(46 nodes) Mixed, incl. Amino acids regulate mTORC1, and Energy dependent regulation of mTOR by LKB1-AMPK network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G5N0_TUBMM	Protein kinase domain-containing protein. (716 aa)
	D5G615_TUBMM	Uncharacterized protein. (120 aa)
	D5G6B1_TUBMM	Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (264 aa)
	D5G6J3_TUBMM	Uncharacterized protein. (1301 aa)
	D5G713_TUBMM	Uncharacterized protein. (587 aa)
	D5G7T3_TUBMM	Uncharacterized protein. (1307 aa)
	D5G7Z3_TUBMM	WD_REPEATS_REGION domain-containing protein. (1040 aa)
	D5G7Z4_TUBMM	Raptor_N domain-containing protein. (191 aa)
	D5G8C4_TUBMM	Uncharacterized protein. (995 aa)
	D5G968_TUBMM	Protein kinase domain-containing protein. (996 aa)
	D5G9F0_TUBMM	Uncharacterized protein. (687 aa)
	D5G9K2_TUBMM	4-nitrophenylphosphatase. (294 aa)
	D5G9X0_TUBMM	Uncharacterized protein. (450 aa)
	D5GA67_TUBMM	WAPL domain-containing protein. (990 aa)
	D5GA68_TUBMM	Uncharacterized protein. (186 aa)
	D5GAA1_TUBMM	Protein kinase domain-containing protein. (606 aa)
	D5GAD6_TUBMM	Rap-GAP domain-containing protein. (1557 aa)
	D5GAM8_TUBMM	Non-specific serine/threonine protein kinase. (551 aa)
	D5GB54_TUBMM	Uncharacterized protein. (301 aa)
	D5GBM4_TUBMM	Zinc_ribbon_16 domain-containing protein. (981 aa)
	D5GCP9_TUBMM	Uncharacterized protein. (349 aa)
	D5GDW6_TUBMM	UDENN FLCN/SMCR8-type domain-containing protein. (410 aa)
	D5GEJ5_TUBMM	Protein kinase domain-containing protein. (484 aa)
	D5GEU2_TUBMM	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (939 aa)
	D5GFN7_TUBMM	Uncharacterized protein. (521 aa)
	D5GG76_TUBMM	WD_REPEATS_REGION domain-containing protein. (1073 aa)
	D5GGE6_TUBMM	AMPK1_CBM domain-containing protein. (525 aa)
	D5GGK7_TUBMM	Uncharacterized protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (433 aa)
	D5GGT1_TUBMM	Uncharacterized protein. (642 aa)
	D5GGY9_TUBMM	Uncharacterized protein. (169 aa)
	D5GH81_TUBMM	DUF1752 domain-containing protein. (575 aa)
	D5GHJ4_TUBMM	AMPKBI domain-containing protein. (456 aa)
	D5GI65_TUBMM	Protein kinase domain-containing protein. (772 aa)
	D5GJ96_TUBMM	Uncharacterized protein. (350 aa)
	D5GJB5_TUBMM	Uncharacterized protein. (285 aa)
	D5GJJ6_TUBMM	Uncharacterized protein. (224 aa)
	D5GJL9_TUBMM	Non-specific serine/threonine protein kinase. (602 aa)
	D5GJQ0_TUBMM	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2332 aa)
	D5GKT4_TUBMM	Uncharacterized protein. (510 aa)
	D5GL83_TUBMM	Uncharacterized protein. (402 aa)
	D5GL84_TUBMM	DEP domain-containing protein. (1379 aa)
	D5GM08_TUBMM	Protein kinase domain-containing protein. (1027 aa)
	D5GNC2_TUBMM	Uncharacterized protein. (236 aa)
	D5GNS8_TUBMM	BTB domain-containing protein. (304 aa)
	D5GNU4_TUBMM	Uncharacterized protein. (459 aa)
	D5GPB3_TUBMM	WD_REPEATS_REGION domain-containing protein. (307 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G5N0_TUBMM	D5G7Z3_TUBMM	D5G5N0	D5G7Z3	Protein kinase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.457
D5G5N0_TUBMM	D5G7Z4_TUBMM	D5G5N0	D5G7Z4	Protein kinase domain-containing protein.	Raptor_N domain-containing protein.	0.457
D5G5N0_TUBMM	D5G968_TUBMM	D5G5N0	D5G968	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.458
D5G5N0_TUBMM	D5GAA1_TUBMM	D5G5N0	D5GAA1	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.433
D5G5N0_TUBMM	D5GAD6_TUBMM	D5G5N0	D5GAD6	Protein kinase domain-containing protein.	Rap-GAP domain-containing protein.	0.482
D5G5N0_TUBMM	D5GCP9_TUBMM	D5G5N0	D5GCP9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.472
D5G5N0_TUBMM	D5GGE6_TUBMM	D5G5N0	D5GGE6	Protein kinase domain-containing protein.	AMPK1_CBM domain-containing protein.	0.551
D5G5N0_TUBMM	D5GGK7_TUBMM	D5G5N0	D5GGK7	Protein kinase domain-containing protein.	Uncharacterized protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family.	0.555
D5G5N0_TUBMM	D5GGT1_TUBMM	D5G5N0	D5GGT1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.494
D5G5N0_TUBMM	D5GHJ4_TUBMM	D5G5N0	D5GHJ4	Protein kinase domain-containing protein.	AMPKBI domain-containing protein.	0.877
D5G5N0_TUBMM	D5GI65_TUBMM	D5G5N0	D5GI65	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.481
D5G5N0_TUBMM	D5GJ96_TUBMM	D5G5N0	D5GJ96	Protein kinase domain-containing protein.	Uncharacterized protein.	0.881
D5G5N0_TUBMM	D5GJQ0_TUBMM	D5G5N0	D5GJQ0	Protein kinase domain-containing protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.569
D5G5N0_TUBMM	D5GPB3_TUBMM	D5G5N0	D5GPB3	Protein kinase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.449
D5G615_TUBMM	D5G7T3_TUBMM	D5G615	D5G7T3	Uncharacterized protein.	Uncharacterized protein.	0.951
D5G615_TUBMM	D5G7Z3_TUBMM	D5G615	D5G7Z3	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.455
D5G615_TUBMM	D5G7Z4_TUBMM	D5G615	D5G7Z4	Uncharacterized protein.	Raptor_N domain-containing protein.	0.455
D5G615_TUBMM	D5G8C4_TUBMM	D5G615	D5G8C4	Uncharacterized protein.	Uncharacterized protein.	0.612
D5G615_TUBMM	D5G9F0_TUBMM	D5G615	D5G9F0	Uncharacterized protein.	Uncharacterized protein.	0.957
D5G615_TUBMM	D5GB54_TUBMM	D5G615	D5GB54	Uncharacterized protein.	Uncharacterized protein.	0.816