (418 aa)
D5GEV5_TUBMMTranscription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (115 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (260 aa)
D5GF95_TUBMMMediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (930 aa)
D5GFD6_TUBMMBTB domain-containing protein. (220 aa)
D5GFE4_TUBMMZZ-type domain-containing protein. (381 aa)
D5GFS9_TUBMMUncharacterized protein. (232 aa)
D5GFT2_TUBMMUncharacterized protein. (980 aa)
D5GFX1_TUBMMUncharacterized protein. (468 aa)
D5GFZ4_TUBMMmRNA_triPase domain-containing protein. (535 aa)
D5GG75_TUBMMTYR_PHOSPHATASE_2 domain-containing protein. (593 aa)
D5GGR7_TUBMMRNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (896 aa)
D5GGS0_TUBMMHMG box domain-containing protein. (621 aa)
D5GH70_TUBMMTFIIB-type domain-containing protein. (346 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (152 aa)
D5GH98_TUBMMMYND-type domain-containing protein. (601 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (139 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (115 aa)
D5GHT3_TUBMMrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (294 aa)
D5GHT6_TUBMMGPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (374 aa)
D5GHW4_TUBMMNAD_binding_6 domain-containing protein. (807 aa)
D5GIJ0_TUBMMUncharacterized protein. (501 aa)
D5GIM4_TUBMMTyosinase_C domain-containing protein. (300 aa)
D5GIN2_TUBMMRING-type domain-containing protein. (373 aa)
D5GIQ1_TUBMMTranscription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (203 aa)
D5GIS0_TUBMMGPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (277 aa)
D5GIS2_TUBMMUncharacterized protein. (83 aa)
D5GJ86_TUBMMUncharacterized protein. (1269 aa)
D5GJ94_TUBMMUncharacterized protein. (357 aa)
D5GJ97_TUBMMUncharacterized protein. (105 aa)
D5GJ99_TUBMMUncharacterized protein. (110 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (282 aa)
D5GJI2_TUBMMRTR1-type domain-containing protein. (314 aa)
D5GJJ1_TUBMMCID domain-containing protein. (244 aa)
D5GJJ3_TUBMMDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
D5GJJ8_TUBMMUncharacterized protein; Belongs to the RNA polymerase beta chain family. (660 aa)
D5GJJ9_TUBMMUncharacterized protein. (422 aa)
D5GJM0_TUBMMmRNA cap 0 methyltransferase domain-containing protein. (655 aa)
D5GJN7_TUBMMUncharacterized protein. (434 aa)
D5GJN8_TUBMMUncharacterized protein; Belongs to the RNA polymerase beta chain family. (660 aa)
D5GJX7_TUBMMUncharacterized protein. (471 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (351 aa)
D5GK17_TUBMMUncharacterized protein. (695 aa)
D5GK28_TUBMMTAF4 domain-containing protein. (443 aa)
D5GK82_TUBMMGeneral transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (469 aa)
D5GKA9_TUBMMTFIIS N-terminal domain-containing protein. (395 aa)
D5GKC0_TUBMMRPOLD domain-containing protein. (377 aa)
D5GKH8_TUBMMUncharacterized protein. (422 aa)
D5GKL8_TUBMMUncharacterized protein. (194 aa)
D5GKM4_TUBMMRNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (460 aa)
D5GKT6_TUBMMUncharacterized protein. (1025 aa)
D5GKX1_TUBMMDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (303 aa)
D5GKX5_TUBMMUncharacterized protein. (269 aa)
D5GL64_TUBMMUncharacterized protein. (390 aa)
D5GLH5_TUBMMmRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (388 aa)
D5GLS3_TUBMMUncharacterized protein. (595 aa)
D5GLV0_TUBMMUncharacterized protein. (241 aa)
D5GLV5_TUBMMUncharacterized protein. (690 aa)
D5GM43_TUBMMUncharacterized protein. (616 aa)
D5GM47_TUBMMUncharacterized protein. (370 aa)
D5GM48_TUBMMTranscription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1054 aa)
D5GM63_TUBMMS1 motif domain-containing protein. (180 aa)
D5GMC8_TUBMMUncharacterized protein. (73 aa)
D5GME3_TUBMMHelicase ATP-binding domain-containing protein. (748 aa)
D5GMK1_TUBMMCYCLIN domain-containing protein; Belongs to the cyclin family. (416 aa)
D5GMM6_TUBMMCDC73_C domain-containing protein. (415 aa)
D5GN25_TUBMMTFIID_20kDa domain-containing protein. (725 aa)
D5GN86_TUBMMFACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (570 aa)
D5GNB6_TUBMMProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (378 aa)
D5GNC1_TUBMMUncharacterized protein. (618 aa)
D5GND9_TUBMMDNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1416 aa)
D5GNE3_TUBMMTranscription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (762 aa)
D5GNK2_TUBMMUncharacterized protein. (76 aa)
D5GNK6_TUBMMUncharacterized protein. (220 aa)
D5GNM5_TUBMMTFIIB-type domain-containing protein. (553 aa)
D5GNN0_TUBMMRPOL4c domain-containing protein. (146 aa)
D5GNN4_TUBMMUncharacterized protein. (524 aa)
D5GNP0_TUBMMTranscription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (285 aa)
D5GP56_TUBMMTAFII28 domain-containing protein. (258 aa)
D5GP57_TUBMMUncharacterized protein. (217 aa)
D5GPE4_TUBMMProtein kinase domain-containing protein. (1122 aa)
D5GPG2_TUBMMPlus3 domain-containing protein. (567 aa)
Your Current Organism:
Tuber melanosporum
NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28
Server load: medium (48%) [HD]