(32 nodes) Ubiquitin conjugating enzyme activity, and Ubiquitin domain network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G542_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	D5G5K3_TUBMM	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1011 aa)
	D5G5X8_TUBMM	Uncharacterized protein. (449 aa)
	D5G6L1_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein. (1124 aa)
	D5G717_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein. (152 aa)
	D5G737_TUBMM	HECT domain-containing protein. (1545 aa)
	D5G7T2_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	D5G832_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein. (293 aa)
	D5G836_TUBMM	Uncharacterized protein. (662 aa)
	D5G9F4_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein. (139 aa)
	D5GAD5_TUBMM	E3 ubiquitin protein ligase. (722 aa)
	D5GAF0_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (236 aa)
	D5GB50_TUBMM	Uncharacterized protein. (205 aa)
	D5GC14_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein. (292 aa)
	D5GC42_TUBMM	Uncharacterized protein. (256 aa)
	D5GC77_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
	D5GCL6_TUBMM	OTU domain-containing protein. (474 aa)
	D5GD34_TUBMM	RBR-type E3 ubiquitin transferase. (507 aa)
	D5GE07_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
	D5GEZ2_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	D5GFA2_TUBMM	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (2122 aa)
	D5GFJ3_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (168 aa)
	D5GFJ7_TUBMM	HECT domain-containing protein. (1810 aa)
	D5GGQ0_TUBMM	Ubiquitin-like domain-containing protein. (153 aa)
	D5GH69_TUBMM	Uncharacterized protein. (306 aa)
	D5GJ01_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein. (153 aa)
	D5GKA5_TUBMM	Ubiquitin-like domain-containing protein. (160 aa)
	D5GKI2_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (253 aa)
	D5GM37_TUBMM	Uncharacterized protein. (254 aa)
	D5GN56_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein. (166 aa)
	D5GNE8_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein. (1134 aa)
	D5GP79_TUBMM	E3 ubiquitin-protein ligase. (739 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G542_TUBMM	D5G5K3_TUBMM	D5G542	D5G5K3	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.	0.983
D5G542_TUBMM	D5G6L1_TUBMM	D5G542	D5G6L1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.640
D5G542_TUBMM	D5G717_TUBMM	D5G542	D5G717	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.602
D5G542_TUBMM	D5G737_TUBMM	D5G542	D5G737	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	HECT domain-containing protein.	0.429
D5G542_TUBMM	D5G7T2_TUBMM	D5G542	D5G7T2	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.592
D5G542_TUBMM	D5G832_TUBMM	D5G542	D5G832	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.671
D5G542_TUBMM	D5G9F4_TUBMM	D5G542	D5G9F4	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.888
D5G542_TUBMM	D5GAD5_TUBMM	D5G542	D5GAD5	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin protein ligase.	0.457
D5G542_TUBMM	D5GAF0_TUBMM	D5G542	D5GAF0	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.601
D5G542_TUBMM	D5GB50_TUBMM	D5G542	D5GB50	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.840
D5G542_TUBMM	D5GC14_TUBMM	D5G542	D5GC14	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.438
D5G542_TUBMM	D5GC42_TUBMM	D5G542	D5GC42	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.882
D5G542_TUBMM	D5GC77_TUBMM	D5G542	D5GC77	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.690
D5G542_TUBMM	D5GCL6_TUBMM	D5G542	D5GCL6	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	OTU domain-containing protein.	0.923
D5G542_TUBMM	D5GD34_TUBMM	D5G542	D5GD34	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	RBR-type E3 ubiquitin transferase.	0.467
D5G542_TUBMM	D5GE07_TUBMM	D5G542	D5GE07	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.612
D5G542_TUBMM	D5GEZ2_TUBMM	D5G542	D5GEZ2	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.762
D5G542_TUBMM	D5GFA2_TUBMM	D5G542	D5GFA2	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.	0.447
D5G542_TUBMM	D5GFJ7_TUBMM	D5G542	D5GFJ7	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	HECT domain-containing protein.	0.445
D5G542_TUBMM	D5GGQ0_TUBMM	D5G542	D5GGQ0	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-like domain-containing protein.	0.688