(44 nodes) Disease network (Tuber melanosporum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	D5G400_TUBMM	Thioredoxin domain-containing protein. (332 aa)
	D5GPW2_TUBMM	Protein kinase domain-containing protein. (613 aa)
	D5GPH3_TUBMM	LMWPc domain-containing protein. (178 aa)
	D5GNE4_TUBMM	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (647 aa)
	D5GND3_TUBMM	Uncharacterized protein. (475 aa)
	D5GN87_TUBMM	Uncharacterized protein. (715 aa)
	D5GN41_TUBMM	Lactamase_B domain-containing protein. (480 aa)
	D5GM45_TUBMM	Uncharacterized protein. (802 aa)
	D5GLL3_TUBMM	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (151 aa)
	D5GLK7_TUBMM	Coronin; Belongs to the WD repeat coronin family. (582 aa)
	D5GL31_TUBMM	Uncharacterized protein. (351 aa)
	D5GI86_TUBMM	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (1065 aa)
	D5GI08_TUBMM	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (508 aa)
	D5GH58_TUBMM	CNH domain-containing protein. (971 aa)
	D5GGY3_TUBMM	Tr-type G domain-containing protein. (121 aa)
	D5GGY2_TUBMM	Tr-type G domain-containing protein. (303 aa)
	D5GGT2_TUBMM	Uncharacterized protein. (1097 aa)
	D5GG24_TUBMM	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (619 aa)
	D5GFQ8_TUBMM	Uncharacterized protein. (266 aa)
	D5GFQ7_TUBMM	Importin N-terminal domain-containing protein. (842 aa)
	D5GEB6_TUBMM	Glyco_hydro_63 domain-containing protein. (1014 aa)
	D5GE27_TUBMM	E3 ubiquitin-protein ligase PEP5. (961 aa)
	D5GDR5_TUBMM	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (671 aa)
	D5GDD9_TUBMM	Uncharacterized protein. (273 aa)
	D5GD92_TUBMM	Uncharacterized protein. (847 aa)
	D5GD76_TUBMM	Pep3_Vps18 domain-containing protein. (878 aa)
	D5GCS5_TUBMM	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (730 aa)
	D5GBR1_TUBMM	Uncharacterized protein. (816 aa)
	D5GBF9_TUBMM	PH domain-containing protein. (1142 aa)
	D5GAY9_TUBMM	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (832 aa)
	D5GAW8_TUBMM	CNH domain-containing protein. (1186 aa)
	D5G9I5_TUBMM	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (947 aa)
	D5G9F6_TUBMM	HTH La-type RNA-binding domain-containing protein. (1104 aa)
	D5G977_TUBMM	Uncharacterized protein. (474 aa)
	D5G8D5_TUBMM	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (483 aa)
	D5G841_TUBMM	Uncharacterized protein. (212 aa)
	D5G7R4_TUBMM	Uncharacterized protein. (511 aa)
	D5G7C2_TUBMM	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (300 aa)
	D5G757_TUBMM	Uncharacterized protein. (328 aa)
	D5G719_TUBMM	UBIQUITIN_CONJUGAT_2 domain-containing protein. (1201 aa)
	D5G6S5_TUBMM	Uncharacterized protein. (183 aa)
	D5G6E7_TUBMM	Uncharacterized protein. (197 aa)
	D5G4P7_TUBMM	Uncharacterized protein. (880 aa)
	D5G4K6_TUBMM	Uncharacterized protein; Belongs to the glycosyl hydrolase 28 family. (496 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G4P7_TUBMM	D5G9I5_TUBMM	D5G4P7	D5G9I5	Uncharacterized protein.	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.644
D5G6S5_TUBMM	D5G7R4_TUBMM	D5G6S5	D5G7R4	Uncharacterized protein.	Uncharacterized protein.	0.560
D5G6S5_TUBMM	D5GM45_TUBMM	D5G6S5	D5GM45	Uncharacterized protein.	Uncharacterized protein.	0.560
D5G719_TUBMM	D5GLL3_TUBMM	D5G719	D5GLL3	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.618
D5G7C2_TUBMM	D5G8D5_TUBMM	D5G7C2	D5G8D5	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.999
D5G7C2_TUBMM	D5G977_TUBMM	D5G7C2	D5G977	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.527
D5G7C2_TUBMM	D5G9I5_TUBMM	D5G7C2	D5G9I5	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.419
D5G7C2_TUBMM	D5GD92_TUBMM	D5G7C2	D5GD92	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.915
D5G7C2_TUBMM	D5GLL3_TUBMM	D5G7C2	D5GLL3	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.999
D5G7C2_TUBMM	D5GN87_TUBMM	D5G7C2	D5GN87	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.999
D5G7R4_TUBMM	D5G6S5_TUBMM	D5G7R4	D5G6S5	Uncharacterized protein.	Uncharacterized protein.	0.560
D5G7R4_TUBMM	D5GM45_TUBMM	D5G7R4	D5GM45	Uncharacterized protein.	Uncharacterized protein.	0.921
D5G8D5_TUBMM	D5G7C2_TUBMM	D5G8D5	D5G7C2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.999
D5G8D5_TUBMM	D5G9I5_TUBMM	D5G8D5	D5G9I5	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.495
D5G8D5_TUBMM	D5GD92_TUBMM	D5G8D5	D5GD92	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.945
D5G8D5_TUBMM	D5GEB6_TUBMM	D5G8D5	D5GEB6	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Glyco_hydro_63 domain-containing protein.	0.419
D5G8D5_TUBMM	D5GLL3_TUBMM	D5G8D5	D5GLL3	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	0.999
D5G8D5_TUBMM	D5GN87_TUBMM	D5G8D5	D5GN87	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	Uncharacterized protein.	0.999
D5G977_TUBMM	D5G7C2_TUBMM	D5G977	D5G7C2	Uncharacterized protein.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.527
D5G977_TUBMM	D5GBR1_TUBMM	D5G977	D5GBR1	Uncharacterized protein.	Uncharacterized protein.	0.645