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GMDG_01084 GMDG_01084 GMDG_03286 GMDG_03286 GMDG_01924 GMDG_01924 MCM7 MCM7 GMDG_03946 GMDG_03946 GMDG_03758 GMDG_03758 GMDG_00113 GMDG_00113 GMDG_05766 GMDG_05766 GMDG_06129 GMDG_06129
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GMDG_01084DNA helicase; Belongs to the MCM family. (720 aa)
GMDG_03286DNA helicase; Belongs to the MCM family. (868 aa)
GMDG_01924FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (552 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (810 aa)
GMDG_03946DNA helicase; Belongs to the MCM family. (854 aa)
GMDG_03758DNA helicase; Belongs to the MCM family. (947 aa)
GMDG_00113Zf-primase domain-containing protein. (793 aa)
GMDG_05766MRC1 domain-containing protein. (1376 aa)
GMDG_06129DNA helicase; Belongs to the MCM family. (1027 aa)
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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