128 items (Pseudogymnoascus destructans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GMDG_06643	Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (727 aa)
	GMDG_05905	Uncharacterized protein. (122 aa)
	GMDG_05930	Uncharacterized protein; Belongs to the actin family. (754 aa)
	GMDG_07422	CCHC-type domain-containing protein. (300 aa)
	GMDG_06594	CMGC/CDK/CDK7 protein kinase. (301 aa)
	GMDG_07110	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (128 aa)
	GMDG_07075	CDK-activating kinase assembly factor MAT1. (351 aa)
	GMDG_01480	Uncharacterized protein. (236 aa)
	GMDG_01292	CCHC-type domain-containing protein. (437 aa)
	GMDG_01462	Uncharacterized protein. (286 aa)
	GMDG_06828	ERCC4 domain-containing protein. (936 aa)
	GMDG_05935	Uncharacterized protein. (1232 aa)
	GMDG_07452	Uncharacterized protein. (447 aa)
	GMDG_07234	CCHC-type domain-containing protein. (390 aa)
	GMDG_07538	CCHC-type domain-containing protein. (380 aa)
	GMDG_07500	CCHC-type domain-containing protein. (287 aa)
	GMDG_07653	Transcription elongation factor S-II. (301 aa)
	GMDG_07570	RRM domain-containing protein. (152 aa)
	GMDG_01879	Uncharacterized protein. (237 aa)
	GMDG_01774	Uncharacterized protein. (108 aa)
	GMDG_07576	Replication factor C subunit 1. (1046 aa)
	GMDG_00238	Pre-mRNA-splicing factor ISY1. (243 aa)
	GMDG_07626	Uncharacterized protein. (456 aa)
	GMDG_07193	DNA-directed RNA polymerase II subunit C. (342 aa)
	GMDG_08034	CCHC-type domain-containing protein. (427 aa)
	GMDG_07764	PCI domain-containing protein. (466 aa)
	GMDG_00274	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (470 aa)
	GMDG_07930	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1728 aa)
	GMDG_01893	DNA repair helicase rad15. (795 aa)
	GMDG_02480	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	GMDG_00350	Uncharacterized protein. (163 aa)
	GMDG_02005	Zds_C domain-containing protein. (919 aa)
	GMDG_07821	DNA-directed RNA Polymerase II subunit L. (76 aa)
	GMDG_08446	CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (384 aa)
	GMDG_02083	BZIP domain-containing protein. (212 aa)
	GMDG_08532	CCHC-type domain-containing protein. (393 aa)
	GMDG_02440	CULLIN_2 domain-containing protein; Belongs to the cullin family. (854 aa)
	GMDG_08339	Uncharacterized protein. (67 aa)
	GMDG_02762	Uncharacterized protein. (364 aa)
	GMDG_02759	Uncharacterized protein. (184 aa)
	GMDG_02626	PAPA-1 domain-containing protein. (381 aa)
	GMDG_03083	CCHC-type domain-containing protein. (210 aa)
	GMDG_02370	Uncharacterized protein. (216 aa)
	GMDG_02760	Uncharacterized protein. (301 aa)
	GMDG_02423	Uncharacterized protein. (841 aa)
	GMDG_02481	Uncharacterized protein. (500 aa)
	GMDG_02856	Uncharacterized protein. (451 aa)
	GMDG_08621	Uncharacterized protein. (95 aa)
	GMDG_03363	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (457 aa)
	GMDG_08665	Chromo domain-containing protein. (198 aa)
	GMDG_03399	Uncharacterized protein. (637 aa)
	GMDG_03511	DNA excision repair protein ERCC-3. (869 aa)
	GMDG_08668	CCHC-type domain-containing protein. (355 aa)
	GMDG_03360	Replication factor C subunit 5. (352 aa)
	GMDG_03391	Polyubiquitin. (381 aa)
	GMDG_03508	CCHC-type domain-containing protein. (393 aa)
	GMDG_03735	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (151 aa)
	GMDG_00582	Poly [ADP-ribose] polymerase. (703 aa)
	GMDG_05113	RNA_pol_L_2 domain-containing protein. (189 aa)
	GMDG_05194	Uncharacterized protein. (842 aa)
	GMDG_00955	Replication factor C subunit 2/4. (357 aa)
	GMDG_00970	RING-box protein 1. (127 aa)
	GMDG_03916	BZIP domain-containing protein. (409 aa)
	GMDG_03479	Replication factor C subunit 3/5. (393 aa)
	GMDG_03038	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (529 aa)
	GMDG_08675	Chromo domain-containing protein. (210 aa)
	GMDG_03719	Amino_oxidase domain-containing protein. (581 aa)
	GMDG_03729	DNA-directed RNA polymerase II subunit D. (149 aa)
	GMDG_03757	Uncharacterized protein. (460 aa)
	GMDG_08637	Uncharacterized protein. (580 aa)
	GMDG_08682	Uncharacterized protein. (351 aa)
	GMDG_00530	Uncharacterized protein. (77 aa)
	GMDG_03905	Uncharacterized protein. (247 aa)
	GMDG_04206	Uncharacterized protein. (473 aa)
	GMDG_08706	CCHC-type domain-containing protein. (323 aa)
	GMDG_08652	Uncharacterized protein. (121 aa)
	GMDG_03881	Uncharacterized protein. (286 aa)
	GMDG_03987	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1272 aa)
	GMDG_08710	Uncharacterized protein. (91 aa)
	GMDG_03536	Uncharacterized protein; Belongs to the peptidase C19 family. (1187 aa)
	GMDG_04440	Uncharacterized protein. (564 aa)
	GMDG_00685	Uncharacterized protein. (1699 aa)
	GMDG_00690	CYCLIN domain-containing protein; Belongs to the cyclin family. (380 aa)
	GMDG_04500	CCHC-type domain-containing protein. (410 aa)
	GMDG_04437	Uncharacterized protein. (661 aa)
	GMDG_08717	Uncharacterized protein. (210 aa)
	GMDG_04087	CBFD_NFYB_HMF domain-containing protein. (199 aa)
	GMDG_04184	MPN domain-containing protein. (423 aa)
	GMDG_04679	Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome. (1433 aa)
	GMDG_04737	AAA domain-containing protein. (389 aa)
	GMDG_03744	Pre-mRNA-splicing factor syf-1. (822 aa)
	GMDG_04658	USP domain-containing protein; Belongs to the peptidase C19 family. (1331 aa)
	GMDG_04676	Uncharacterized protein. (1241 aa)
	GMDG_04371	Chromo domain-containing protein. (118 aa)
	GMDG_03874	CPSF_A domain-containing protein. (1138 aa)
	GMDG_04602	BRCT domain-containing protein. (287 aa)
	GMDG_04904	CCHC-type domain-containing protein. (379 aa)
	GMDG_04883	Uncharacterized protein. (472 aa)
	GMDG_04550	XPA_C domain-containing protein. (376 aa)
	GMDG_04979	PPIase cyclophilin-type domain-containing protein. (367 aa)
	GMDG_04999	Uncharacterized protein. (1144 aa)
	GMDG_03906	Uncharacterized protein. (92 aa)
	GMDG_05031	Uncharacterized protein. (408 aa)
	GMDG_05369	PCI domain-containing protein. (275 aa)
	GMDG_05075	Uncharacterized protein. (237 aa)
	GMDG_05475	Uncharacterized protein. (434 aa)
	GMDG_05244	CCHC-type domain-containing protein. (361 aa)
	GMDG_05195	DNA-directed RNA polymerase II subunit G. (171 aa)
	GMDG_05381	COP9 signalosome complex subunit 5. (345 aa)
	GMDG_05651	PCI domain-containing protein. (497 aa)
	GMDG_08809	Uncharacterized protein. (115 aa)
	GMDG_05778	Uncharacterized protein. (71 aa)
	GMDG_05725	CCHC-type domain-containing protein. (124 aa)
	GMDG_00042	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (491 aa)
	GMDG_05958	AAA domain-containing protein. (1243 aa)
	GMDG_05775	Uncharacterized protein. (135 aa)
	GMDG_06067	Uncharacterized protein. (228 aa)
	GMDG_05208	Uncharacterized protein. (658 aa)
	GMDG_06064	Uncharacterized protein. (363 aa)
	GMDG_08909	Chromo domain-containing protein. (110 aa)
	GMDG_05314	Uncharacterized protein. (100 aa)
	GMDG_01296	UmuC domain-containing protein. (625 aa)
	GMDG_05928	YL1_C domain-containing protein. (205 aa)
	GMDG_05459	CCHC-type domain-containing protein. (300 aa)
	GMDG_05474	PCI domain-containing protein. (399 aa)
	GMDG_06325	UV excision repair protein Rad23. (397 aa)
	GMDG_01346	Ubiquitin-40S ribosomal protein S27a. (156 aa)
	GMDG_06622	CCHC-type domain-containing protein. (406 aa)

Your Current Organism:

Pseudogymnoascus destructans

NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GMDG_00042	GMDG_00274	L8FPR1	L8G0M1	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.999
GMDG_00042	GMDG_00350	L8FPR1	L8G219	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.970
GMDG_00042	GMDG_00530	L8FPR1	L8G8V2	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.973
GMDG_00042	GMDG_00685	L8FPR1	L8GA23	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.482
GMDG_00042	GMDG_00690	L8FPR1	L8GA30	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.983
GMDG_00042	GMDG_00955	L8FPR1	L8FMN4	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Replication factor C subunit 2/4.	0.628
GMDG_00042	GMDG_01346	L8FPR1	L8FSG6	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Ubiquitin-40S ribosomal protein S27a.	0.629
GMDG_00042	GMDG_01480	L8FPR1	L8FV35	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.973
GMDG_00042	GMDG_01893	L8FPR1	L8G1H6	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA repair helicase rad15.	0.999
GMDG_00042	GMDG_02083	L8FPR1	L8G2Z5	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	BZIP domain-containing protein.	0.629
GMDG_00042	GMDG_02370	L8FPR1	L8G594	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.665
GMDG_00042	GMDG_03038	L8FPR1	L8G899	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	0.639
GMDG_00042	GMDG_03360	L8FPR1	L8G761	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Replication factor C subunit 5.	0.650
GMDG_00042	GMDG_03391	L8FPR1	L8G786	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Polyubiquitin.	0.687
GMDG_00042	GMDG_03399	L8FPR1	L8G6J1	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Uncharacterized protein.	0.999
GMDG_00042	GMDG_03479	L8FPR1	L8G832	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Replication factor C subunit 3/5.	0.625
GMDG_00042	GMDG_03511	L8FPR1	L8G6U4	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA excision repair protein ERCC-3.	0.999
GMDG_00042	GMDG_03729	L8FPR1	L8G8H8	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA-directed RNA polymerase II subunit D.	0.975
GMDG_00042	GMDG_03735	L8FPR1	L8G7V1	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.973
GMDG_00042	GMDG_03874	L8FPR1	L8GB92	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	CPSF_A domain-containing protein.	0.717