(25 nodes) Pyruvate metabolism network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G5H0_TUBMM	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (496 aa)
	D5G620_TUBMM	Malate dehydrogenase. (347 aa)
	D5G637_TUBMM	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (414 aa)
	D5G745_TUBMM	Uncharacterized protein. (606 aa)
	D5G7G7_TUBMM	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (401 aa)
	D5G8E9_TUBMM	Uncharacterized protein. (593 aa)
	D5G9B7_TUBMM	Uncharacterized protein. (591 aa)
	D5G9P7_TUBMM	FAD-binding PCMH-type domain-containing protein. (577 aa)
	D5G9Y3_TUBMM	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	D5GA85_TUBMM	Malate dehydrogenase. (358 aa)
	D5GAW2_TUBMM	Lactamase_B domain-containing protein. (256 aa)
	D5GEZ1_TUBMM	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
	D5GFM8_TUBMM	Uncharacterized protein. (556 aa)
	D5GGA5_TUBMM	Uncharacterized protein. (481 aa)
	D5GGK4_TUBMM	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (373 aa)
	D5GGN7_TUBMM	Dihydrolipoyl dehydrogenase. (506 aa)
	D5GHC0_TUBMM	Uncharacterized protein. (403 aa)
	D5GHH4_TUBMM	Uncharacterized protein. (416 aa)
	D5GI89_TUBMM	Pyruvate kinase; Belongs to the pyruvate kinase family. (496 aa)
	D5GIF5_TUBMM	Uncharacterized protein; Belongs to the cytochrome b5 family. (499 aa)
	D5GJ82_TUBMM	Pyruvate carboxyltransferase domain-containing protein. (619 aa)
	D5GJS6_TUBMM	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (466 aa)
	D5GLC7_TUBMM	Uncharacterized protein. (280 aa)
	D5GP50_TUBMM	FAD-binding PCMH-type domain-containing protein. (553 aa)
	D5GQ51_TUBMM	Uncharacterized protein. (499 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G5H0_TUBMM	D5G745_TUBMM	D5G5H0	D5G745	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.954
D5G5H0_TUBMM	D5GGA5_TUBMM	D5G5H0	D5GGA5	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.423
D5G5H0_TUBMM	D5GHC0_TUBMM	D5G5H0	D5GHC0	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.429
D5G5H0_TUBMM	D5GIF5_TUBMM	D5G5H0	D5GIF5	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the cytochrome b5 family.	0.423
D5G620_TUBMM	D5G637_TUBMM	D5G620	D5G637	Malate dehydrogenase.	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.428
D5G620_TUBMM	D5G745_TUBMM	D5G620	D5G745	Malate dehydrogenase.	Uncharacterized protein.	0.424
D5G620_TUBMM	D5G7G7_TUBMM	D5G620	D5G7G7	Malate dehydrogenase.	Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.579
D5G620_TUBMM	D5G8E9_TUBMM	D5G620	D5G8E9	Malate dehydrogenase.	Uncharacterized protein.	0.957
D5G620_TUBMM	D5G9B7_TUBMM	D5G620	D5G9B7	Malate dehydrogenase.	Uncharacterized protein.	0.957
D5G620_TUBMM	D5GA85_TUBMM	D5G620	D5GA85	Malate dehydrogenase.	Malate dehydrogenase.	0.903
D5G620_TUBMM	D5GFM8_TUBMM	D5G620	D5GFM8	Malate dehydrogenase.	Uncharacterized protein.	0.936
D5G620_TUBMM	D5GGK4_TUBMM	D5G620	D5GGK4	Malate dehydrogenase.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.636
D5G620_TUBMM	D5GGN7_TUBMM	D5G620	D5GGN7	Malate dehydrogenase.	Dihydrolipoyl dehydrogenase.	0.811
D5G620_TUBMM	D5GHC0_TUBMM	D5G620	D5GHC0	Malate dehydrogenase.	Uncharacterized protein.	0.990
D5G620_TUBMM	D5GHH4_TUBMM	D5G620	D5GHH4	Malate dehydrogenase.	Uncharacterized protein.	0.426
D5G620_TUBMM	D5GI89_TUBMM	D5G620	D5GI89	Malate dehydrogenase.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.845
D5G620_TUBMM	D5GLC7_TUBMM	D5G620	D5GLC7	Malate dehydrogenase.	Uncharacterized protein.	0.449
D5G620_TUBMM	D5GQ51_TUBMM	D5G620	D5GQ51	Malate dehydrogenase.	Uncharacterized protein.	0.982
D5G637_TUBMM	D5G620_TUBMM	D5G637	D5G620	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Malate dehydrogenase.	0.428
D5G637_TUBMM	D5G745_TUBMM	D5G637	D5G745	Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Uncharacterized protein.	0.927