STRINGSTRING
MCM7 MCM7 GMDG_08535 GMDG_08535 GMDG_08531 GMDG_08531 GMDG_02382 GMDG_02382 GMDG_02480 GMDG_02480 GMDG_06129 GMDG_06129 GMDG_08735 GMDG_08735 GMDG_03946 GMDG_03946 GMDG_03758 GMDG_03758
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (810 aa)
GMDG_08535Uncharacterized protein. (286 aa)
GMDG_08531Uncharacterized protein. (389 aa)
GMDG_02382Uncharacterized protein. (1504 aa)
GMDG_02480Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
GMDG_06129DNA helicase; Belongs to the MCM family. (1027 aa)
GMDG_08735Uncharacterized protein. (297 aa)
GMDG_03946DNA helicase; Belongs to the MCM family. (854 aa)
GMDG_03758DNA helicase; Belongs to the MCM family. (947 aa)
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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