STRINGSTRING
GMDG_03286 GMDG_03286 GMDG_04897 GMDG_04897 GMDG_00685 GMDG_00685 MCM7 MCM7 GMDG_00617 GMDG_00617 GMDG_03031 GMDG_03031 GMDG_03260 GMDG_03260 GMDG_02440 GMDG_02440 GMDG_07709 GMDG_07709 GMDG_01171 GMDG_01171 GMDG_01084 GMDG_01084
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GMDG_03286DNA helicase; Belongs to the MCM family. (868 aa)
GMDG_04897Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (489 aa)
GMDG_00685Uncharacterized protein. (1699 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (810 aa)
GMDG_00617Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (502 aa)
GMDG_03031Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (427 aa)
GMDG_03260Stc1 domain-containing protein. (364 aa)
GMDG_02440CULLIN_2 domain-containing protein; Belongs to the cullin family. (854 aa)
GMDG_07709ATP-dependent RNA helicase sub2. (439 aa)
GMDG_01171PHD domain-containing protein. (1026 aa)
GMDG_01084DNA helicase; Belongs to the MCM family. (720 aa)
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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