STRINGSTRING
D5G6H4_TUBMM D5G6H4_TUBMM D5G3X1_TUBMM D5G3X1_TUBMM D5G4C3_TUBMM D5G4C3_TUBMM D5G4H5_TUBMM D5G4H5_TUBMM MCM7 MCM7 D5G549_TUBMM D5G549_TUBMM D5G5G2_TUBMM D5G5G2_TUBMM D5G5J6_TUBMM D5G5J6_TUBMM D5G5R0_TUBMM D5G5R0_TUBMM D5G668_TUBMM D5G668_TUBMM D5G6Z1_TUBMM D5G6Z1_TUBMM D5G6Z2_TUBMM D5G6Z2_TUBMM D5G7R8_TUBMM D5G7R8_TUBMM D5G8U2_TUBMM D5G8U2_TUBMM D5G9H9_TUBMM D5G9H9_TUBMM D5GAB3_TUBMM D5GAB3_TUBMM D5GBC6_TUBMM D5GBC6_TUBMM D5GBK2_TUBMM D5GBK2_TUBMM D5GBQ9_TUBMM D5GBQ9_TUBMM D5GCG5_TUBMM D5GCG5_TUBMM D5GD77_TUBMM D5GD77_TUBMM D5GE03_TUBMM D5GE03_TUBMM D5GF81_TUBMM D5GF81_TUBMM D5GFC0_TUBMM D5GFC0_TUBMM D5GFX9_TUBMM D5GFX9_TUBMM D5GH25_TUBMM D5GH25_TUBMM D5GHA6_TUBMM D5GHA6_TUBMM D5GHI0_TUBMM D5GHI0_TUBMM D5GHM8_TUBMM D5GHM8_TUBMM D5GI23_TUBMM D5GI23_TUBMM D5GJT7_TUBMM D5GJT7_TUBMM D5GJZ6_TUBMM D5GJZ6_TUBMM D5GKB2_TUBMM D5GKB2_TUBMM D5GKT5_TUBMM D5GKT5_TUBMM D5GLJ2_TUBMM D5GLJ2_TUBMM D5GM32_TUBMM D5GM32_TUBMM D5GMT4_TUBMM D5GMT4_TUBMM D5GMZ3_TUBMM D5GMZ3_TUBMM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D5G6H4_TUBMMUncharacterized protein; Belongs to the PI3/PI4-kinase family. (2521 aa)
D5G3X1_TUBMMDNA helicase; Belongs to the MCM family. (720 aa)
D5G4C3_TUBMMUncharacterized protein. (898 aa)
D5G4H5_TUBMMUncharacterized protein. (186 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (783 aa)
D5G549_TUBMMHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (337 aa)
D5G5G2_TUBMMDouble-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (769 aa)
D5G5J6_TUBMMHTH APSES-type domain-containing protein. (363 aa)
D5G5R0_TUBMMCUE domain-containing protein. (986 aa)
D5G668_TUBMMAAA_23 domain-containing protein. (1345 aa)
D5G6Z1_TUBMMUncharacterized protein. (1003 aa)
D5G6Z2_TUBMMUncharacterized protein; Belongs to the RecA family. (265 aa)
D5G7R8_TUBMMRRM_3 domain-containing protein. (442 aa)
D5G8U2_TUBMMUncharacterized protein. (385 aa)
D5G9H9_TUBMMUncharacterized protein. (586 aa)
D5GAB3_TUBMMSAP domain-containing protein. (645 aa)
D5GBC6_TUBMMRif1_N domain-containing protein. (1764 aa)
D5GBK2_TUBMMDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (616 aa)
D5GBQ9_TUBMMReplication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (614 aa)
D5GCG5_TUBMMDNA helicase; Belongs to the MCM family. (772 aa)
D5GD77_TUBMMCheckpoint protein; Belongs to the HUS1 family. (287 aa)
D5GE03_TUBMMStc1 domain-containing protein. (277 aa)
D5GF81_TUBMMThreonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (435 aa)
D5GFC0_TUBMMATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (527 aa)
D5GFX9_TUBMMKu domain-containing protein. (665 aa)
D5GH25_TUBMMUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1684 aa)
D5GHA6_TUBMMHistone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (377 aa)
D5GHI0_TUBMMHD domain-containing protein. (214 aa)
D5GHM8_TUBMMCULLIN_2 domain-containing protein; Belongs to the cullin family. (873 aa)
D5GI23_TUBMMUncharacterized protein. (967 aa)
D5GJT7_TUBMMDRMBL domain-containing protein. (950 aa)
D5GJZ6_TUBMMUncharacterized protein. (676 aa)
D5GKB2_TUBMMTelomere_reg-2 domain-containing protein. (962 aa)
D5GKT5_TUBMMLactamase_B domain-containing protein. (747 aa)
D5GLJ2_TUBMMHistone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (412 aa)
D5GM32_TUBMMTelo_bind domain-containing protein. (586 aa)
D5GMT4_TUBMMSANT domain-containing protein. (557 aa)
D5GMZ3_TUBMMTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (832 aa)
Your Current Organism:
Tuber melanosporum
NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28
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