(32 nodes) Response to topologically incorrect protein network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G8L3_TUBMM	Uncharacterized protein. (831 aa)
	D5G8L0_TUBMM	Ubiquitin carboxyl-terminal hydrolase. (313 aa)
	D5G835_TUBMM	Uncharacterized protein. (753 aa)
	D5G6W7_TUBMM	Uncharacterized protein. (81 aa)
	D5G6G1_TUBMM	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (306 aa)
	D5G5U0_TUBMM	PRKCSH domain-containing protein. (375 aa)
	D5G588_TUBMM	Uncharacterized protein; Belongs to the ClpA/ClpB family. (836 aa)
	D5G4R8_TUBMM	bVLRF1 domain-containing protein. (612 aa)
	D5G409_TUBMM	Uncharacterized protein; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins. (295 aa)
	D5GPQ9_TUBMM	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (438 aa)
	D5GPJ7_TUBMM	Uncharacterized protein. (178 aa)
	D5GPI6_TUBMM	Uncharacterized protein. (449 aa)
	D5GP75_TUBMM	Uncharacterized protein. (251 aa)
	D5GNL1_TUBMM	Uncharacterized protein; Belongs to the heat shock protein 70 family. (619 aa)
	D5GMY7_TUBMM	Uncharacterized protein. (1223 aa)
	D5GM11_TUBMM	Uncharacterized protein; Belongs to the heat shock protein 70 family. (656 aa)
	D5GLQ5_TUBMM	Protein kinase domain-containing protein. (620 aa)
	D5GLE5_TUBMM	Uncharacterized protein; Belongs to the AAA ATPase family. (818 aa)
	D5GK37_TUBMM	Uncharacterized protein. (367 aa)
	D5GJ02_TUBMM	RING-type domain-containing protein. (642 aa)
	D5GIA2_TUBMM	BAG domain-containing protein. (266 aa)
	D5GHW7_TUBMM	Uncharacterized protein. (639 aa)
	D5GGR2_TUBMM	Uncharacterized protein. (521 aa)
	D5GE36_TUBMM	Ubiquitin-like domain-containing protein. (650 aa)
	D5GDU7_TUBMM	OTU domain-containing protein. (326 aa)
	D5GC42_TUBMM	Uncharacterized protein. (256 aa)
	D5GBR9_TUBMM	Uncharacterized protein. (404 aa)
	D5GB84_TUBMM	Uncharacterized protein. (350 aa)
	D5GB81_TUBMM	Uncharacterized protein. (1504 aa)
	D5G9D3_TUBMM	Uncharacterized protein. (605 aa)
	D5G924_TUBMM	J domain-containing protein. (359 aa)
	D5G8Y7_TUBMM	Uncharacterized protein; Belongs to the BI1 family. (274 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G4R8_TUBMM	D5G835_TUBMM	D5G4R8	D5G835	bVLRF1 domain-containing protein.	Uncharacterized protein.	0.416
D5G4R8_TUBMM	D5GK37_TUBMM	D5G4R8	D5GK37	bVLRF1 domain-containing protein.	Uncharacterized protein.	0.617
D5G4R8_TUBMM	D5GLE5_TUBMM	D5G4R8	D5GLE5	bVLRF1 domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.896
D5G588_TUBMM	D5G6W7_TUBMM	D5G588	D5G6W7	Uncharacterized protein; Belongs to the ClpA/ClpB family.	Uncharacterized protein.	0.665
D5G588_TUBMM	D5G8L3_TUBMM	D5G588	D5G8L3	Uncharacterized protein; Belongs to the ClpA/ClpB family.	Uncharacterized protein.	0.607
D5G588_TUBMM	D5G924_TUBMM	D5G588	D5G924	Uncharacterized protein; Belongs to the ClpA/ClpB family.	J domain-containing protein.	0.492
D5G588_TUBMM	D5GBR9_TUBMM	D5G588	D5GBR9	Uncharacterized protein; Belongs to the ClpA/ClpB family.	Uncharacterized protein.	0.493
D5G588_TUBMM	D5GGR2_TUBMM	D5G588	D5GGR2	Uncharacterized protein; Belongs to the ClpA/ClpB family.	Uncharacterized protein.	0.475
D5G588_TUBMM	D5GM11_TUBMM	D5G588	D5GM11	Uncharacterized protein; Belongs to the ClpA/ClpB family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.620
D5G588_TUBMM	D5GNL1_TUBMM	D5G588	D5GNL1	Uncharacterized protein; Belongs to the ClpA/ClpB family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.665
D5G588_TUBMM	D5GPQ9_TUBMM	D5G588	D5GPQ9	Uncharacterized protein; Belongs to the ClpA/ClpB family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.556
D5G5U0_TUBMM	D5G6G1_TUBMM	D5G5U0	D5G6G1	PRKCSH domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.991
D5G5U0_TUBMM	D5G835_TUBMM	D5G5U0	D5G835	PRKCSH domain-containing protein.	Uncharacterized protein.	0.408
D5G5U0_TUBMM	D5G8L3_TUBMM	D5G5U0	D5G8L3	PRKCSH domain-containing protein.	Uncharacterized protein.	0.545
D5G5U0_TUBMM	D5GB81_TUBMM	D5G5U0	D5GB81	PRKCSH domain-containing protein.	Uncharacterized protein.	0.658
D5G5U0_TUBMM	D5GGR2_TUBMM	D5G5U0	D5GGR2	PRKCSH domain-containing protein.	Uncharacterized protein.	0.468
D5G5U0_TUBMM	D5GK37_TUBMM	D5G5U0	D5GK37	PRKCSH domain-containing protein.	Uncharacterized protein.	0.535
D5G5U0_TUBMM	D5GLE5_TUBMM	D5G5U0	D5GLE5	PRKCSH domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.991
D5G5U0_TUBMM	D5GM11_TUBMM	D5G5U0	D5GM11	PRKCSH domain-containing protein.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.795
D5G6G1_TUBMM	D5G5U0_TUBMM	D5G6G1	D5G5U0	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	PRKCSH domain-containing protein.	0.991