(36 nodes) Phagosome network (Tuber melanosporum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	D5G3X3_TUBMM	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (125 aa)
	D5G4M0_TUBMM	Uncharacterized protein. (70 aa)
	D5G5I8_TUBMM	t-SNARE coiled-coil homology domain-containing protein. (352 aa)
	D5G5K2_TUBMM	Uncharacterized protein. (613 aa)
	D5G5U3_TUBMM	Uncharacterized protein. (656 aa)
	D5G7H9_TUBMM	Uncharacterized protein; Belongs to the synaptobrevin family. (214 aa)
	D5G7Y1_TUBMM	Uncharacterized protein. (218 aa)
	D5G8P4_TUBMM	Uncharacterized protein. (196 aa)
	D5G8T3_TUBMM	Uncharacterized protein. (496 aa)
	D5G8U8_TUBMM	Phosphatidylinositol 3-kinase VPS34. (812 aa)
	D5G9W1_TUBMM	Uncharacterized protein. (158 aa)
	D5G9Z3_TUBMM	Tubulin_C domain-containing protein; Belongs to the tubulin family. (273 aa)
	D5GAC4_TUBMM	Plug_translocon domain-containing protein. (498 aa)
	D5GAX3_TUBMM	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (820 aa)
	D5GAY7_TUBMM	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (466 aa)
	D5GB22_TUBMM	Uncharacterized protein. (205 aa)
	D5GB73_TUBMM	FAD-binding FR-type domain-containing protein. (551 aa)
	D5GBD9_TUBMM	Uncharacterized protein. (209 aa)
	D5GBI3_TUBMM	Uncharacterized protein. (317 aa)
	D5GBJ1_TUBMM	Uncharacterized protein. (219 aa)
	D5GCV7_TUBMM	Uncharacterized protein. (4187 aa)
	D5GCZ9_TUBMM	Uncharacterized protein. (343 aa)
	D5GD30_TUBMM	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (689 aa)
	D5GFC8_TUBMM	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (387 aa)
	D5GHA4_TUBMM	Uncharacterized protein. (202 aa)
	D5GIK8_TUBMM	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	D5GJ38_TUBMM	Uncharacterized protein. (503 aa)
	D5GK15_TUBMM	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
	D5GKM0_TUBMM	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (411 aa)
	D5GL75_TUBMM	Uncharacterized protein. (252 aa)
	D5GLV7_TUBMM	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (161 aa)
	D5GM50_TUBMM	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (198 aa)
	D5GME0_TUBMM	Uncharacterized protein. (255 aa)
	D5GN00_TUBMM	ATP-synt_ab domain-containing protein. (312 aa)
	D5GNF8_TUBMM	Uncharacterized protein. (2319 aa)
	D5GQ43_TUBMM	Uncharacterized protein. (208 aa)

Your Current Organism:

Tuber melanosporum

NCBI taxonomy Id: 656061
Other names: T. melanosporum Mel28, Tuber melanosporum Mel28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
D5G3X3_TUBMM	D5G5K2_TUBMM	D5G3X3	D5G5K2	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.999
D5G3X3_TUBMM	D5GAX3_TUBMM	D5G3X3	D5GAX3	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.999
D5G3X3_TUBMM	D5GAY7_TUBMM	D5G3X3	D5GAY7	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.999
D5G3X3_TUBMM	D5GBD9_TUBMM	D5G3X3	D5GBD9	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.999
D5G3X3_TUBMM	D5GCZ9_TUBMM	D5G3X3	D5GCZ9	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.981
D5G3X3_TUBMM	D5GFC8_TUBMM	D5G3X3	D5GFC8	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
D5G3X3_TUBMM	D5GL75_TUBMM	D5G3X3	D5GL75	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.981
D5G3X3_TUBMM	D5GLV7_TUBMM	D5G3X3	D5GLV7	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
D5G3X3_TUBMM	D5GM50_TUBMM	D5G3X3	D5GM50	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	0.999
D5G3X3_TUBMM	D5GME0_TUBMM	D5G3X3	D5GME0	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.999
D5G3X3_TUBMM	D5GN00_TUBMM	D5G3X3	D5GN00	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATP-synt_ab domain-containing protein.	0.989
D5G3X3_TUBMM	D5GQ43_TUBMM	D5G3X3	D5GQ43	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.999
D5G4M0_TUBMM	D5G9W1_TUBMM	D5G4M0	D5G9W1	Uncharacterized protein.	Uncharacterized protein.	0.999
D5G4M0_TUBMM	D5GAC4_TUBMM	D5G4M0	D5GAC4	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.999
D5G5I8_TUBMM	D5G7H9_TUBMM	D5G5I8	D5G7H9	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.926
D5G5K2_TUBMM	D5G3X3_TUBMM	D5G5K2	D5G3X3	Uncharacterized protein.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
D5G5K2_TUBMM	D5GAX3_TUBMM	D5G5K2	D5GAX3	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.999
D5G5K2_TUBMM	D5GAY7_TUBMM	D5G5K2	D5GAY7	Uncharacterized protein.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.999
D5G5K2_TUBMM	D5GBD9_TUBMM	D5G5K2	D5GBD9	Uncharacterized protein.	Uncharacterized protein.	0.999
D5G5K2_TUBMM	D5GCZ9_TUBMM	D5G5K2	D5GCZ9	Uncharacterized protein.	Uncharacterized protein.	0.996