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D5G3X1_TUBMM D5G3X1_TUBMM MCM7 MCM7 FEN1 FEN1 D5G6D9_TUBMM D5G6D9_TUBMM D5G6Y1_TUBMM D5G6Y1_TUBMM D5G6Z1_TUBMM D5G6Z1_TUBMM D5G756_TUBMM D5G756_TUBMM D5G8A5_TUBMM D5G8A5_TUBMM D5G958_TUBMM D5G958_TUBMM D5G962_TUBMM D5G962_TUBMM D5GAV6_TUBMM D5GAV6_TUBMM D5GCG5_TUBMM D5GCG5_TUBMM D5GCR9_TUBMM D5GCR9_TUBMM D5GFI1_TUBMM D5GFI1_TUBMM D5GFV6_TUBMM D5GFV6_TUBMM D5GGI0_TUBMM D5GGI0_TUBMM D5GGS5_TUBMM D5GGS5_TUBMM D5GGS6_TUBMM D5GGS6_TUBMM D5GH17_TUBMM D5GH17_TUBMM D5GH90_TUBMM D5GH90_TUBMM D5GHR5_TUBMM D5GHR5_TUBMM D5GHT0_TUBMM D5GHT0_TUBMM D5GIV2_TUBMM D5GIV2_TUBMM D5GJA0_TUBMM D5GJA0_TUBMM D5GJM1_TUBMM D5GJM1_TUBMM D5GJX0_TUBMM D5GJX0_TUBMM D5GK70_TUBMM D5GK70_TUBMM D5GKW2_TUBMM D5GKW2_TUBMM D5GL82_TUBMM D5GL82_TUBMM D5GLS4_TUBMM D5GLS4_TUBMM D5GLW6_TUBMM D5GLW6_TUBMM D5GM03_TUBMM D5GM03_TUBMM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
D5G3X1_TUBMMDNA helicase; Belongs to the MCM family. (720 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (783 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (481 aa)
D5G6D9_TUBMMDNA polymerase. (1451 aa)
D5G6Y1_TUBMMCBFD_NFYB_HMF domain-containing protein. (124 aa)
D5G6Z1_TUBMMUncharacterized protein. (1003 aa)
D5G756_TUBMMAAA domain-containing protein. (351 aa)
D5G8A5_TUBMMUncharacterized protein. (413 aa)
D5G958_TUBMMRPA_C domain-containing protein. (348 aa)
D5G962_TUBMMUncharacterized protein. (148 aa)
D5GAV6_TUBMMDNA helicase; Belongs to the MCM family. (847 aa)
D5GCG5_TUBMMDNA helicase; Belongs to the MCM family. (772 aa)
D5GCR9_TUBMMDNA ligase. (976 aa)
D5GFI1_TUBMMDNA helicase; Belongs to the MCM family. (797 aa)
D5GFV6_TUBMMProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (285 aa)
D5GGI0_TUBMMRNase H domain-containing protein. (405 aa)
D5GGS5_TUBMMAAA domain-containing protein. (358 aa)
D5GGS6_TUBMMDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2165 aa)
D5GH17_TUBMMDNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (652 aa)
D5GH90_TUBMMDNA ligase. (852 aa)
D5GHR5_TUBMMDNA primase; Belongs to the eukaryotic-type primase small subunit family. (516 aa)
D5GHT0_TUBMMDNA polymerase. (1067 aa)
D5GIV2_TUBMMAAA domain-containing protein. (372 aa)
D5GJA0_TUBMMUncharacterized protein. (430 aa)
D5GJM1_TUBMMAAA domain-containing protein. (387 aa)
D5GJX0_TUBMMUncharacterized protein. (361 aa)
D5GK70_TUBMMRibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (336 aa)
D5GKW2_TUBMMReplication factor C subunit 1. (1025 aa)
D5GL82_TUBMMDNA helicase; Belongs to the MCM family. (888 aa)
D5GLS4_TUBMMDNA_LIGASE_A3 domain-containing protein. (334 aa)
D5GLW6_TUBMMDNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (540 aa)
D5GM03_TUBMMDNA_pol_E_B domain-containing protein. (663 aa)
Your Current Organism:
Tuber melanosporum
NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28
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