(13 nodes) Mitotic DNA integrity checkpoint signaling network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G513_TUBMM	Uncharacterized protein. (519 aa)
	D5GNP2_TUBMM	Uncharacterized protein. (1044 aa)
	D5GPI5_TUBMM	HORMA domain-containing protein. (216 aa)
	D5GPI9_TUBMM	MRC1 domain-containing protein. (1224 aa)
	D5GFK8_TUBMM	Uncharacterized protein. (264 aa)
	D5GH36_TUBMM	Uncharacterized protein. (866 aa)
	D5GE30_TUBMM	ERCC4 domain-containing protein. (748 aa)
	D5GD77_TUBMM	Checkpoint protein; Belongs to the HUS1 family. (287 aa)
	D5G670_TUBMM	Protein kinase domain-containing protein. (525 aa)
	D5G5G2_TUBMM	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (769 aa)
	D5G553_TUBMM	Protein kinase domain-containing protein. (558 aa)
	D5GMT3_TUBMM	ERCC4 domain-containing protein. (317 aa)
	D5GM69_TUBMM	Uncharacterized protein. (874 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G513_TUBMM	D5G553_TUBMM	D5G513	D5G553	Uncharacterized protein.	Protein kinase domain-containing protein.	0.406
D5G513_TUBMM	D5G5G2_TUBMM	D5G513	D5G5G2	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.742
D5G513_TUBMM	D5G670_TUBMM	D5G513	D5G670	Uncharacterized protein.	Protein kinase domain-containing protein.	0.832
D5G513_TUBMM	D5GD77_TUBMM	D5G513	D5GD77	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.999
D5G513_TUBMM	D5GE30_TUBMM	D5G513	D5GE30	Uncharacterized protein.	ERCC4 domain-containing protein.	0.484
D5G513_TUBMM	D5GH36_TUBMM	D5G513	D5GH36	Uncharacterized protein.	Uncharacterized protein.	0.988
D5G513_TUBMM	D5GM69_TUBMM	D5G513	D5GM69	Uncharacterized protein.	Uncharacterized protein.	0.996
D5G513_TUBMM	D5GNP2_TUBMM	D5G513	D5GNP2	Uncharacterized protein.	Uncharacterized protein.	0.690
D5G513_TUBMM	D5GPI9_TUBMM	D5G513	D5GPI9	Uncharacterized protein.	MRC1 domain-containing protein.	0.671
D5G553_TUBMM	D5G513_TUBMM	D5G553	D5G513	Protein kinase domain-containing protein.	Uncharacterized protein.	0.406
D5G553_TUBMM	D5G670_TUBMM	D5G553	D5G670	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.769
D5G553_TUBMM	D5GH36_TUBMM	D5G553	D5GH36	Protein kinase domain-containing protein.	Uncharacterized protein.	0.692
D5G553_TUBMM	D5GNP2_TUBMM	D5G553	D5GNP2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.993
D5G553_TUBMM	D5GPI5_TUBMM	D5G553	D5GPI5	Protein kinase domain-containing protein.	HORMA domain-containing protein.	0.416
D5G553_TUBMM	D5GPI9_TUBMM	D5G553	D5GPI9	Protein kinase domain-containing protein.	MRC1 domain-containing protein.	0.724
D5G5G2_TUBMM	D5G513_TUBMM	D5G5G2	D5G513	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.742
D5G5G2_TUBMM	D5G670_TUBMM	D5G5G2	D5G670	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Protein kinase domain-containing protein.	0.689
D5G5G2_TUBMM	D5GD77_TUBMM	D5G5G2	D5GD77	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Checkpoint protein; Belongs to the HUS1 family.	0.801
D5G5G2_TUBMM	D5GE30_TUBMM	D5G5G2	D5GE30	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	ERCC4 domain-containing protein.	0.773
D5G5G2_TUBMM	D5GH36_TUBMM	D5G5G2	D5GH36	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.699