(23 nodes) Chromosome Maintenance network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5GKM8_TUBMM	Uncharacterized protein. (292 aa)
	D5G4C3_TUBMM	Uncharacterized protein. (898 aa)
	D5G562_TUBMM	Histone H2B; Belongs to the histone H2B family. (138 aa)
	D5G8A5_TUBMM	Uncharacterized protein. (413 aa)
	D5G8S2_TUBMM	Uncharacterized protein. (96 aa)
	D5GAZ4_TUBMM	3'-5' exonuclease domain-containing protein. (970 aa)
	D5GAZ6_TUBMM	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (474 aa)
	D5GBQ9_TUBMM	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (614 aa)
	D5GDH9_TUBMM	Uncharacterized protein. (1069 aa)
	D5GDK2_TUBMM	Uncharacterized protein. (145 aa)
	D5GEI4_TUBMM	Uncharacterized protein. (1100 aa)
	D5GFC0_TUBMM	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (527 aa)
	D5GGJ8_TUBMM	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (458 aa)
	D5GHA1_TUBMM	TruB_N domain-containing protein. (210 aa)
	D5GHA2_TUBMM	TruB_C_2 domain-containing protein. (196 aa)
	D5GHI0_TUBMM	HD domain-containing protein. (214 aa)
	D5GHW9_TUBMM	AAA domain-containing protein. (779 aa)
	D5GJN4_TUBMM	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (214 aa)
	D5GJX0_TUBMM	Uncharacterized protein. (361 aa)
	D5GKS1_TUBMM	PUA domain-containing protein. (464 aa)
	D5GM32_TUBMM	Telo_bind domain-containing protein. (586 aa)
	D5GMZ3_TUBMM	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (832 aa)
	D5GN76_TUBMM	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (253 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G4C3_TUBMM	D5G8A5_TUBMM	D5G4C3	D5G8A5	Uncharacterized protein.	Uncharacterized protein.	0.487
D5G4C3_TUBMM	D5GAZ4_TUBMM	D5G4C3	D5GAZ4	Uncharacterized protein.	3'-5' exonuclease domain-containing protein.	0.410
D5G4C3_TUBMM	D5GBQ9_TUBMM	D5G4C3	D5GBQ9	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.937
D5G4C3_TUBMM	D5GHI0_TUBMM	D5G4C3	D5GHI0	Uncharacterized protein.	HD domain-containing protein.	0.578
D5G4C3_TUBMM	D5GHW9_TUBMM	D5G4C3	D5GHW9	Uncharacterized protein.	AAA domain-containing protein.	0.587
D5G4C3_TUBMM	D5GJX0_TUBMM	D5G4C3	D5GJX0	Uncharacterized protein.	Uncharacterized protein.	0.487
D5G4C3_TUBMM	D5GM32_TUBMM	D5G4C3	D5GM32	Uncharacterized protein.	Telo_bind domain-containing protein.	0.468
D5G4C3_TUBMM	D5GMZ3_TUBMM	D5G4C3	D5GMZ3	Uncharacterized protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.417
D5G562_TUBMM	D5GAZ6_TUBMM	D5G562	D5GAZ6	Histone H2B; Belongs to the histone H2B family.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.892
D5G562_TUBMM	D5GDH9_TUBMM	D5G562	D5GDH9	Histone H2B; Belongs to the histone H2B family.	Uncharacterized protein.	0.937
D5G562_TUBMM	D5GEI4_TUBMM	D5G562	D5GEI4	Histone H2B; Belongs to the histone H2B family.	Uncharacterized protein.	0.542
D5G562_TUBMM	D5GGJ8_TUBMM	D5G562	D5GGJ8	Histone H2B; Belongs to the histone H2B family.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.915
D5G562_TUBMM	D5GM32_TUBMM	D5G562	D5GM32	Histone H2B; Belongs to the histone H2B family.	Telo_bind domain-containing protein.	0.429
D5G8A5_TUBMM	D5G4C3_TUBMM	D5G8A5	D5G4C3	Uncharacterized protein.	Uncharacterized protein.	0.487
D5G8A5_TUBMM	D5GAZ4_TUBMM	D5G8A5	D5GAZ4	Uncharacterized protein.	3'-5' exonuclease domain-containing protein.	0.412
D5G8A5_TUBMM	D5GBQ9_TUBMM	D5G8A5	D5GBQ9	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.570
D5G8A5_TUBMM	D5GFC0_TUBMM	D5G8A5	D5GFC0	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.487
D5G8A5_TUBMM	D5GJX0_TUBMM	D5G8A5	D5GJX0	Uncharacterized protein.	Uncharacterized protein.	0.900
D5G8S2_TUBMM	D5GAZ6_TUBMM	D5G8S2	D5GAZ6	Uncharacterized protein.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.630
D5G8S2_TUBMM	D5GGJ8_TUBMM	D5G8S2	D5GGJ8	Uncharacterized protein.	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.	0.630