STRINGSTRING
GMDG_08885 GMDG_08885 COQ5 COQ5 GMDG_01876 GMDG_01876 GMDG_07636 GMDG_07636 GMDG_02084 GMDG_02084 GMDG_08201 GMDG_08201 COQ3 COQ3 GMDG_02889 GMDG_02889 GMDG_08200 GMDG_08200 GMDG_02666 GMDG_02666 COQ7 COQ7 GMDG_02973 GMDG_02973 GMDG_03915 GMDG_03915 GMDG_05881 GMDG_05881 GMDG_08799 GMDG_08799 GMDG_00008 GMDG_00008 COQ6 COQ6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GMDG_08885Methyltransf_11 domain-containing protein. (183 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (318 aa)
GMDG_01876Uncharacterized protein. (382 aa)
GMDG_07636Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (457 aa)
GMDG_02084Uncharacterized protein. (75 aa)
GMDG_08201Uncharacterized protein. (97 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (279 aa)
GMDG_02889Uncharacterized protein. (173 aa)
GMDG_08200Methyltransf_25 domain-containing protein. (161 aa)
GMDG_026664-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (411 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (263 aa)
GMDG_02973Uncharacterized protein. (214 aa)
GMDG_03915Uncharacterized protein. (495 aa)
GMDG_05881Methyltransf_25 domain-containing protein. (169 aa)
GMDG_08799Uncharacterized protein. (218 aa)
GMDG_00008Uncharacterized protein. (342 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (489 aa)
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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