(12 nodes) Butanoate metabolism network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	D5G405_TUBMM	ACT domain-containing protein. (313 aa)
	D5G6G8_TUBMM	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (288 aa)
	D5G7T6_TUBMM	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (449 aa)
	D5G9Y3_TUBMM	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
	D5GBF0_TUBMM	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family. (449 aa)
	D5GDL1_TUBMM	Pyruvate carboxyltransferase domain-containing protein. (331 aa)
	D5GDV4_TUBMM	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (503 aa)
	D5GEZ1_TUBMM	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
	D5GHM7_TUBMM	Uncharacterized protein. (654 aa)
	D5GIH3_TUBMM	Uncharacterized protein. (311 aa)
	D5GK65_TUBMM	Acetolactate synthase. (698 aa)
	D5GKN6_TUBMM	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (479 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G405_TUBMM	D5GDL1_TUBMM	D5G405	D5GDL1	ACT domain-containing protein.	Pyruvate carboxyltransferase domain-containing protein.	0.695
D5G405_TUBMM	D5GK65_TUBMM	D5G405	D5GK65	ACT domain-containing protein.	Acetolactate synthase.	0.999
D5G6G8_TUBMM	D5G9Y3_TUBMM	D5G6G8	D5G9Y3	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.786
D5G6G8_TUBMM	D5GDL1_TUBMM	D5G6G8	D5GDL1	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Pyruvate carboxyltransferase domain-containing protein.	0.625
D5G6G8_TUBMM	D5GDV4_TUBMM	D5G6G8	D5GDV4	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.576
D5G6G8_TUBMM	D5GEZ1_TUBMM	D5G6G8	D5GEZ1	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.767
D5G6G8_TUBMM	D5GHM7_TUBMM	D5G6G8	D5GHM7	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.521
D5G6G8_TUBMM	D5GIH3_TUBMM	D5G6G8	D5GIH3	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein.	0.998
D5G7T6_TUBMM	D5GBF0_TUBMM	D5G7T6	D5GBF0	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family.	0.729
D5G7T6_TUBMM	D5GKN6_TUBMM	D5G7T6	D5GKN6	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.978
D5G9Y3_TUBMM	D5G6G8_TUBMM	D5G9Y3	D5G6G8	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.786
D5G9Y3_TUBMM	D5GDL1_TUBMM	D5G9Y3	D5GDL1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Pyruvate carboxyltransferase domain-containing protein.	0.937
D5G9Y3_TUBMM	D5GDV4_TUBMM	D5G9Y3	D5GDV4	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.966
D5G9Y3_TUBMM	D5GEZ1_TUBMM	D5G9Y3	D5GEZ1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.903
D5G9Y3_TUBMM	D5GHM7_TUBMM	D5G9Y3	D5GHM7	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.958
D5G9Y3_TUBMM	D5GIH3_TUBMM	D5G9Y3	D5GIH3	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.993
D5GBF0_TUBMM	D5G7T6_TUBMM	D5GBF0	D5G7T6	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.729
D5GBF0_TUBMM	D5GHM7_TUBMM	D5GBF0	D5GHM7	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein.	0.618
D5GBF0_TUBMM	D5GKN6_TUBMM	D5GBF0	D5GKN6	Uncharacterized protein; Belongs to the aldehyde dehydrogenase family.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.983
D5GDL1_TUBMM	D5G405_TUBMM	D5GDL1	D5G405	Pyruvate carboxyltransferase domain-containing protein.	ACT domain-containing protein.	0.695