92 items (Pseudogymnoascus destructans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GMDG_05103	Uncharacterized protein. (236 aa)
	GMDG_05120	PINc domain-containing protein. (193 aa)
	GMDG_05164	Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1634 aa)
	GMDG_05194	Uncharacterized protein. (842 aa)
	GMDG_05286	Uncharacterized protein; Belongs to the helicase family. Dicer subfamily. (1377 aa)
	GMDG_00134	Uncharacterized protein. (1673 aa)
	GMDG_05244	CCHC-type domain-containing protein. (361 aa)
	GMDG_05210	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (721 aa)
	GMDG_00977	Uncharacterized protein. (275 aa)
	GMDG_05287	Piwi domain-containing protein. (973 aa)
	GMDG_05659	Uncharacterized protein. (174 aa)
	GMDG_00112	Uncharacterized protein. (375 aa)
	GMDG_05314	Uncharacterized protein. (100 aa)
	GMDG_05388	Uncharacterized protein. (725 aa)
	GMDG_06265	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (473 aa)
	GMDG_01207	Endo/exonuclease/phosphatase domain-containing protein. (657 aa)
	GMDG_05459	CCHC-type domain-containing protein. (300 aa)
	GMDG_06214	Protein kinase domain-containing protein. (322 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
	GMDG_05695	ERCC4 domain-containing protein. (682 aa)
	GMDG_06622	CCHC-type domain-containing protein. (406 aa)
	GMDG_06477	IRE protein kinase. (1188 aa)
	GMDG_05935	Uncharacterized protein. (1232 aa)
	GMDG_05992	TNase-like domain-containing protein. (279 aa)
	GMDG_01433	Uncharacterized protein; Belongs to the argonaute family. (926 aa)
	GMDG_06828	ERCC4 domain-containing protein. (936 aa)
	GMDG_01292	CCHC-type domain-containing protein. (437 aa)
	GMDG_01307	Uncharacterized protein. (253 aa)
	GMDG_06784	Uncharacterized protein. (239 aa)
	GMDG_01365	Uncharacterized protein. (775 aa)
	GMDG_07119	SAE2 domain-containing protein. (817 aa)
	GMDG_07422	CCHC-type domain-containing protein. (300 aa)
	GMDG_07452	Uncharacterized protein. (447 aa)
	GMDG_07234	CCHC-type domain-containing protein. (390 aa)
	GMDG_07538	CCHC-type domain-containing protein. (380 aa)
	GMDG_01863	tRNA_int_end_N2 domain-containing protein. (468 aa)
	GMDG_07500	CCHC-type domain-containing protein. (287 aa)
	SLX1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (329 aa)
	GMDG_07648	Uncharacterized protein. (641 aa)
	GMDG_07708	Uncharacterized protein. (174 aa)
	GMDG_07713	Uncharacterized protein. (154 aa)
	GMDG_01804	Uncharacterized protein. (378 aa)
	GMDG_01834	Smr domain-containing protein. (550 aa)
	GMDG_01794	Uncharacterized protein. (307 aa)
	GMDG_07718	RNase H domain-containing protein. (162 aa)
	GMDG_07840	Uncharacterized protein; Belongs to the argonaute family. (989 aa)
	GMDG_01866	DBR1 domain-containing protein. (568 aa)
	GMDG_07651	Uncharacterized protein. (305 aa)
	GMDG_08034	CCHC-type domain-containing protein. (427 aa)
	GMDG_07549	tRNA_int_endo domain-containing protein. (647 aa)
	GMDG_08051	Uncharacterized protein. (362 aa)
	GMDG_08149	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (849 aa)
	GMDG_02311	Uncharacterized protein. (302 aa)
	GMDG_08164	RNase III domain-containing protein. (257 aa)
	GMDG_08532	CCHC-type domain-containing protein. (393 aa)
	GMDG_08339	Uncharacterized protein. (67 aa)
	GMDG_02762	Uncharacterized protein. (364 aa)
	GMDG_00313	Uncharacterized protein. (972 aa)
	GMDG_08468	Uncharacterized protein. (245 aa)
	GMDG_02266	Endonuclease. (341 aa)
	SLX4	Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (833 aa)
	GMDG_08224	Uncharacterized protein. (364 aa)
	GMDG_02856	Uncharacterized protein. (451 aa)
	GMDG_02886	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (397 aa)
	GMDG_08621	Uncharacterized protein. (95 aa)
	GMDG_03384	ERCC4 domain-containing protein. (329 aa)
	GMDG_00533	Uncharacterized protein. (176 aa)
	GMDG_08668	CCHC-type domain-containing protein. (355 aa)
	GMDG_00427	Uncharacterized protein. (355 aa)
	GMDG_00442	Uncharacterized protein. (87 aa)
	GMDG_03475	RNase III domain-containing protein. (410 aa)
	GMDG_03628	SAP domain-containing protein. (336 aa)
	GMDG_03738	tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (308 aa)
	GMDG_03508	CCHC-type domain-containing protein. (393 aa)
	GMDG_02874	Uncharacterized protein. (831 aa)
	GMDG_03906	Uncharacterized protein. (92 aa)
	GMDG_03575	Uncharacterized protein. (219 aa)
	GMDG_08682	Uncharacterized protein. (351 aa)
	GMDG_03905	Uncharacterized protein. (247 aa)
	GMDG_04091	Uncharacterized protein. (190 aa)
	GMDG_03282	RNase III domain-containing protein. (399 aa)
	GMDG_08706	CCHC-type domain-containing protein. (323 aa)
	GMDG_04500	CCHC-type domain-containing protein. (410 aa)
	GMDG_04437	Uncharacterized protein. (661 aa)
	GMDG_04092	Uncharacterized protein. (429 aa)
	GMDG_04742	18S rRNA biogenesis protein RCL1. (434 aa)
	GMDG_03780	Uncharacterized protein. (366 aa)
	GMDG_04838	Uncharacterized protein. (905 aa)
	GMDG_00797	Uncharacterized protein; Belongs to the RNase T2 family. (366 aa)
	GMDG_04904	CCHC-type domain-containing protein. (379 aa)
	GMDG_04270	Exosome complex exonuclease DIS3/RRP44; Belongs to the RNR ribonuclease family. (994 aa)
	GMDG_04336	Uncharacterized protein. (137 aa)

Your Current Organism:

Pseudogymnoascus destructans

NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEN1	GMDG_00112	L8FSI2	L8FPW2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.534
FEN1	GMDG_00134	L8FSI2	L8FMQ8	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.974
FEN1	GMDG_00533	L8FSI2	L8G6J5	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.467
FEN1	GMDG_01207	L8FSI2	L8FRN9	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Endo/exonuclease/phosphatase domain-containing protein.	0.993
FEN1	GMDG_01365	L8FSI2	L8FVQ2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.885
FEN1	GMDG_02266	L8FSI2	L8G4I4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Endonuclease.	0.649
FEN1	GMDG_02886	L8FSI2	L8G5U5	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.	0.735
FEN1	GMDG_03384	L8FSI2	L8G6H7	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	ERCC4 domain-containing protein.	0.897
FEN1	GMDG_03628	L8FSI2	L8G7G1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	SAP domain-containing protein.	0.422
FEN1	GMDG_03905	L8FSI2	L8G8Y8	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.754
FEN1	GMDG_03906	L8FSI2	L8G7X4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.754
FEN1	GMDG_04336	L8FSI2	L8GCQ6	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.467
FEN1	GMDG_05194	L8FSI2	L8FM79	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.506
FEN1	GMDG_05210	L8FSI2	L8FNL1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.980
FEN1	GMDG_05695	L8FSI2	L8FSR3	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	ERCC4 domain-containing protein.	0.567
FEN1	GMDG_05935	L8FSI2	L8FTT5	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.512
FEN1	GMDG_06828	L8FSI2	L8FUG9	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	ERCC4 domain-containing protein.	0.862
FEN1	GMDG_07119	L8FSI2	L8FW33	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	SAE2 domain-containing protein.	0.797
FEN1	GMDG_07718	L8FSI2	L8FYS0	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	RNase H domain-containing protein.	0.473
FEN1	SLX1	L8FSI2	L8FXV8	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.714