103 items (Pseudogymnoascus destructans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GMDG_08061	DNA polymerase. (1445 aa)
	GMDG_07664	Uncharacterized protein. (475 aa)
	GMDG_08051	Uncharacterized protein. (362 aa)
	GMDG_02305	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (388 aa)
	GMDG_07930	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1728 aa)
	GMDG_07879	Uncharacterized protein. (242 aa)
	GMDG_02018	Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (383 aa)
	GMDG_08034	CCHC-type domain-containing protein. (427 aa)
	GMDG_07193	DNA-directed RNA polymerase II subunit C. (342 aa)
	GMDG_07183	Uncharacterized protein. (194 aa)
	GMDG_01895	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1708 aa)
	GMDG_07788	Ethanolamine-phosphate cytidylyltransferase. (446 aa)
	MET3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
	GMDG_00170	Uncharacterized protein. (641 aa)
	GMDG_07489	Uncharacterized protein. (516 aa)
	GMDG_01907	Uncharacterized protein. (431 aa)
	GMDG_07500	CCHC-type domain-containing protein. (287 aa)
	GMDG_07281	Uncharacterized protein. (1085 aa)
	GMDG_07332	Mannose-1-phosphate guanylyltransferase. (468 aa)
	GMDG_07538	CCHC-type domain-containing protein. (380 aa)
	GMDG_07523	DNA polymerase. (1102 aa)
	GMDG_07234	CCHC-type domain-containing protein. (390 aa)
	GMDG_07452	Uncharacterized protein. (447 aa)
	GMDG_07422	CCHC-type domain-containing protein. (300 aa)
	GMDG_01594	RPOLD domain-containing protein. (375 aa)
	GMDG_07159	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1224 aa)
	GMDG_07206	UmuC domain-containing protein. (616 aa)
	NCS6	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (438 aa)
	GMDG_01571	UTP--glucose-1-phosphate uridylyltransferase. (527 aa)
	GMDG_01480	Uncharacterized protein. (236 aa)
	GMDG_06729	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (598 aa)
	GMDG_04700	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1193 aa)
	GMDG_01292	CCHC-type domain-containing protein. (437 aa)
	GMDG_08977	Uncharacterized protein. (86 aa)
	GMDG_06549	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1478 aa)
	GMDG_06437	Uncharacterized protein. (547 aa)
	GMDG_06622	CCHC-type domain-containing protein. (406 aa)
	GMDG_06341	RNA-dependent RNA polymerase. (1330 aa)
	GMDG_05982	APH domain-containing protein. (570 aa)
	GMDG_05459	CCHC-type domain-containing protein. (300 aa)
	GMDG_01212	DNA polymerase. (1742 aa)
	NCS2	Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (382 aa)
	GMDG_01296	UmuC domain-containing protein. (625 aa)
	GMDG_05314	Uncharacterized protein. (100 aa)
	GMDG_05309	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (546 aa)
	GMDG_06131	YrdC-like domain-containing protein. (534 aa)
	GMDG_01230	Fido domain-containing protein. (306 aa)
	GMDG_01175	Uncharacterized protein. (1568 aa)
	GMDG_05707	Uncharacterized protein. (207 aa)
	GMDG_05919	CTP_transf_like domain-containing protein. (375 aa)
	GMDG_00002	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1187 aa)
	uba4	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (481 aa)
	GMDG_05244	CCHC-type domain-containing protein. (361 aa)
	GMDG_05091	APH domain-containing protein. (511 aa)
	GMDG_05085	Uncharacterized protein. (158 aa)
	GMDG_05359	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (333 aa)
	GMDG_00933	Uncharacterized protein. (1241 aa)
	GMDG_05270	HORMA domain-containing protein. (284 aa)
	GMDG_05113	RNA_pol_L_2 domain-containing protein. (189 aa)
	GMDG_05103	Uncharacterized protein. (236 aa)
	GMDG_08682	Uncharacterized protein. (351 aa)
	GMDG_00530	Uncharacterized protein. (77 aa)
	GMDG_08706	CCHC-type domain-containing protein. (323 aa)
	GMDG_03876	Uncharacterized protein. (325 aa)
	GMDG_04088	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (679 aa)
	GMDG_03987	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1272 aa)
	GMDG_03502	Uncharacterized protein. (643 aa)
	GMDG_04500	CCHC-type domain-containing protein. (410 aa)
	GMDG_04437	Uncharacterized protein. (661 aa)
	GMDG_04357	Uncharacterized protein. (413 aa)
	GMDG_04478	ATP_transf domain-containing protein. (166 aa)
	GMDG_03749	Uncharacterized protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (583 aa)
	GMDG_03780	Uncharacterized protein. (366 aa)
	GMDG_04904	CCHC-type domain-containing protein. (379 aa)
	GMDG_03757	Uncharacterized protein. (460 aa)
	GMDG_03981	Uncharacterized protein. (319 aa)
	GMDG_03600	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (678 aa)
	GMDG_03508	CCHC-type domain-containing protein. (393 aa)
	GMDG_03748	Uncharacterized protein. (536 aa)
	GMDG_08668	CCHC-type domain-containing protein. (355 aa)
	GMDG_08461	APH domain-containing protein. (511 aa)
	GMDG_08621	Uncharacterized protein. (95 aa)
	GMDG_03397	Mannose-1-phosphate guanyltransferase. (364 aa)
	GMDG_02556	tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (289 aa)
	GMDG_08401	Uncharacterized protein. (753 aa)
	GMDG_02856	Uncharacterized protein. (451 aa)
	GMDG_08229	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (247 aa)
	GMDG_08224	Uncharacterized protein. (364 aa)
	GMDG_02318	Phosphatidate cytidylyltransferase; Belongs to the CDS family. (451 aa)
	GMDG_03071	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2224 aa)
	GMDG_03061	W2 domain-containing protein. (727 aa)
	GMDG_02904	Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family. (297 aa)
	GMDG_08468	Uncharacterized protein. (245 aa)
	GMDG_00395	BRCT domain-containing protein. (784 aa)
	GMDG_02762	Uncharacterized protein. (364 aa)
	GMDG_08339	Uncharacterized protein. (67 aa)
	GMDG_08532	CCHC-type domain-containing protein. (393 aa)
	GMDG_02446	DNA polymerase gamma 1. (1135 aa)
	GMDG_08436	BPL/LPL catalytic domain-containing protein. (408 aa)
	GMDG_02315	DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1438 aa)
	GMDG_07821	DNA-directed RNA Polymerase II subunit L. (76 aa)
	GMDG_00350	Uncharacterized protein. (163 aa)
	GMDG_08331	Uncharacterized protein. (269 aa)

Your Current Organism:

Pseudogymnoascus destructans

NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GMDG_00002	GMDG_00350	L8FPN3	L8G219	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999
GMDG_00002	GMDG_00530	L8FPN3	L8G8V2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999
GMDG_00002	GMDG_01480	L8FPN3	L8FV35	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999
GMDG_00002	GMDG_01594	L8FPN3	L8FX09	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOLD domain-containing protein.	0.999
GMDG_00002	GMDG_01895	L8FPN3	L8FZB1	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.991
GMDG_00002	GMDG_02305	L8FPN3	L8G0X9	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family.	0.692
GMDG_00002	GMDG_02315	L8FPN3	L8G2U5	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.	0.642
GMDG_00002	GMDG_03876	L8FPN3	L8G9I3	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.997
GMDG_00002	GMDG_03981	L8FPN3	L8G8K0	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.972
GMDG_00002	GMDG_04700	L8FPN3	L8GCB6	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.874
GMDG_00002	GMDG_05113	L8FPN3	L8FLZ9	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA_pol_L_2 domain-containing protein.	0.959
GMDG_00002	GMDG_05359	L8FPN3	L8FMV7	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.	0.997
GMDG_00002	GMDG_05707	L8FPN3	L8FQL5	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.997
GMDG_00002	GMDG_06549	L8FPN3	L8FU88	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
GMDG_00002	GMDG_07193	L8FPN3	L8FZL7	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase II subunit C.	0.976
GMDG_00002	GMDG_07821	L8FPN3	L8G2I2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA Polymerase II subunit L.	0.999
GMDG_00002	GMDG_07930	L8FPN3	L8G0N1	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.808
GMDG_00002	GMDG_08229	L8FPN3	L8G515	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.	0.991
GMDG_00002	GMDG_08977	L8FPN3	L8FU92	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.940
GMDG_00170	GMDG_00395	L8FYW8	L8G3Q9	Uncharacterized protein.	BRCT domain-containing protein.	0.410