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MED18 | Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (248 aa) | ||||
MED5 | Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1005 aa) | ||||
D5G578_TUBMM | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (229 aa) | ||||
D5G586_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (806 aa) | ||||
D5G5H7_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (998 aa) | ||||
D5G5I2_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (906 aa) | ||||
D5G612_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (923 aa) | ||||
D5G646_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (756 aa) | ||||
MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (608 aa) | ||||
D5G6V1_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (917 aa) | ||||
D5G6Y5_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (860 aa) | ||||
D5G7D7_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (648 aa) | ||||
D5G7D8_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (804 aa) | ||||
D5G7L9_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (639 aa) | ||||
D5G8D4_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (925 aa) | ||||
D5G8D7_TUBMM | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (544 aa) | ||||
D5G8E2_TUBMM | Fork-head domain-containing protein. (358 aa) | ||||
D5G8G1_TUBMM | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (229 aa) | ||||
D5G997_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (712 aa) | ||||
D5G9H5_TUBMM | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (111 aa) | ||||
D5GA76_TUBMM | Enhancer of polycomb-like protein. (604 aa) | ||||
KAE1 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (349 aa) | ||||
D5GA97_TUBMM | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (571 aa) | ||||
D5GAN6_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (885 aa) | ||||
D5GAS5_TUBMM | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (643 aa) | ||||
D5GAZ6_TUBMM | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (474 aa) | ||||
D5GB06_TUBMM | Repressor of RNA polymerase III transcription MAF1; Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family. (276 aa) | ||||
D5GB61_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (877 aa) | ||||
D5GBE2_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (748 aa) | ||||
D5GBL8_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (824 aa) | ||||
D5GBW8_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (655 aa) | ||||
D5GC28_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (871 aa) | ||||
D5GC74_TUBMM | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (258 aa) | ||||
D5GCC4_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (794 aa) | ||||
D5GCF3_TUBMM | Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (118 aa) | ||||
D5GCI7_TUBMM | Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (166 aa) | ||||
D5GCT6_TUBMM | Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (122 aa) | ||||
D5GD20_TUBMM | Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1419 aa) | ||||
MED6 | Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (320 aa) | ||||
D5GDE9_TUBMM | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (228 aa) | ||||
D5GDH3_TUBMM | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (218 aa) | ||||
D5GDT0_TUBMM | ARID domain-containing protein. (1001 aa) | ||||
D5GEA1_TUBMM | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (114 aa) | ||||
D5GEV5_TUBMM | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (115 aa) | ||||
D5GEX9_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (1125 aa) | ||||
MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (260 aa) | ||||
D5GF95_TUBMM | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (930 aa) | ||||
D5GFV7_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (639 aa) | ||||
D5GG12_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (778 aa) | ||||
D5GG51_TUBMM | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (378 aa) | ||||
D5GGF2_TUBMM | Uncharacterized protein. (1340 aa) | ||||
D5GGJ8_TUBMM | RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa) | ||||
MED10 | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (152 aa) | ||||
D5GHA6_TUBMM | Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (377 aa) | ||||
D5GHD4_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (622 aa) | ||||
MED11 | Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (139 aa) | ||||
D5GHR5_TUBMM | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (516 aa) | ||||
MED9 | Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (115 aa) | ||||
D5GIQ1_TUBMM | Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (203 aa) | ||||
D5GIW5_TUBMM | MADS-box domain-containing protein. (563 aa) | ||||
D5GIY4_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (856 aa) | ||||
D5GJD1_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (442 aa) | ||||
MED8 | Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (282 aa) | ||||
D5GJJ3_TUBMM | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa) | ||||
D5GJP9_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (842 aa) | ||||
D5GJR0_TUBMM | Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (525 aa) | ||||
D5GJU9_TUBMM | Uncharacterized protein. (431 aa) | ||||
MED19 | Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (351 aa) | ||||
D5GK09_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (789 aa) | ||||
D5GK82_TUBMM | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (469 aa) | ||||
D5GKK1_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (1057 aa) | ||||
D5GKM4_TUBMM | RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (460 aa) | ||||
D5GKX1_TUBMM | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (303 aa) | ||||
D5GKZ6_TUBMM | Uncharacterized protein. (329 aa) | ||||
D5GL92_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (885 aa) | ||||
SUS1 | Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (94 aa) | ||||
D5GM19_TUBMM | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1195 aa) | ||||
D5GM48_TUBMM | Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1054 aa) | ||||
D5GM88_TUBMM | Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (724 aa) | ||||
D5GMS0_TUBMM | Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (928 aa) | ||||
D5GMU5_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (663 aa) | ||||
D5GN86_TUBMM | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (570 aa) | ||||
D5GND9_TUBMM | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1416 aa) | ||||
D5GNE3_TUBMM | Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (762 aa) | ||||
D5GNP0_TUBMM | Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (285 aa) | ||||
D5GQ49_TUBMM | MADS-box domain-containing protein. (248 aa) | ||||
D5GQ67_TUBMM | Nascent polypeptide-associated complex subunit beta. (184 aa) | ||||
D5GQ83_TUBMM | Zn(2)-C6 fungal-type domain-containing protein. (931 aa) |