(20 nodes) Ribosomal protein S5 domain 2-type fold, subgroup network (Tuber melanosporum)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	D5GF28_TUBMM	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1612 aa)
	D5GER4_TUBMM	Uncharacterized protein. (465 aa)
	MEF1	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. (773 aa)
	D5GAX2_TUBMM	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (261 aa)
	D5GAE7_TUBMM	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (390 aa)
	D5G952_TUBMM	DNA_mis_repair domain-containing protein. (693 aa)
	MEF2	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (747 aa)
	D5G8V5_TUBMM	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (376 aa)
	D5G6P1_TUBMM	Uncharacterized protein. (1023 aa)
	PIM1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1073 aa)
	D5G5P5_TUBMM	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (442 aa)
	D5G4Z5_TUBMM	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (144 aa)
	D5G3U9_TUBMM	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (335 aa)
	D5GNC5_TUBMM	Tr-type G domain-containing protein. (979 aa)
	D5GL71_TUBMM	Lon protease homolog; Belongs to the peptidase S16 family. (888 aa)
	D5GIV1_TUBMM	GHMP_kinases_N domain-containing protein. (366 aa)
	D5GIC7_TUBMM	DNA_mis_repair domain-containing protein. (608 aa)
	D5GI42_TUBMM	Uncharacterized protein. (506 aa)
	D5GHR1_TUBMM	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (425 aa)
	D5GH11_TUBMM	Tr-type G domain-containing protein. (897 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G3U9_TUBMM	D5G4Z5_TUBMM	D5G3U9	D5G4Z5	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.917
D5G3U9_TUBMM	D5G8V5_TUBMM	D5G3U9	D5G8V5	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.999
D5G3U9_TUBMM	D5GER4_TUBMM	D5G3U9	D5GER4	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Uncharacterized protein.	0.779
D5G3U9_TUBMM	D5GF28_TUBMM	D5G3U9	D5GF28	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.433
D5G3U9_TUBMM	D5GH11_TUBMM	D5G3U9	D5GH11	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Tr-type G domain-containing protein.	0.779
D5G3U9_TUBMM	D5GNC5_TUBMM	D5G3U9	D5GNC5	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Tr-type G domain-containing protein.	0.779
D5G3U9_TUBMM	MEF1	D5G3U9	D5GBE7	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	0.788
D5G4Z5_TUBMM	D5G3U9_TUBMM	D5G4Z5	D5G3U9	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.917
D5G4Z5_TUBMM	D5G8V5_TUBMM	D5G4Z5	D5G8V5	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.958
D5G4Z5_TUBMM	D5GAX2_TUBMM	D5G4Z5	D5GAX2	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.999
D5G4Z5_TUBMM	D5GER4_TUBMM	D5G4Z5	D5GER4	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Uncharacterized protein.	0.954
D5G4Z5_TUBMM	D5GH11_TUBMM	D5G4Z5	D5GH11	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Tr-type G domain-containing protein.	0.705
D5G4Z5_TUBMM	D5GNC5_TUBMM	D5G4Z5	D5GNC5	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Tr-type G domain-containing protein.	0.722
D5G4Z5_TUBMM	MEF1	D5G4Z5	D5GBE7	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.	0.705
D5G4Z5_TUBMM	MEF2	D5G4Z5	D5G8X3	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.629
D5G5P5_TUBMM	D5GAE7_TUBMM	D5G5P5	D5GAE7	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.	0.993
D5G5P5_TUBMM	D5GHR1_TUBMM	D5G5P5	D5GHR1	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	0.986
D5G5P5_TUBMM	D5GI42_TUBMM	D5G5P5	D5GI42	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	Uncharacterized protein.	0.617
D5G5P5_TUBMM	D5GIV1_TUBMM	D5G5P5	D5GIV1	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.	GHMP_kinases_N domain-containing protein.	0.618
D5G6P1_TUBMM	D5G952_TUBMM	D5G6P1	D5G952	Uncharacterized protein.	DNA_mis_repair domain-containing protein.	0.999