(14 nodes) Outer mitochondrial membrane protein complex, and Pore complex network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G420_TUBMM	Uncharacterized protein. (288 aa)
	D5G5T8_TUBMM	Uncharacterized protein. (373 aa)
	MDM12	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (417 aa)
	D5G831_TUBMM	Bac_surface_Ag domain-containing protein. (506 aa)
	D5G9J2_TUBMM	Uncharacterized protein. (142 aa)
	MMM1	Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (353 aa)
	D5GB56_TUBMM	Uncharacterized protein. (297 aa)
	D5GBI9_TUBMM	Uncharacterized protein. (153 aa)
	D5GDH5_TUBMM	Uncharacterized protein. (604 aa)
	D5GF68_TUBMM	Uncharacterized protein. (472 aa)
	D5GFL2_TUBMM	Uncharacterized protein. (356 aa)
	MDM10	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (371 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (554 aa)
	D5GPS3_TUBMM	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (789 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G420_TUBMM	D5G5T8_TUBMM	D5G420	D5G5T8	Uncharacterized protein.	Uncharacterized protein.	0.955
D5G420_TUBMM	D5G831_TUBMM	D5G420	D5G831	Uncharacterized protein.	Bac_surface_Ag domain-containing protein.	0.752
D5G420_TUBMM	D5G9J2_TUBMM	D5G420	D5G9J2	Uncharacterized protein.	Uncharacterized protein.	0.768
D5G420_TUBMM	D5GBI9_TUBMM	D5G420	D5GBI9	Uncharacterized protein.	Uncharacterized protein.	0.917
D5G420_TUBMM	D5GDH5_TUBMM	D5G420	D5GDH5	Uncharacterized protein.	Uncharacterized protein.	0.865
D5G420_TUBMM	D5GFL2_TUBMM	D5G420	D5GFL2	Uncharacterized protein.	Uncharacterized protein.	0.817
D5G420_TUBMM	D5GPS3_TUBMM	D5G420	D5GPS3	Uncharacterized protein.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.910
D5G420_TUBMM	MDM10	D5G420	D5GJQ6	Uncharacterized protein.	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	0.526
D5G420_TUBMM	MDM12	D5G420	D5G665	Uncharacterized protein.	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	0.544
D5G5T8_TUBMM	D5G420_TUBMM	D5G5T8	D5G420	Uncharacterized protein.	Uncharacterized protein.	0.955
D5G5T8_TUBMM	D5G831_TUBMM	D5G5T8	D5G831	Uncharacterized protein.	Bac_surface_Ag domain-containing protein.	0.974
D5G5T8_TUBMM	D5G9J2_TUBMM	D5G5T8	D5G9J2	Uncharacterized protein.	Uncharacterized protein.	0.999
D5G5T8_TUBMM	D5GB56_TUBMM	D5G5T8	D5GB56	Uncharacterized protein.	Uncharacterized protein.	0.897
D5G5T8_TUBMM	D5GBI9_TUBMM	D5G5T8	D5GBI9	Uncharacterized protein.	Uncharacterized protein.	0.991
D5G5T8_TUBMM	D5GDH5_TUBMM	D5G5T8	D5GDH5	Uncharacterized protein.	Uncharacterized protein.	0.979
D5G5T8_TUBMM	D5GF68_TUBMM	D5G5T8	D5GF68	Uncharacterized protein.	Uncharacterized protein.	0.961
D5G5T8_TUBMM	D5GFL2_TUBMM	D5G5T8	D5GFL2	Uncharacterized protein.	Uncharacterized protein.	0.694
D5G5T8_TUBMM	D5GPS3_TUBMM	D5G5T8	D5GPS3	Uncharacterized protein.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.484
D5G5T8_TUBMM	MDM10	D5G5T8	D5GJQ6	Uncharacterized protein.	Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]	0.850
D5G5T8_TUBMM	MDM12	D5G5T8	D5G665	Uncharacterized protein.	Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]	0.652