STRINGSTRING
D5G561_TUBMM D5G561_TUBMM D5G562_TUBMM D5G562_TUBMM D5G566_TUBMM D5G566_TUBMM D5G8P1_TUBMM D5G8P1_TUBMM D5GBC0_TUBMM D5GBC0_TUBMM D5GCV3_TUBMM D5GCV3_TUBMM D5GDB9_TUBMM D5GDB9_TUBMM D5GF07_TUBMM D5GF07_TUBMM D5GK31_TUBMM D5GK31_TUBMM D5GKI6_TUBMM D5GKI6_TUBMM D5GMZ3_TUBMM D5GMZ3_TUBMM D5GN86_TUBMM D5GN86_TUBMM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D5G561_TUBMMHistone H2A; Belongs to the histone H2A family. (134 aa)
D5G562_TUBMMHistone H2B; Belongs to the histone H2B family. (138 aa)
D5G566_TUBMMH15 domain-containing protein. (228 aa)
D5G8P1_TUBMMCENP-T_C domain-containing protein. (532 aa)
D5GBC0_TUBMMHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
D5GCV3_TUBMMHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (143 aa)
D5GDB9_TUBMMHistone domain-containing protein. (152 aa)
D5GF07_TUBMMHistone domain-containing protein. (136 aa)
D5GK31_TUBMMHistone H2A; Belongs to the histone H2A family. (123 aa)
D5GKI6_TUBMMHistone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1200 aa)
D5GMZ3_TUBMMTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (832 aa)
D5GN86_TUBMMFACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (570 aa)
Your Current Organism:
Tuber melanosporum
NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28
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