(70 nodes) Intra-Golgi and retrograde Golgi-to-ER traffic, and SNAP receptor activity network (Tuber melanosporum)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G3U7_TUBMM	t-SNARE coiled-coil homology domain-containing protein. (254 aa)
	D5G3X0_TUBMM	Vps54 domain-containing protein. (984 aa)
	D5G544_TUBMM	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. (395 aa)
	D5G545_TUBMM	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events. (250 aa)
	D5G584_TUBMM	Uncharacterized protein. (742 aa)
	D5G5D8_TUBMM	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (830 aa)
	D5G5E5_TUBMM	Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (228 aa)
	D5G5V2_TUBMM	Uncharacterized protein. (237 aa)
	D5G5W9_TUBMM	Uncharacterized protein. (910 aa)
	D5G6S2_TUBMM	t-SNARE coiled-coil homology domain-containing protein. (316 aa)
	D5G750_TUBMM	Uncharacterized protein. (854 aa)
	D5G7B9_TUBMM	Vps53_N domain-containing protein. (857 aa)
	D5G7E2_TUBMM	Uncharacterized protein. (304 aa)
	D5G7H9_TUBMM	Uncharacterized protein; Belongs to the synaptobrevin family. (214 aa)
	D5G7N6_TUBMM	V-SNARE coiled-coil homology domain-containing protein. (118 aa)
	D5G867_TUBMM	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (681 aa)
	D5G875_TUBMM	Uncharacterized protein; Belongs to the AAA ATPase family. (560 aa)
	D5G885_TUBMM	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1096 aa)
	D5G8R8_TUBMM	RIC1 domain-containing protein. (1105 aa)
	D5G964_TUBMM	Uncharacterized protein. (306 aa)
	D5G9J8_TUBMM	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (879 aa)
	D5G9K5_TUBMM	GOLD domain-containing protein. (211 aa)
	D5GA07_TUBMM	TMF_TATA_bd domain-containing protein. (746 aa)
	D5GAB5_TUBMM	Uncharacterized protein. (291 aa)
	D5GAG6_TUBMM	Uncharacterized protein. (307 aa)
	D5GAM2_TUBMM	GOLD domain-containing protein. (220 aa)
	D5GB01_TUBMM	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1212 aa)
	D5GB27_TUBMM	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (168 aa)
	D5GB39_TUBMM	Uncharacterized protein. (787 aa)
	D5GBD1_TUBMM	Uncharacterized protein. (208 aa)
	D5GBK4_TUBMM	Uncharacterized protein. (1002 aa)
	D5GBL1_TUBMM	t-SNARE coiled-coil homology domain-containing protein. (261 aa)
	D5GC37_TUBMM	Uncharacterized protein. (407 aa)
	D5GC85_TUBMM	Arf-GAP domain-containing protein. (357 aa)
	D5GCR7_TUBMM	ATPase_AAA_core domain-containing protein. (183 aa)
	D5GCR8_TUBMM	Uncharacterized protein. (117 aa)
	D5GD19_TUBMM	Dsl1_C domain-containing protein. (848 aa)
	D5GD39_TUBMM	Uncharacterized protein. (188 aa)
	D5GE00_TUBMM	Uncharacterized protein. (295 aa)
	D5GE39_TUBMM	Arf-GAP domain-containing protein. (464 aa)
	D5GEU0_TUBMM	t-SNARE coiled-coil homology domain-containing protein. (249 aa)
	D5GFF3_TUBMM	Uncharacterized protein. (332 aa)
	D5GFJ6_TUBMM	Uncharacterized protein. (61 aa)
	D5GG33_TUBMM	Uncharacterized protein. (203 aa)
	D5GH62_TUBMM	Uncharacterized protein. (483 aa)
	D5GHJ1_TUBMM	GOLD domain-containing protein. (202 aa)
	D5GHK3_TUBMM	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
	D5GHK7_TUBMM	Uncharacterized protein. (257 aa)
	D5GHX8_TUBMM	AAA domain-containing protein. (958 aa)
	D5GIR1_TUBMM	t-SNARE coiled-coil homology domain-containing protein. (226 aa)
	D5GIW0_TUBMM	Thioredoxin reductase. (344 aa)
	D5GJ84_TUBMM	SEC7 domain-containing protein. (1841 aa)
	D5GJQ9_TUBMM	Uncharacterized protein. (703 aa)
	D5GJS7_TUBMM	Uncharacterized protein. (766 aa)
	D5GK64_TUBMM	ER lumen protein-retaining receptor. (213 aa)
	D5GK94_TUBMM	Cog4 domain-containing protein. (846 aa)
	D5GKC9_TUBMM	t-SNARE coiled-coil homology domain-containing protein. (212 aa)
	D5GKK0_TUBMM	t-SNARE coiled-coil homology domain-containing protein. (346 aa)
	D5GKL2_TUBMM	SEC7 domain-containing protein. (1486 aa)
	D5GLI1_TUBMM	Uncharacterized protein. (343 aa)
	D5GLI2_TUBMM	Uncharacterized protein. (903 aa)
	D5GLM6_TUBMM	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (364 aa)
	D5GM89_TUBMM	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	D5GN24_TUBMM	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (292 aa)
	D5GNB4_TUBMM	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (950 aa)
	D5GNU5_TUBMM	Uncharacterized protein; Belongs to the synaptobrevin family. (238 aa)
	D5GP22_TUBMM	t-SNARE coiled-coil homology domain-containing protein. (356 aa)
	D5GPA3_TUBMM	GOLD domain-containing protein. (223 aa)
	D5GPA9_TUBMM	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (279 aa)
	D5GPI0_TUBMM	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (198 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G3U7_TUBMM	D5G3X0_TUBMM	D5G3U7	D5G3X0	t-SNARE coiled-coil homology domain-containing protein.	Vps54 domain-containing protein.	0.864
D5G3U7_TUBMM	D5G544_TUBMM	D5G3U7	D5G544	t-SNARE coiled-coil homology domain-containing protein.	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	0.675
D5G3U7_TUBMM	D5G545_TUBMM	D5G3U7	D5G545	t-SNARE coiled-coil homology domain-containing protein.	Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.	0.675
D5G3U7_TUBMM	D5G584_TUBMM	D5G3U7	D5G584	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.638
D5G3U7_TUBMM	D5G5E5_TUBMM	D5G3U7	D5G5E5	t-SNARE coiled-coil homology domain-containing protein.	Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.	0.903
D5G3U7_TUBMM	D5G5V2_TUBMM	D5G3U7	D5G5V2	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.590
D5G3U7_TUBMM	D5G6S2_TUBMM	D5G3U7	D5G6S2	t-SNARE coiled-coil homology domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein.	0.602
D5G3U7_TUBMM	D5G750_TUBMM	D5G3U7	D5G750	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.604
D5G3U7_TUBMM	D5G7B9_TUBMM	D5G3U7	D5G7B9	t-SNARE coiled-coil homology domain-containing protein.	Vps53_N domain-containing protein.	0.760
D5G3U7_TUBMM	D5G7H9_TUBMM	D5G3U7	D5G7H9	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.987
D5G3U7_TUBMM	D5G7N6_TUBMM	D5G3U7	D5G7N6	t-SNARE coiled-coil homology domain-containing protein.	V-SNARE coiled-coil homology domain-containing protein.	0.998
D5G3U7_TUBMM	D5G867_TUBMM	D5G3U7	D5G867	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.547
D5G3U7_TUBMM	D5G8R8_TUBMM	D5G3U7	D5G8R8	t-SNARE coiled-coil homology domain-containing protein.	RIC1 domain-containing protein.	0.612
D5G3U7_TUBMM	D5G964_TUBMM	D5G3U7	D5G964	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.597
D5G3U7_TUBMM	D5GAB5_TUBMM	D5G3U7	D5GAB5	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.954
D5G3U7_TUBMM	D5GBD1_TUBMM	D5G3U7	D5GBD1	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.834
D5G3U7_TUBMM	D5GBL1_TUBMM	D5G3U7	D5GBL1	t-SNARE coiled-coil homology domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein.	0.991
D5G3U7_TUBMM	D5GE00_TUBMM	D5G3U7	D5GE00	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.522
D5G3U7_TUBMM	D5GEU0_TUBMM	D5G3U7	D5GEU0	t-SNARE coiled-coil homology domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein.	0.736
D5G3U7_TUBMM	D5GG33_TUBMM	D5G3U7	D5GG33	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.625