(42 nodes) Glycerophospholipid metabolism network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G443_TUBMM	CTP_transf_like domain-containing protein. (463 aa)
	D5G4I1_TUBMM	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (491 aa)
	D5G5B3_TUBMM	Uncharacterized protein. (251 aa)
	D5G6A2_TUBMM	LNS2 domain-containing protein. (783 aa)
	D5G7D6_TUBMM	CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (232 aa)
	D5G7Z1_TUBMM	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (405 aa)
	D5G8L4_TUBMM	Choline_kin_N domain-containing protein. (673 aa)
	D5G9A1_TUBMM	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (588 aa)
	D5GA05_TUBMM	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC). (208 aa)
	D5GAC0_TUBMM	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (529 aa)
	D5GAK6_TUBMM	Phospholipase. (1428 aa)
	D5GB42_TUBMM	GP-PDE domain-containing protein. (254 aa)
	D5GBH3_TUBMM	Uncharacterized protein. (316 aa)
	D5GC21_TUBMM	Phospholipase. (1062 aa)
	D5GC75_TUBMM	acidPPc domain-containing protein. (258 aa)
	D5GCE1_TUBMM	PlsC domain-containing protein. (747 aa)
	D5GCG1_TUBMM	Lysophospholipase. (822 aa)
	D5GD00_TUBMM	Uncharacterized protein. (653 aa)
	D5GD55_TUBMM	CTP_transf_like domain-containing protein. (392 aa)
	D5GDD8_TUBMM	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family. (542 aa)
	D5GDQ6_TUBMM	CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (237 aa)
	D5GE57_TUBMM	Uncharacterized protein. (151 aa)
	PSD1	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (385 aa)
	D5GG28_TUBMM	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (462 aa)
	D5GHB7_TUBMM	Uncharacterized protein. (206 aa)
	D5GHK5_TUBMM	Uncharacterized protein. (413 aa)
	D5GHX4_TUBMM	AB hydrolase-1 domain-containing protein. (520 aa)
	D5GJ67_TUBMM	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (427 aa)
	D5GJD2_TUBMM	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family. (758 aa)
	D5GJD8_TUBMM	acidPPc domain-containing protein. (293 aa)
	D5GJE4_TUBMM	Lysophospholipase. (544 aa)
	D5GJF2_TUBMM	Uncharacterized protein. (809 aa)
	D5GKD5_TUBMM	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (277 aa)
	D5GL74_TUBMM	Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family. (945 aa)
	D5GLB7_TUBMM	PSDC domain-containing protein. (407 aa)
	D5GLL0_TUBMM	PlsC domain-containing protein. (340 aa)
	D5GLL1_TUBMM	Tafazzin family protein; Belongs to the taffazin family. (329 aa)
	D5GLN9_TUBMM	Uncharacterized protein. (323 aa)
	D5GLS2_TUBMM	CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (231 aa)
	D5GLX0_TUBMM	acidPPc domain-containing protein. (488 aa)
	D5GMX7_TUBMM	Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. (1422 aa)
	PSD2	Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1090 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G443_TUBMM	D5G6A2_TUBMM	D5G443	D5G6A2	CTP_transf_like domain-containing protein.	LNS2 domain-containing protein.	0.508
D5G443_TUBMM	D5G7Z1_TUBMM	D5G443	D5G7Z1	CTP_transf_like domain-containing protein.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.785
D5G443_TUBMM	D5G8L4_TUBMM	D5G443	D5G8L4	CTP_transf_like domain-containing protein.	Choline_kin_N domain-containing protein.	0.986
D5G443_TUBMM	D5GA05_TUBMM	D5G443	D5GA05	CTP_transf_like domain-containing protein.	Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).	0.551
D5G443_TUBMM	D5GHK5_TUBMM	D5G443	D5GHK5	CTP_transf_like domain-containing protein.	Uncharacterized protein.	0.677
D5G443_TUBMM	D5GJ67_TUBMM	D5G443	D5GJ67	CTP_transf_like domain-containing protein.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.691
D5G443_TUBMM	D5GLN9_TUBMM	D5G443	D5GLN9	CTP_transf_like domain-containing protein.	Uncharacterized protein.	0.564
D5G443_TUBMM	PSD1	D5G443	D5GF41	CTP_transf_like domain-containing protein.	Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.	0.510
D5G4I1_TUBMM	D5G6A2_TUBMM	D5G4I1	D5G6A2	Glycerol-3-phosphate dehydrogenase [NAD(+)].	LNS2 domain-containing protein.	0.816
D5G4I1_TUBMM	D5G9A1_TUBMM	D5G4I1	D5G9A1	Glycerol-3-phosphate dehydrogenase [NAD(+)].	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.	0.988
D5G4I1_TUBMM	D5GB42_TUBMM	D5G4I1	D5GB42	Glycerol-3-phosphate dehydrogenase [NAD(+)].	GP-PDE domain-containing protein.	0.552
D5G4I1_TUBMM	D5GC75_TUBMM	D5G4I1	D5GC75	Glycerol-3-phosphate dehydrogenase [NAD(+)].	acidPPc domain-containing protein.	0.829
D5G4I1_TUBMM	D5GCE1_TUBMM	D5G4I1	D5GCE1	Glycerol-3-phosphate dehydrogenase [NAD(+)].	PlsC domain-containing protein.	0.965
D5G4I1_TUBMM	D5GDD8_TUBMM	D5G4I1	D5GDD8	Glycerol-3-phosphate dehydrogenase [NAD(+)].	Uncharacterized protein; Belongs to the membrane-bound acyltransferase family.	0.825
D5G4I1_TUBMM	D5GJD2_TUBMM	D5G4I1	D5GJD2	Glycerol-3-phosphate dehydrogenase [NAD(+)].	Patatin-like phospholipase domain-containing protein; Lipid hydrolase; Belongs to the PLPL family.	0.809
D5G4I1_TUBMM	D5GJD8_TUBMM	D5G4I1	D5GJD8	Glycerol-3-phosphate dehydrogenase [NAD(+)].	acidPPc domain-containing protein.	0.829
D5G4I1_TUBMM	D5GKD5_TUBMM	D5G4I1	D5GKD5	Glycerol-3-phosphate dehydrogenase [NAD(+)].	1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.	0.946
D5G4I1_TUBMM	D5GLL0_TUBMM	D5G4I1	D5GLL0	Glycerol-3-phosphate dehydrogenase [NAD(+)].	PlsC domain-containing protein.	0.940
D5G4I1_TUBMM	D5GLX0_TUBMM	D5G4I1	D5GLX0	Glycerol-3-phosphate dehydrogenase [NAD(+)].	acidPPc domain-containing protein.	0.829
D5G5B3_TUBMM	D5GCE1_TUBMM	D5G5B3	D5GCE1	Uncharacterized protein.	PlsC domain-containing protein.	0.919