(10 nodes) DNA replication, removal of RNA primer network (Tuber melanosporum)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	D5GHF2_TUBMM	Uncharacterized protein. (178 aa)
	D5GJX0_TUBMM	Uncharacterized protein. (361 aa)
	D5GGI0_TUBMM	RNase H domain-containing protein. (405 aa)
	D5GL19_TUBMM	Uncharacterized protein. (114 aa)
	D5GPK3_TUBMM	RNase H domain-containing protein. (370 aa)
	D5GJA0_TUBMM	Uncharacterized protein. (430 aa)
	D5GK70_TUBMM	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (336 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (481 aa)
	D5G7G1_TUBMM	RNase H domain-containing protein. (782 aa)
	D5G8A5_TUBMM	Uncharacterized protein. (413 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G7G1_TUBMM	D5GK70_TUBMM	D5G7G1	D5GK70	RNase H domain-containing protein.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.653
D5G8A5_TUBMM	D5GJA0_TUBMM	D5G8A5	D5GJA0	Uncharacterized protein.	Uncharacterized protein.	0.993
D5G8A5_TUBMM	D5GJX0_TUBMM	D5G8A5	D5GJX0	Uncharacterized protein.	Uncharacterized protein.	0.900
D5G8A5_TUBMM	FEN1	D5G8A5	D5G565	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.576
D5GGI0_TUBMM	D5GK70_TUBMM	D5GGI0	D5GK70	RNase H domain-containing protein.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.653
D5GHF2_TUBMM	D5GK70_TUBMM	D5GHF2	D5GK70	Uncharacterized protein.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.586
D5GJA0_TUBMM	D5G8A5_TUBMM	D5GJA0	D5G8A5	Uncharacterized protein.	Uncharacterized protein.	0.993
D5GJA0_TUBMM	D5GJX0_TUBMM	D5GJA0	D5GJX0	Uncharacterized protein.	Uncharacterized protein.	0.993
D5GJA0_TUBMM	D5GK70_TUBMM	D5GJA0	D5GK70	Uncharacterized protein.	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.777
D5GJA0_TUBMM	FEN1	D5GJA0	D5G565	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.963
D5GJX0_TUBMM	D5G8A5_TUBMM	D5GJX0	D5G8A5	Uncharacterized protein.	Uncharacterized protein.	0.900
D5GJX0_TUBMM	D5GJA0_TUBMM	D5GJX0	D5GJA0	Uncharacterized protein.	Uncharacterized protein.	0.993
D5GJX0_TUBMM	FEN1	D5GJX0	D5G565	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.576
D5GK70_TUBMM	D5G7G1_TUBMM	D5GK70	D5G7G1	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	RNase H domain-containing protein.	0.653
D5GK70_TUBMM	D5GGI0_TUBMM	D5GK70	D5GGI0	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	RNase H domain-containing protein.	0.653
D5GK70_TUBMM	D5GHF2_TUBMM	D5GK70	D5GHF2	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Uncharacterized protein.	0.586
D5GK70_TUBMM	D5GJA0_TUBMM	D5GK70	D5GJA0	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Uncharacterized protein.	0.777
D5GK70_TUBMM	D5GL19_TUBMM	D5GK70	D5GL19	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Uncharacterized protein.	0.586
D5GK70_TUBMM	D5GPK3_TUBMM	D5GK70	D5GPK3	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	RNase H domain-containing protein.	0.653
D5GK70_TUBMM	FEN1	D5GK70	D5G565	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.691