27 items (Pseudogymnoascus destructans) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	GMDG_00113	Zf-primase domain-containing protein. (793 aa)
	GMDG_05629	Uncharacterized protein. (236 aa)
	GMDG_05567	Uncharacterized protein. (100 aa)
	GMDG_05766	MRC1 domain-containing protein. (1376 aa)
	GMDG_01084	DNA helicase; Belongs to the MCM family. (720 aa)
	GMDG_05309	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (546 aa)
	GMDG_06129	DNA helicase; Belongs to the MCM family. (1027 aa)
	GMDG_01453	Uncharacterized protein. (856 aa)
	GMDG_07057	DNA helicase. (674 aa)
	GMDG_07523	DNA polymerase. (1102 aa)
	GMDG_01907	Uncharacterized protein. (431 aa)
	GMDG_01879	Uncharacterized protein. (237 aa)
	GMDG_07489	Uncharacterized protein. (516 aa)
	GMDG_01924	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (552 aa)
	GMDG_00170	Uncharacterized protein. (641 aa)
	GMDG_01806	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (669 aa)
	GMDG_08061	DNA polymerase. (1445 aa)
	GMDG_02480	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	GMDG_08174	WD_REPEATS_REGION domain-containing protein. (756 aa)
	GMDG_03022	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (912 aa)
	GMDG_03286	DNA helicase; Belongs to the MCM family. (868 aa)
	GMDG_03758	DNA helicase; Belongs to the MCM family. (947 aa)
	GMDG_03464	WD_REPEATS_REGION domain-containing protein. (842 aa)
	GMDG_03946	DNA helicase; Belongs to the MCM family. (854 aa)
	GMDG_03757	Uncharacterized protein. (460 aa)
	GMDG_03881	Uncharacterized protein. (286 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (810 aa)

Your Current Organism:

Pseudogymnoascus destructans

NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GMDG_00113	GMDG_00170	L8FLC6	L8FYW8	Zf-primase domain-containing protein.	Uncharacterized protein.	0.645
GMDG_00113	GMDG_01084	L8FLC6	L8FPW0	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.991
GMDG_00113	GMDG_01453	L8FLC6	L8FUE7	Zf-primase domain-containing protein.	Uncharacterized protein.	0.996
GMDG_00113	GMDG_01806	L8FLC6	L8G119	Zf-primase domain-containing protein.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.857
GMDG_00113	GMDG_01907	L8FLC6	L8FY53	Zf-primase domain-containing protein.	Uncharacterized protein.	0.911
GMDG_00113	GMDG_02480	L8FLC6	L8G203	Zf-primase domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.766
GMDG_00113	GMDG_03022	L8FLC6	L8G521	Zf-primase domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.702
GMDG_00113	GMDG_03286	L8FLC6	L8G5U0	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.990
GMDG_00113	GMDG_03464	L8FLC6	L8G818	Zf-primase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.851
GMDG_00113	GMDG_03758	L8FLC6	L8G7I8	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.996
GMDG_00113	GMDG_03881	L8FLC6	L8G9I7	Zf-primase domain-containing protein.	Uncharacterized protein.	0.724
GMDG_00113	GMDG_03946	L8FLC6	L8G8G1	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.993
GMDG_00113	GMDG_05309	L8FLC6	L8FRB4	Zf-primase domain-containing protein.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.900
GMDG_00113	GMDG_05766	L8FLC6	L8FPB7	Zf-primase domain-containing protein.	MRC1 domain-containing protein.	0.677
GMDG_00113	GMDG_06129	L8FLC6	L8FSD2	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.996
GMDG_00113	GMDG_07523	L8FLC6	L8FXI4	Zf-primase domain-containing protein.	DNA polymerase.	0.866
GMDG_00113	GMDG_08061	L8FLC6	L8G1P2	Zf-primase domain-containing protein.	DNA polymerase.	0.913
GMDG_00113	GMDG_08174	L8FLC6	L8G2H0	Zf-primase domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.411
GMDG_00113	MCM7	L8FLC6	L8G9V8	Zf-primase domain-containing protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.996
GMDG_00170	GMDG_00113	L8FYW8	L8FLC6	Uncharacterized protein.	Zf-primase domain-containing protein.	0.645